| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ERV3-1 | ERVFRD-1 | ENSP00000391594 | ENSP00000420174 | Endogenous retrovirus group 3 member 1 Env polyprotein; Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its fusogenic properties. It can inhibit cell growth through decrease expression of cyclin B1 and increased expression of p21 in vitro. TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediate [...] | Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process. | 0.514 |
| ERV3-1 | ERVW-1 | ENSP00000391594 | ENSP00000419945 | Endogenous retrovirus group 3 member 1 Env polyprotein; Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its fusogenic properties. It can inhibit cell growth through decrease expression of cyclin B1 and increased expression of p21 in vitro. TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediate [...] | Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5. | 0.468 |
| ERVFRD-1 | ERV3-1 | ENSP00000420174 | ENSP00000391594 | Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process. | Endogenous retrovirus group 3 member 1 Env polyprotein; Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its fusogenic properties. It can inhibit cell growth through decrease expression of cyclin B1 and increased expression of p21 in vitro. TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediate [...] | 0.514 |
| ERVFRD-1 | ERVW-1 | ENSP00000420174 | ENSP00000419945 | Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process. | Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5. | 0.610 |
| ERVMER34-1 | ERVV-1 | ENSP00000460602 | ENSP00000473153 | Endogenous retroviral envelope protein HEMO, secreted form; Endogenous envelope proteins originate from retroviral envelope proteins, which mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. | Endogenous retrovirus group V member 1, envelope; Belongs to the gamma type-C retroviral envelope protein family. | 0.639 |
| ERVMER34-1 | ERVV-2 | ENSP00000460602 | ENSP00000472919 | Endogenous retroviral envelope protein HEMO, secreted form; Endogenous envelope proteins originate from retroviral envelope proteins, which mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. | Endogenous retrovirus group V member 2, envelope; Belongs to the gamma type-C retroviral envelope protein family. | 0.622 |
| ERVV-1 | ERVMER34-1 | ENSP00000473153 | ENSP00000460602 | Endogenous retrovirus group V member 1, envelope; Belongs to the gamma type-C retroviral envelope protein family. | Endogenous retroviral envelope protein HEMO, secreted form; Endogenous envelope proteins originate from retroviral envelope proteins, which mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. | 0.639 |
| ERVV-1 | ERVW-1 | ENSP00000473153 | ENSP00000419945 | Endogenous retrovirus group V member 1, envelope; Belongs to the gamma type-C retroviral envelope protein family. | Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5. | 0.403 |
| ERVV-2 | ERVMER34-1 | ENSP00000472919 | ENSP00000460602 | Endogenous retrovirus group V member 2, envelope; Belongs to the gamma type-C retroviral envelope protein family. | Endogenous retroviral envelope protein HEMO, secreted form; Endogenous envelope proteins originate from retroviral envelope proteins, which mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. | 0.622 |
| ERVW-1 | ERV3-1 | ENSP00000419945 | ENSP00000391594 | Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5. | Endogenous retrovirus group 3 member 1 Env polyprotein; Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its fusogenic properties. It can inhibit cell growth through decrease expression of cyclin B1 and increased expression of p21 in vitro. TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediate [...] | 0.468 |
| ERVW-1 | ERVFRD-1 | ENSP00000419945 | ENSP00000420174 | Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5. | Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process. | 0.610 |
| ERVW-1 | ERVV-1 | ENSP00000419945 | ENSP00000473153 | Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5. | Endogenous retrovirus group V member 1, envelope; Belongs to the gamma type-C retroviral envelope protein family. | 0.403 |