STRINGSTRING
GLS2 GLS2 CDO1 CDO1 PHYKPL PHYKPL ARG1 ARG1 IYD IYD TPH2 TPH2 SERINC1 SERINC1 PYCR3 PYCR3 MPST MPST TST TST TXN2 TXN2 CARNMT1 CARNMT1 GNMT GNMT SLC25A13 SLC25A13 ASNS ASNS LIPT1 LIPT1 GRHPR GRHPR HAAO HAAO PSME4 PSME4 SLC44A1 SLC44A1 BCKDHB BCKDHB HIBADH HIBADH TPO TPO LOC100856577 LOC100856577 DDC DDC IL4I1 IL4I1 AASS AASS PSMB2 PSMB2 PSMD5 PSMD5 UROC1 UROC1 DDO DDO AMD1 AMD1 PSMC2 PSMC2 GLUD1-2 GLUD1-2 SLC36A4 SLC36A4 ETHE1 ETHE1 DHTKD1 DHTKD1 BCKDHA BCKDHA AANAT AANAT DCT DCT PSMC4 PSMC4 KYNU KYNU LIPT2 LIPT2 SLC25A10 SLC25A10 HAO1 HAO1 SLC25A15 SLC25A15 SMOX SMOX SNRPF SNRPF PRODH2 PRODH2 PSMF1 PSMF1 PDHX PDHX PAH PAH PDHB PDHB AHCY AHCY AADAT AADAT MCCC2 MCCC2 PSMD9 PSMD9 CHDH CHDH GOT2 GOT2 ALDH18A1 ALDH18A1 TDO2 TDO2 PSMC3 PSMC3 CKMT2 CKMT2 ENOPH1 ENOPH1 BHMT BHMT BHMT2 BHMT2 IVD IVD DMGDH DMGDH HOGA1 HOGA1 GOT1 GOT1 HIBCH HIBCH SERINC3 SERINC3 GLS GLS OCA2 OCA2 PSMD14 PSMD14 MTRR MTRR PSPH PSPH SERINC2 SERINC2 PSMB5 PSMB5 CARNS1 CARNS1 MCCC1 MCCC1 FTCD FTCD PSME1 PSME1 PSMA7 PSMA7 PSMD4 PSMD4 PSMD2 PSMD2 ACADSB ACADSB PSMB4 PSMB4 PSMC5 PSMC5 LOC607355 LOC607355 OAZ3 OAZ3 ADO ADO CKMT1A CKMT1A SERINC4 SERINC4 PSMA6 PSMA6 ECHS1 ECHS1 ALDH9A1 ALDH9A1 DUOX2 DUOX2 DUOX1 DUOX1 SQOR SQOR RIMKLB RIMKLB FAH FAH DLAT DLAT OTC OTC PCBD1 PCBD1 NAGS NAGS FMO1 FMO1 SLC5A5 SLC5A5 HDC HDC SLC3A2 SLC3A2 KMO KMO SLC6A12 SLC6A12 PSMB6 PSMB6 ASRGL1 ASRGL1 PYCR2 PYCR2 AGMAT AGMAT PSMD3 PSMD3 HSD17B10 HSD17B10 PNMT PNMT PSMB3 PSMB3 MRI1 MRI1 BCKDK BCKDK GSTZ1 GSTZ1 PSMC1 PSMC1 NDUFAB1 NDUFAB1 CRYM CRYM PSMA8 PSMA8 SLC6A7 SLC6A7 SHMT1 SHMT1 ASPG ASPG PSMD11 PSMD11 PIPOX PIPOX NMRAL1 NMRAL1 SLC6A8 SLC6A8 SGSM2 SGSM2 ASPA ASPA OAZ1 OAZ1 TMLHE TMLHE DBH DBH PSMA5 PSMA5 SLC7A5 SLC7A5 GCSH GCSH DBT DBT PSMB10 PSMB10 CTH CTH LOC608055 LOC608055 AMT AMT PSMB1 PSMB1 ODC1 ODC1 RIMKLA RIMKLA TAT TAT PSMD10 PSMD10 ASMT ASMT OAT OAT PSMD13 PSMD13 ACAT1 ACAT1 PSMD12 PSMD12 SLC25A2 SLC25A2 RIDA RIDA PSMB9 PSMB9 OAZ2 OAZ2 BBOX1 BBOX1 SLC25A21 SLC25A21 LOC100687259 LOC100687259 ALDH6A1 ALDH6A1 HYKK HYKK ALDH4A1 ALDH4A1 SRM SRM J9P2T7_CANLF J9P2T7_CANLF CBS CBS PSMD7 PSMD7 CKM CKM PSMA3 PSMA3 IDO2 IDO2 TPH1 TPH1 LIAS LIAS SCLY SCLY ENSCAFP00000047134 ENSCAFP00000047134 ASS1 ASS1 GCDH GCDH SERINC5 SERINC5 AZIN1 AZIN1 NAALAD2 NAALAD2 ACAD8 ACAD8 NQO1 NQO1 GADL1 GADL1 PSMA4 PSMA4 HPD HPD CPS1 CPS1 TSTD1 TSTD1 SMS SMS PSMC6 PSMC6 MTR MTR GLDC GLDC FOLH1 FOLH1 PHGDH PHGDH HAL HAL AGXT2 AGXT2 SDSL SDSL GATM GATM DIO1 DIO1 MTAP MTAP GLUD1 GLUD1 ADI1 ADI1 PSMB7 PSMB7 PDHA1 PDHA1 NAT8L NAT8L ARG2 ARG2 KYAT1 KYAT1 LOC100855679 LOC100855679 PSMA2 PSMA2 AUH AUH BCAT2 BCAT2 HGD HGD PSME2 PSME2 AMACR AMACR LOC477562 LOC477562 AZIN2 AZIN2 SLC25A12 SLC25A12 QDPR QDPR PPM1K PPM1K DLST DLST SARDH SARDH CKB-2 CKB-2 ALDH7A1 ALDH7A1 IDO1 IDO1 MAT1A MAT1A PYCR1 PYCR1 PSAT1 PSAT1 SLC6A11 SLC6A11 PSMD1 PSMD1 BCAT1 BCAT1 TXNRD1 TXNRD1 OGDH OGDH SUOX SUOX DAO DAO PSMA1 PSMA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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GLS2Glutaminase 2. (603 aa)
CDO1Cysteine dioxygenase. (200 aa)
PHYKPL5-phosphohydroxy-L-lysine phospho-lyase. (583 aa)
ARG1Arginase. (322 aa)
IYDIodotyrosine deiodinase. (290 aa)
TPH2Tryptophan hydroxylase 2. (491 aa)
SERINC1Serine incorporator 1. (453 aa)
PYCR3Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (288 aa)
MPSTMercaptopyruvate sulfurtransferase. (288 aa)
TSTSulfurtransferase. (361 aa)
TXN2Thioredoxin 2. (163 aa)
CARNMT1Carnosine N-methyltransferase 1. (411 aa)
GNMTGlycine N-methyltransferase. (295 aa)
SLC25A13Solute carrier family 25 member 13; Belongs to the mitochondrial carrier (TC 2.A.29) family. (676 aa)
ASNSAsparagine synthetase [glutamine-hydrolyzing]. (561 aa)
LIPT1Lipoyltransferase 1. (381 aa)
GRHPRGlyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (328 aa)
HAAO3-hydroxyanthranilate 3,4-dioxygenase. (259 aa)
PSME4Proteasome activator subunit 4. (1762 aa)
SLC44A1Solute carrier family 44 member 1; Belongs to the CTL (choline transporter-like) family. (723 aa)
