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| MDH2 | Malate dehydrogenase, mitochondrial; Malate dehydrogenase 2. (338 aa) | ||||
| LDHAL6A | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. (332 aa) | ||||
| LDHAL6B | Lactate dehydrogenase A like 6B. (381 aa) | ||||
| PKM | Pyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation a [...] (531 aa) | ||||
| LDHC | L-lactate dehydrogenase C chain; Possible role in sperm motility. (332 aa) | ||||
| LDHA | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. (361 aa) | ||||
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LDHA | LDHAL6A | ENSP00000445175 | ENSP00000280706 | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. | 0.799 |
| LDHA | LDHC | ENSP00000445175 | ENSP00000437783 | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. | L-lactate dehydrogenase C chain; Possible role in sperm motility. | 0.985 |
| LDHA | MDH2 | ENSP00000445175 | ENSP00000327070 | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. | Malate dehydrogenase, mitochondrial; Malate dehydrogenase 2. | 0.434 |
| LDHA | PKM | ENSP00000445175 | ENSP00000320171 | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. | Pyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation a [...] | 0.997 |
| LDHAL6A | LDHA | ENSP00000280706 | ENSP00000445175 | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. | 0.799 |
| LDHAL6A | LDHC | ENSP00000280706 | ENSP00000437783 | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. | L-lactate dehydrogenase C chain; Possible role in sperm motility. | 0.786 |
| LDHAL6A | MDH2 | ENSP00000280706 | ENSP00000327070 | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. | Malate dehydrogenase, mitochondrial; Malate dehydrogenase 2. | 0.505 |
| LDHAL6A | PKM | ENSP00000280706 | ENSP00000320171 | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. | Pyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation a [...] | 0.986 |
| LDHAL6B | PKM | ENSP00000302393 | ENSP00000320171 | Lactate dehydrogenase A like 6B. | Pyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation a [...] | 0.982 |
| LDHC | LDHA | ENSP00000437783 | ENSP00000445175 | L-lactate dehydrogenase C chain; Possible role in sperm motility. | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. | 0.985 |
| LDHC | LDHAL6A | ENSP00000437783 | ENSP00000280706 | L-lactate dehydrogenase C chain; Possible role in sperm motility. | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. | 0.786 |
| LDHC | PKM | ENSP00000437783 | ENSP00000320171 | L-lactate dehydrogenase C chain; Possible role in sperm motility. | Pyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation a [...] | 0.983 |
| MDH2 | LDHA | ENSP00000327070 | ENSP00000445175 | Malate dehydrogenase, mitochondrial; Malate dehydrogenase 2. | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. | 0.434 |
| MDH2 | LDHAL6A | ENSP00000327070 | ENSP00000280706 | Malate dehydrogenase, mitochondrial; Malate dehydrogenase 2. | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. | 0.505 |
| MDH2 | PKM | ENSP00000327070 | ENSP00000320171 | Malate dehydrogenase, mitochondrial; Malate dehydrogenase 2. | Pyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation a [...] | 0.829 |
| PKM | LDHA | ENSP00000320171 | ENSP00000445175 | Pyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation a [...] | Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family. | 0.997 |
| PKM | LDHAL6A | ENSP00000320171 | ENSP00000280706 | Pyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation a [...] | L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed. | 0.986 |
| PKM | LDHAL6B | ENSP00000320171 | ENSP00000302393 | Pyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation a [...] | Lactate dehydrogenase A like 6B. | 0.982 |
| PKM | LDHC | ENSP00000320171 | ENSP00000437783 | Pyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation a [...] | L-lactate dehydrogenase C chain; Possible role in sperm motility. | 0.983 |
| PKM | MDH2 | ENSP00000320171 | ENSP00000327070 | Pyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation a [...] | Malate dehydrogenase, mitochondrial; Malate dehydrogenase 2. | 0.829 |