STRINGSTRING
SAMD4A SAMD4A EXOSC10 EXOSC10 SLFN5 SLFN5 ENTPD2 ENTPD2 RNASEH2A RNASEH2A DNASE2 DNASE2 CNOT7 CNOT7 CNOT8 CNOT8 CTIF CTIF AGO1 AGO1 NCBP1 NCBP1 UPB1 UPB1 CNOT6 CNOT6 DCP2 DCP2 POP1 POP1 NT5DC4 NT5DC4 PNLDC1 PNLDC1 EXOG EXOG NUDT9 NUDT9 LSM7 LSM7 DDX5 DDX5 DCP1A DCP1A APOBEC2 APOBEC2 SKIV2L SKIV2L DXO DXO NBAS NBAS ZC3H4 ZC3H4 PDE4A PDE4A SUPV3L1 SUPV3L1 ISG20 ISG20 PDE8B PDE8B ENDOG ENDOG NT5C1A NT5C1A DHX34 DHX34 AGO4 AGO4 ACOT7 ACOT7 CNOT11 CNOT11 METTL14 METTL14 XRN2 XRN2 EIF4A3 EIF4A3 SARM1 SARM1 ZC3H12A ZC3H12A MRTO4 MRTO4 FBH1 FBH1 APOBEC1 APOBEC1 DNPH1 DNPH1 PABPN1L PABPN1L MTREX MTREX TTC37 TTC37 DNA2 DNA2 SWT1 SWT1 SSB SSB DFFB DFFB REXO4 REXO4 ZPR1 ZPR1 UPP1 UPP1 PAN2 PAN2 DNASE1 DNASE1 EDC4 EDC4 SAMHD1 SAMHD1 PNPT1 PNPT1 MUS81 MUS81 ADAL ADAL SMG8 SMG8 LRPPRC LRPPRC PDE8A PDE8A FEN1 FEN1 NUDT12 NUDT12 PYM1 PYM1 ENTPD1 ENTPD1 CNOT3 CNOT3 ENPP3 ENPP3 RNASEH2B RNASEH2B UPF3A UPF3A NUDT3 NUDT3 TENT2 TENT2 TREX2 TREX2 MTPAP MTPAP TTC38 TTC38 ZHX2 ZHX2 HINT1 HINT1 M3WS38_FELCA M3WS38_FELCA DIS3L DIS3L ZCCHC7 ZCCHC7 NUDT7 NUDT7 ETF1 ETF1 CNP CNP NOCT NOCT UPF2 UPF2 CSDE1 CSDE1 HPRT1-2 HPRT1-2 LOC101082293 LOC101082293 NUDT4 NUDT4 TREX1 TREX1 CNOT1 CNOT1 WDR82 WDR82 POLR2G POLR2G PDE12 PDE12 EXOSC2 EXOSC2 SMG6 SMG6 NANOS2 NANOS2 MAGOH MAGOH ZFP36L1 ZFP36L1 EXOSC9 EXOSC9 EXOSC7 EXOSC7 NUDT17 NUDT17 NUDT15 NUDT15 ATM ATM FHIT FHIT NT5C2 NT5C2 DNASE1L3 DNASE1L3 DCTPP1 DCTPP1 UPF3B UPF3B FITM2 FITM2 DUT DUT ERN2 ERN2 ENPP4 ENPP4 ENTPD3 ENTPD3 ADA2 ADA2 AICDA AICDA SMG5 SMG5 SND1 SND1 APEX1 APEX1 ENTPD6 ENTPD6 EXOSC3 EXOSC3 RIDA RIDA THRAP3 THRAP3 EXOSC5 EXOSC5 NT5C NT5C CDA CDA NBDY NBDY DNASE2B DNASE2B SAMD4B SAMD4B DPYD DPYD EXOSC4 EXOSC4 ENSFCAP00000035681 ENSFCAP00000035681 PDE5A PDE5A CNOT9 CNOT9 ENSFCAP00000036935 ENSFCAP00000036935 PATL1 PATL1 CNOT2 CNOT2 PELO PELO SIDT2 SIDT2 ENSFCAP00000039364 ENSFCAP00000039364 URAD URAD LSM1 LSM1 RBM8A RBM8A DICER1 DICER1 PAN3 PAN3 SMG9 SMG9 ENSFCAP00000040149 ENSFCAP00000040149 LOC101082293-2 LOC101082293-2 ITPA ITPA ENTPD4 ENTPD4 MLYCD MLYCD NUDT13 NUDT13 PABPC1 PABPC1 SMG1 SMG1 CDADC1 CDADC1 RNASET2 RNASET2 NUDT19 NUDT19 LSM2 LSM2 NUDT18 NUDT18 LSM4 LSM4 PARN PARN ZFP36L2 ZFP36L2 DIS3 DIS3 PDE2A PDE2A EIF3E EIF3E SMG7 SMG7 RC3H2 RC3H2 NUDT5 NUDT5 EDC3 EDC3 NUDT16 NUDT16 ENTPD8 ENTPD8 ENSFCAP00000047437 ENSFCAP00000047437 ZFP36 ZFP36 RC3H1 RC3H1 XRN1 XRN1 EXOSC1 EXOSC1 EXOSC6 EXOSC6 LIN28B LIN28B NT5M NT5M PDE9A PDE9A ENTPD5 ENTPD5 CNOT10 CNOT10 PDE4C PDE4C ENSFCAP00000051025 ENSFCAP00000051025 OPRD1 OPRD1 NUDT1 NUDT1 CNOT6L CNOT6L SMPDL3A SMPDL3A THRA THRA EXOSC8 EXOSC8 DIS3L2 DIS3L2 RNASEH2C RNASEH2C AGO3 AGO3 DNASE1L1 DNASE1L1 DERA DERA PNRC2 PNRC2 DFFA DFFA HELZ2 HELZ2 KHSRP KHSRP DNASE1L2 DNASE1L2 FOXL2 FOXL2 ENTPD7 ENTPD7 DCP1B DCP1B ADA ADA LRRC27 LRRC27 UPF1 UPF1 RNASEH1 RNASEH1 APOBEC3Z3 APOBEC3Z3 PDE4D PDE4D GDA GDA HPRT1 HPRT1 ENSFCAP00000060005 ENSFCAP00000060005 ACAT1 ACAT1 NT5E NT5E ENPP1 ENPP1 PDE4B PDE4B MGAT1 MGAT1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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SAMD4ASterile alpha motif domain containing 4A. (760 aa)
EXOSC10Exosome component 10. (887 aa)
SLFN5Schlafen family member 5. (888 aa)
ENTPD2Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (495 aa)
RNASEH2ARibonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (299 aa)
DNASE2Deoxyribonuclease 2, lysosomal. (359 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
CNOT8CCR4-NOT transcription complex subunit 8. (292 aa)
CTIFCap binding complex dependent translation initiation factor. (616 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (857 aa)
