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M3XLW0_MUSPF M3XLW0_MUSPF ATG4B ATG4B M3XML9_MUSPF M3XML9_MUSPF ATG12 ATG12 PIK3C3 PIK3C3 LOC101681938 LOC101681938 M3XSF2_MUSPF M3XSF2_MUSPF TTC14 TTC14 M3XV19_MUSPF M3XV19_MUSPF ATG2B ATG2B ATG4A ATG4A M3XYF5_MUSPF M3XYF5_MUSPF ATG16L1 ATG16L1 ATG13 ATG13 M3Y3L0_MUSPF M3Y3L0_MUSPF GABARAPL1 GABARAPL1 ATG4D ATG4D M3Y6T5_MUSPF M3Y6T5_MUSPF ATG101 ATG101 ATG9B ATG9B ATG4C ATG4C ATG10 ATG10 ATG5 ATG5 GABARAPL2 GABARAPL2 BECN1 BECN1 PPP2CA PPP2CA PPP2CB PPP2CB M3YFV0_MUSPF M3YFV0_MUSPF GABARAP GABARAP RPTOR RPTOR ATG2A ATG2A ENSMPUP00000014058 ENSMPUP00000014058 WIPI1 WIPI1 MLST8 MLST8 BECN2 BECN2 MTOR MTOR M3YYR0_MUSPF M3YYR0_MUSPF WIPI2 WIPI2 ATG7 ATG7 ULK3 ULK3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
M3XLW0_MUSPFDUF3543 domain-containing protein. (669 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (393 aa)
M3XML9_MUSPFAutophagy-related protein 3. (314 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
LOC101681938Protein kinase domain-containing protein. (490 aa)
M3XSF2_MUSPFUncharacterized protein. (124 aa)
TTC14Tetratricopeptide repeat domain 14. (769 aa)
M3XV19_MUSPFUncharacterized protein. (123 aa)
ATG2BAutophagy related 2B. (2078 aa)
ATG4ACysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (398 aa)
M3XYF5_MUSPFUncharacterized protein. (341 aa)
ATG16L1Autophagy related 16 like 1. (623 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
M3Y3L0_MUSPFUncharacterized protein. (99 aa)
GABARAPL1GABA type A receptor associated protein like 1. (123 aa)
ATG4DCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (443 aa)
M3Y6T5_MUSPFAutophagy-related protein 3. (293 aa)
ATG101Autophagy related 101. (218 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (869 aa)
ATG4CCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (458 aa)
ATG10Autophagy related 10. (216 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
GABARAPL2GABA type A receptor associated protein like 2. (120 aa)
BECN1Beclin 1. (448 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PPP2CBSerine/threonine-protein phosphatase. (284 aa)
M3YFV0_MUSPFProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
GABARAPGABA type A receptor-associated protein. (122 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1244 aa)
ATG2AAutophagy related 2A. (1930 aa)
ENSMPUP00000014058annotation not available (213 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (479 aa)
MLST8MTOR associated protein, LST8 homolog. (328 aa)
BECN2Beclin 2. (437 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2552 aa)
M3YYR0_MUSPFAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (839 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (436 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (788 aa)
ULK3Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (472 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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