STRINGSTRING
SLC39A7 SLC39A7 SLC39A4 SLC39A4 SLC39A9 SLC39A9 SLC39A13 SLC39A13 SLC39A1 SLC39A1 SLC39A2 SLC39A2 SLC39A12 SLC39A12 SLC39A14 SLC39A14 SLC39A8 SLC39A8 SLC39A10 SLC39A10 SLC39A11 SLC39A11 K7EQS6_HUMAN K7EQS6_HUMAN SLC39A5 SLC39A5 SLC39A6 SLC39A6 SLC39A3 SLC39A3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC39A7Zinc transporter SLC39A7; Zinc transporter, that transports Zn(2+) from the endoplasmic reticulum/Golgi apparatus to the cytosol. Transport is stimulated by growth factors, such as EGF, and Ca(2+), as well as by exogenous Zn(2+); Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily. (469 aa)
SLC39A4Zinc transporter ZIP4; Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability (By similarity). (647 aa)
SLC39A9Zinc transporter ZIP9; May act as a zinc-influx transporter. (307 aa)
SLC39A13Zinc transporter ZIP13; Acts as a zinc-influx transporter. Belongs to the ZIP transporter (TC 2.A.5) family. (371 aa)
SLC39A1Zinc transporter ZIP1; Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells. (324 aa)
SLC39A2Zinc transporter ZIP2; Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence of albumin. May also transport other divalent cations. May be important in contact inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis. (309 aa)
SLC39A12Zinc transporter ZIP12; Acts as a zinc-influx transporter (Potential). May be partly involved in the outbreak of schizophrenia; Belongs to the ZIP transporter (TC 2.A.5) family. (691 aa)
SLC39A14Zinc transporter ZIP14; Broad-scope metal ion transporter with a preference for zinc uptake. Also mediates cellular uptake of nontransferrin-bound iron. (492 aa)
SLC39A8Zinc transporter ZIP8; Acts as a manganese and zinc influx transporter. Plays a role in manganese reabsorption in the proximal tubule of the kidney and in manganese uptake into the brain ; Belongs to the ZIP transporter (TC 2.A.5) family. (460 aa)
SLC39A10Zinc transporter ZIP10; May act as a zinc-influx transporter. Belongs to the ZIP transporter (TC 2.A.5) family. (831 aa)
SLC39A11Zinc transporter ZIP11; Functions as a cellular zinc transporter. (342 aa)
K7EQS6_HUMANUncharacterized protein. (105 aa)
SLC39A5Zinc transporter ZIP5; May play a role in polarized cells by carrying out serosal- to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera. Seems to play a central role in controlling organismal zinc status (By similarity). (540 aa)
SLC39A6Zinc transporter ZIP6; May act as a zinc-influx transporter. Belongs to the ZIP transporter (TC 2.A.5) family. (755 aa)
SLC39A3Zinc transporter ZIP3; Acts as a zinc-influx transporter. (314 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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