BCKDHBBranched chain keto acid dehydrogenase E1 subunit beta. (423 aa)
HIBADH3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (336 aa)
TPOThyroid peroxidase; Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). Belongs to the peroxidase family. XPO subfamily. (944 aa)
LOC1008565771,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (139 aa)
DDCDopa decarboxylase. (506 aa)
IL4I1Interleukin 4 induced 1. (579 aa)
AASSAminoadipate-semialdehyde synthase. (920 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMD5Uncharacterized protein. (500 aa)
UROC1Urocanate hydratase 1. (735 aa)
DDOD-aspartate oxidase. (351 aa)
AMD1Adenosylmethionine decarboxylase 1. (265 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
GLUD1-2Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (490 aa)
SLC36A4Solute carrier family 36 member 4. (485 aa)
ETHE1ETHE1 persulfide dioxygenase. (254 aa)
DHTKD1Dehydrogenase E1 and transketolase domain containing 1. (920 aa)
BCKDHA2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (563 aa)
AANATArylalkylamine N-acetyltransferase. (207 aa)
DCTUncharacterized protein. (548 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
KYNUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (489 aa)
LIPT2Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family. (231 aa)
SLC25A10Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (446 aa)
HAO1Hydroxyacid oxidase 1. (370 aa)
SLC25A15Solute carrier family 25 member 15; Belongs to the mitochondrial carrier (TC 2.A.29) family. (301 aa)
SMOXSpermine oxidase. (585 aa)
SNRPFAmidohydrolase domain containing 1. (451 aa)
PRODH2Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (460 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (501 aa)
PAHPhenylalanine hydroxylase. (581 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
AHCYAdenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. (425 aa)
AADATAminoadipate aminotransferase. (551 aa)
MCCC2Methylcrotonoyl-CoA carboxylase 2. (563 aa)
PSMD9Proteasome 26S subunit, non-ATPase 9. (223 aa)
CHDHCholine dehydrogenase. (703 aa)
GOT2Aspartate aminotransferase. (430 aa)
ALDH18A1Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (795 aa)
TDO2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
CKMT2Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family. (437 aa)
ENOPH1Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (366 aa)
BHMTBetaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism. (407 aa)
BHMT2Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism. (363 aa)
IVDIsovaleryl-CoA dehydrogenase. (426 aa)
DMGDHDimethylglycine dehydrogenase. (832 aa)
HOGA14-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family. (327 aa)
GOT1Aspartate aminotransferase. (413 aa)
HIBCH3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (382 aa)
SERINC3Serine incorporator 3. (473 aa)
GLSGlutaminase. (754 aa)
OCA2OCA2 melanosomal transmembrane protein. (777 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (308 aa)
MTRR5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (704 aa)
PSPHPhosphoserine phosphatase. (225 aa)
SERINC2Serine incorporator 2. (467 aa)
PSMB5Proteasome subunit beta. (263 aa)
CARNS1Carnosine synthase 1. (925 aa)
MCCC1Methylcrotonoyl-CoA carboxylase 1. (725 aa)
FTCDFormimidoyltransferase cyclodeaminase. (541 aa)
PSME1Proteasome activator subunit 1. (249 aa)
PSMA7Proteasome endopeptidase complex. (178 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (377 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
ACADSBAcyl-CoA dehydrogenase short/branched chain. (514 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
LOC607355Aminotran_5 domain-containing protein. (463 aa)
OAZ3Uncharacterized protein. (234 aa)
ADO2-aminoethanethiol dioxygenase. (270 aa)
CKMT1AUncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (417 aa)
SERINC4Serine incorporator 4. (517 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (291 aa)
ALDH9A1Aldehyde dehydrogenase 9 family member A1; Belongs to the aldehyde dehydrogenase family. (509 aa)