NCBP1Nuclear cap binding protein subunit 1. (789 aa)
UPB1Beta-ureidopropionase 1. (384 aa)
CNOT6CCR4-NOT transcription complex subunit 6. (557 aa)
DCP2Decapping mRNA 2. (422 aa)
POP1POP1 homolog, ribonuclease P/MRP subunit. (959 aa)
NT5DC45'-nucleotidase domain containing 4. (427 aa)
PNLDC1PARN like, ribonuclease domain containing 1. (531 aa)
EXOGExo/endonuclease G. (368 aa)
NUDT9Nudix hydrolase 9. (350 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
DCP1ADecapping mRNA 1A. (580 aa)
APOBEC2Apolipoprotein B mRNA editing enzyme catalytic subunit 2. (224 aa)
SKIV2LSki2 like RNA helicase. (1246 aa)
DXODecapping exoribonuclease. (397 aa)
NBASNeuroblastoma amplified sequence. (2371 aa)
ZC3H4Zinc finger CCCH-type containing 4. (1274 aa)
PDE4APhosphodiesterase. (868 aa)
SUPV3L1Suv3 like RNA helicase. (807 aa)
ISG20Interferon stimulated exonuclease gene 20. (171 aa)
PDE8BPhosphodiesterase. (890 aa)
ENDOGEndonuclease. (298 aa)
NT5C1A5'-nucleotidase, cytosolic IA. (348 aa)
DHX34DExH-box helicase 34. (1135 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (861 aa)
ACOT7Acyl-CoA thioesterase 7. (445 aa)
CNOT11CCR4-NOT transcription complex subunit 11. (513 aa)
METTL14Methyltransferase like 14; Belongs to the MT-A70-like family. (456 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (950 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
SARM1Sterile alpha and TIR motif containing 1. (724 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (582 aa)
MRTO4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (238 aa)
FBH1F-box DNA helicase 1. (1065 aa)
APOBEC1Apolipoprotein B mRNA editing enzyme catalytic subunit 1. (236 aa)
DNPH12'-deoxynucleoside 5'-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases. (169 aa)
PABPN1LPoly(A) binding protein nuclear 1 like, cytoplasmic. (277 aa)
MTREXMtr4 exosome RNA helicase. (1042 aa)
TTC37Tetratricopeptide repeat domain 37. (1565 aa)
DNA2DNA replication helicase/nuclease 2. (1061 aa)
SWT1SWT1 RNA endoribonuclease homolog. (903 aa)
SSBSmall RNA binding exonuclease protection factor La. (406 aa)
DFFBDNA fragmentation factor subunit beta. (647 aa)
REXO4REX4 homolog, 3'-5' exonuclease. (544 aa)
ZPR1ZPR1 zinc finger. (459 aa)
UPP1Uridine phosphorylase 1. (354 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1202 aa)
DNASE1Deoxyribonuclease; Belongs to the DNase I family. (282 aa)
EDC4Enhancer of mRNA decapping 4. (1402 aa)
SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (627 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (784 aa)
MUS81MUS81 structure-specific endonuclease subunit. (612 aa)
ADALAdenosine deaminase like. (356 aa)
SMG8SMG8 nonsense mediated mRNA decay factor. (993 aa)
LRPPRCLeucine rich pentatricopeptide repeat containing. (1394 aa)
PDE8APhosphodiesterase. (836 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
NUDT12Nudix hydrolase 12. (477 aa)
PYM1PYM homolog 1, exon junction complex associated factor. (203 aa)
ENTPD1Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (510 aa)
CNOT3CCR4-NOT transcription complex subunit 3. (746 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase 3. (874 aa)
RNASEH2BRibonuclease H2 subunit B. (302 aa)
UPF3AUPF3A regulator of nonsense mediated mRNA decay. (478 aa)
NUDT3Nudix hydrolase 3. (172 aa)
TENT2Terminal nucleotidyltransferase 2. (484 aa)
TREX2Three prime repair exonuclease 2. (236 aa)
MTPAPMitochondrial poly(A) polymerase. (584 aa)
TTC38Tetratricopeptide repeat domain 38. (469 aa)
ZHX2Zinc fingers and homeoboxes 2. (838 aa)
HINT1HIT domain-containing protein. (126 aa)
M3WS38_FELCAdUTPase domain-containing protein. (141 aa)
DIS3LDIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1027 aa)
