(4 nodes) (2011) Progress with schistosome transgenesis. network (Canis lupus familiaris)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Known Interactions

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Predicted Interactions

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protein homology

Your Input:
	CTSB	Cathepsin B; Belongs to the peptidase C1 family. (404 aa)
	CTSD	Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family. (410 aa)
	GP2	Pancreatic secretory granule membrane major glycoprotein GP2. (519 aa)
	TERT	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1253 aa)

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTSB	CTSD	ENSCAFP00000059573	ENSCAFP00000014791	Cathepsin B; Belongs to the peptidase C1 family.	Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family.	0.931
CTSB	GP2	ENSCAFP00000059573	ENSCAFP00000026630	Cathepsin B; Belongs to the peptidase C1 family.	Pancreatic secretory granule membrane major glycoprotein GP2.	0.461
CTSD	CTSB	ENSCAFP00000014791	ENSCAFP00000059573	Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family.	Cathepsin B; Belongs to the peptidase C1 family.	0.931
GP2	CTSB	ENSCAFP00000026630	ENSCAFP00000059573	Pancreatic secretory granule membrane major glycoprotein GP2.	Cathepsin B; Belongs to the peptidase C1 family.	0.461