DUOX2Dual oxidase 2. (1519 aa)
DUOX1Dual oxidase 1; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain. (1551 aa)
SQORPyr_redox_2 domain-containing protein. (450 aa)
RIMKLBRibosomal modification protein rimK like family member B. (386 aa)
FAHFumarylacetoacetase. (418 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (647 aa)
OTCOrnithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa)
PCBD1Pterin-4 alpha-carbinolamine dehydratase 1. (103 aa)
NAGSN-acetylglutamate synthase. (537 aa)
FMO1Dimethylaniline monooxygenase [N-oxide-forming] 1; This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. (532 aa)
SLC5A5Solute carrier family 5 member 5; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (642 aa)
HDCHistidine decarboxylase. (663 aa)
SLC3A2Aamy domain-containing protein. (533 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (477 aa)
SLC6A12Sodium- and chloride-dependent betaine transporter; Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily. (614 aa)
PSMB6Proteasome subunit beta. (239 aa)
ASRGL1Asparaginase like 1. (316 aa)
PYCR2Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa)
AGMATAgmatinase; Belongs to the arginase family. (352 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
HSD17B10Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
PNMTPhenylethanolamine N-methyltransferase. (452 aa)
PSMB3Proteasome subunit beta. (205 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (368 aa)
BCKDKProtein-serine/threonine kinase. (528 aa)
GSTZ1Glutathione S-transferase zeta 1; Belongs to the GST superfamily. (217 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (154 aa)
CRYMCrystallin mu. (314 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
SLC6A7Solute carrier family 6 member 7. (633 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
ASPGAsparaginase. (849 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PIPOXPipecolic acid and sarcosine oxidase. (392 aa)
NMRAL1NmrA like redox sensor 1. (416 aa)
SLC6A8Solute carrier family 6 member 8. (498 aa)
SGSM2Small G protein signaling modulator 2. (1256 aa)
ASPAAspartoacylase. (313 aa)
OAZ1Ornithine decarboxylase antizyme 1. (182 aa)
TMLHETrimethyllysine hydroxylase, epsilon. (421 aa)
DBHSoluble dopamine beta-hydroxylase; Conversion of dopamine to noradrenaline. (625 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
SLC7A5Uncharacterized protein. (488 aa)
GCSHGlycine cleavage system protein H. (306 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (482 aa)
PSMB10Proteasome subunit beta. (272 aa)
CTHCystathionine gamma-lyase. (547 aa)
LOC608055D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (572 aa)
AMTAminomethyltransferase, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (403 aa)
PSMB1Proteasome subunit beta. (241 aa)
ODC1Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (448 aa)
RIMKLARibosomal modification protein rimK like family member A. (391 aa)
TATTyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (454 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
ASMTAcetylserotonin O-methyltransferase. (343 aa)
OATOrnithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (415 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (376 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (433 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
SLC25A2Solute carrier family 25 member 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (301 aa)
RIDAReactive intermediate imine deaminase A homolog. (336 aa)
PSMB9Proteasome subunit beta. (209 aa)
OAZ2Uncharacterized protein. (183 aa)
BBOX1Gamma-butyrobetaine hydroxylase 1. (491 aa)
SLC25A21Solute carrier family 25 member 21; Belongs to the mitochondrial carrier (TC 2.A.29) family. (299 aa)
LOC100687259AAA domain-containing protein; Belongs to the AAA ATPase family. (365 aa)
ALDH6A1Aldehyde dehydrogenase 6 family member A1. (543 aa)
HYKKHydroxylysine kinase. (376 aa)
ALDH4A1Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (564 aa)
SRMSpermidine synthase; Belongs to the spermidine/spermine synthase family. (351 aa)