ZCCHC7Zinc finger CCHC-type containing 7. (545 aa)
NUDT7Nudix hydrolase 7. (238 aa)
ETF1eRF1_1 domain-containing protein. (437 aa)
CNP2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family. (420 aa)
NOCTNocturnin. (431 aa)
UPF2UPF2 regulator of nonsense mediated mRNA decay. (1272 aa)
CSDE1Cold shock domain containing E1. (844 aa)
HPRT1-2Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
LOC101082293Nudix hydrolase domain-containing protein. (164 aa)
NUDT4Nudix hydrolase domain-containing protein. (181 aa)
TREX1Three prime repair exonuclease 1. (314 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2383 aa)
WDR82WD repeat domain 82. (313 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
PDE12Phosphodiesterase 12. (608 aa)
EXOSC2Exosome component 2. (293 aa)
SMG6SMG6 nonsense mediated mRNA decay factor. (1413 aa)
NANOS2Nanos C2HC-type zinc finger 2; Belongs to the nanos family. (138 aa)
MAGOHMago homolog, exon junction complex subunit. (146 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
EXOSC9Exosome component 9. (261 aa)
EXOSC7Exosome component 7. (441 aa)
NUDT17Nudix hydrolase 17. (295 aa)
NUDT15Nudix hydrolase 15. (164 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa)
FHITBis(5'-adenosyl)-triphosphatase. (149 aa)
NT5C25'-nucleotidase, cytosolic II. (561 aa)
DNASE1L3Deoxyribonuclease; Belongs to the DNase I family. (311 aa)
DCTPP1dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (170 aa)
UPF3BUPF3B regulator of nonsense mediated mRNA decay. (485 aa)
FITM2Fat storage inducing transmembrane protein 2. (294 aa)
DUTdUTPase domain-containing protein. (225 aa)
ERN2Endoplasmic reticulum to nucleus signaling 2. (927 aa)
ENPP4Ectonucleotide pyrophosphatase/phosphodiesterase 4. (453 aa)
ENTPD3Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (529 aa)
ADA2Adenosine deaminase 2. (563 aa)
AICDAActivation induced cytidine deaminase. (232 aa)
SMG5SMG5 nonsense mediated mRNA decay factor. (1012 aa)
SND1Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. (933 aa)
APEX1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (432 aa)
ENTPD6Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (461 aa)
EXOSC3Exosome component 3. (450 aa)
RIDAReactive intermediate imine deaminase A homolog. (137 aa)
THRAP3Thyroid hormone receptor associated protein 3. (958 aa)
EXOSC5Exosome component 5. (235 aa)
NT5C5', 3'-nucleotidase, cytosolic. (205 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
NBDYNegative regulator of P-body association. (68 aa)
DNASE2BDeoxyribonuclease 2 beta. (361 aa)
SAMD4BSterile alpha motif domain containing 4B. (695 aa)
DPYDDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1026 aa)
EXOSC4Exosome component 4. (245 aa)
ENSFCAP00000035681Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (223 aa)
PDE5APhosphodiesterase. (865 aa)
CNOT9CCR4-NOT transcription complex subunit 9. (299 aa)
ENSFCAP00000036935dUTPase domain-containing protein. (148 aa)
PATL1PAT1 homolog 1, processing body mRNA decay factor. (770 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (540 aa)
PELOProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
SIDT2Transgelin; Belongs to the calponin family. (946 aa)
ENSFCAP00000039364HIT domain-containing protein. (114 aa)
URADOHCU_decarbox domain-containing protein. (174 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
DICER1Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1924 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (1092 aa)
SMG9SMG9 nonsense mediated mRNA decay factor. (520 aa)
ENSFCAP00000040149Uncharacterized protein. (79 aa)
LOC101082293-2Diphosphoinositol polyphosphate phosphohydrolase 3-beta. (164 aa)
ITPAInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. (226 aa)
ENTPD4Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. (632 aa)
MLYCDMalonyl-CoA decarboxylase. (496 aa)
NUDT13Nudix hydrolase 13. (350 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3659 aa)
CDADC1Cytidine and dCMP deaminase domain containing 1. (516 aa)
RNASET2Uncharacterized protein; Belongs to the RNase T2 family. (248 aa)
NUDT19Nudix hydrolase 19. (371 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
NUDT18Nudix hydrolase 18; Belongs to the Nudix hydrolase family. (134 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa)
PARNPoly(A)-specific ribonuclease. (638 aa)
ZFP36L2ZFP36 ring finger protein like 2. (705 aa)
DIS3DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa)
PDE2APhosphodiesterase. (942 aa)
EIF3EEukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (473 aa)
SMG7SMG7 nonsense mediated mRNA decay factor. (1144 aa)
RC3H2Ring finger and CCCH-type domains 2. (1132 aa)
NUDT5Nudix hydrolase 5; Belongs to the Nudix hydrolase family. (228 aa)
EDC3Enhancer of mRNA decapping 3. (543 aa)
NUDT16Nudix hydrolase 16. (195 aa)
ENTPD8Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (501 aa)
ENSFCAP00000047437Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (220 aa)
ZFP36ZFP36 ring finger protein. (513 aa)
RC3H1Ring finger and CCCH-type domains 1. (1133 aa)
XRN15'-3' exoribonuclease 1. (1707 aa)
EXOSC1Exosome component 1. (215 aa)
EXOSC6Exosome component 6. (272 aa)
LIN28BLin-28 homolog B. (258 aa)
NT5M5',3'-nucleotidase, mitochondrial. (235 aa)
PDE9APhosphodiesterase. (542 aa)
ENTPD5FAM161 centrosomal protein B; Belongs to the GDA1/CD39 NTPase family. (1031 aa)
CNOT10CCR4-NOT transcription complex subunit 10. (836 aa)
PDE4CPhosphodiesterase. (732 aa)
ENSFCAP00000051025Uncharacterized protein. (165 aa)
OPRD1YTH N6-methyladenosine RNA binding protein 2. (600 aa)
NUDT1Nudix hydrolase 1. (438 aa)
CNOT6LCCR4-NOT transcription complex subunit 6 like. (694 aa)
SMPDL3ASphingomyelin phosphodiesterase acid like 3A. (506 aa)
THRAThyroid hormone receptor alpha. (733 aa)
EXOSC8Exosome component 8. (298 aa)
DIS3L2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (1028 aa)
RNASEH2CRibonuclease H2 subunit C. (225 aa)
AGO3Argonaute RISC catalytic component 3; Belongs to the argonaute family. (825 aa)
DNASE1L1Deoxyribonuclease 1 like 1. (482 aa)
DERADeoxyribose-phosphate aldolase. (369 aa)
PNRC2Proline rich nuclear receptor coactivator 2. (139 aa)
DFFADNA fragmentation factor subunit alpha. (370 aa)
HELZ2Helicase with zinc finger 2. (2928 aa)
KHSRPKH-type splicing regulatory protein. (727 aa)
DNASE1L2Deoxyribonuclease 1 like 2. (356 aa)
FOXL2Forkhead box L2. (357 aa)
ENTPD7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (641 aa)
DCP1BDecapping mRNA 1B. (639 aa)
ADAAdenosine deaminase. (431 aa)
LRRC27Uncharacterized protein. (550 aa)
UPF1UPF1 RNA helicase and ATPase. (1162 aa)
RNASEH1Ribonuclease H1. (305 aa)
APOBEC3Z3CMP/dCMP-type deaminase domain-containing protein. (319 aa)
PDE4DPhosphodiesterase. (809 aa)
GDAGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (466 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (248 aa)
ENSFCAP00000060005Uncharacterized protein. (80 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (517 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (587 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (1027 aa)
PDE4BPhosphodiesterase. (737 aa)
MGAT1Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase. (399 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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