J9P2T7_CANLFUncharacterized protein. (461 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (549 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
CKMCreatine kinase M-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa; Belongs to the ATP:guanido phosphotransferase family. (429 aa)
PSMA3Proteasome endopeptidase complex. (257 aa)
IDO2Indoleamine 2,3-dioxygenase 2. (438 aa)
TPH1Tryptophan hydroxylase 1. (452 aa)
LIASLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (385 aa)
SCLYSelenocysteine lyase. (450 aa)
ENSCAFP00000047134Proteasome endopeptidase complex. (216 aa)
ASS1Argininosuccinate synthase 1. (526 aa)
GCDHGlutaryl-CoA dehydrogenase. (531 aa)
SERINC5Serine incorporator 5. (483 aa)
AZIN1Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (447 aa)
NAALAD2N-acetylated alpha-linked acidic dipeptidase 2. (803 aa)
ACAD8Acyl-CoA dehydrogenase family member 8. (442 aa)
NQO1NAD(P)H quinone dehydrogenase 1. (448 aa)
GADL1Glutamate decarboxylase like 1. (716 aa)
PSMA4Proteasome subunit alpha 4. (290 aa)
HPD4-hydroxyphenylpyruvate dioxygenase; Belongs to the 4HPPD family. (400 aa)
CPS1Carbamoyl-phosphate synthase 1. (1532 aa)
TSTD1Thiosulfate sulfurtransferase like domain containing 1. (161 aa)
SMSSpermine synthase. (379 aa)
PSMC6AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
MTR5-methyltetrahydrofolate-homocysteine methyltransferase. (1330 aa)
GLDCGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1032 aa)
FOLH1Uncharacterized protein. (758 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (646 aa)
HALHistidine ammonia-lyase; Belongs to the PAL/histidase family. (667 aa)
AGXT2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (541 aa)
SDSLSerine dehydratase like. (396 aa)
GATMUncharacterized protein. (447 aa)
DIO1Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney. (244 aa)
MTAPMethylthioadenosine phosphorylase. (356 aa)
GLUD1ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (946 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (159 aa)
PSMB7Proteasome subunit beta. (315 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (405 aa)
NAT8LN-acetyltransferase 8 like. (323 aa)
ARG2Arginase. (384 aa)
KYAT1Kynurenine aminotransferase 1. (541 aa)
LOC100855679Aminotran_5 domain-containing protein. (537 aa)
PSMA2Proteasome subunit alpha type. (295 aa)
AUHAU RNA binding methylglutaconyl-CoA hydratase. (344 aa)
BCAT2Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (592 aa)
HGDHomogentisate 1,2-dioxygenase. (462 aa)
PSME2Proteasome activator subunit 2. (253 aa)
AMACRSolute carrier family 45 member 2. (647 aa)
LOC477562Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (653 aa)
AZIN2Antizyme inhibitor 2. (523 aa)
SLC25A12Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (747 aa)
QDPRQuinoid dihydropteridine reductase. (317 aa)
PPM1KProtein phosphatase, Mg2+/Mn2+ dependent 1K. (381 aa)
DLSTDihydrolipoamide S-succinyltransferase. (652 aa)
SARDHSarcosine dehydrogenase. (943 aa)
CKB-2Creatine kinase B-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa; Belongs to the ATP:guanido phosphotransferase family. (377 aa)
ALDH7A1Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family. (539 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (421 aa)
MAT1AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (428 aa)
PYCR1Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (430 aa)
PSAT1Phosphoserine aminotransferase. (391 aa)
SLC6A11Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (669 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
BCAT1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (470 aa)
TXNRD1Thioredoxin reductase 1; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (744 aa)
OGDHTransket_pyr domain-containing protein. (998 aa)
SUOXSulfite oxidase. (733 aa)
DAOD-amino acid oxidase. (376 aa)
PSMA1Proteasome subunit alpha type. (267 aa)
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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