STRINGSTRING
RFFL RFFL ENSFCAP00000051627 ENSFCAP00000051627 RNF126 RNF126 UBE2E3 UBE2E3 ENSFCAP00000053720 ENSFCAP00000053720 UBE2D1 UBE2D1 SUMO3 SUMO3 RNF187 RNF187 CUL3 CUL3 PRKN PRKN BTRC BTRC RNF8 RNF8 RNF34 RNF34 UBE2E2 UBE2E2 UBE2E1 UBE2E1 RNF115 RNF115 UBE2K UBE2K KBTBD6 KBTBD6 KLHL3 KLHL3 HACE1 HACE1 PELI1 PELI1 ENSFCAP00000026963 ENSFCAP00000026963 SYVN1 SYVN1 UBE3A UBE3A ZNRF2 ZNRF2 TOPORS TOPORS NHLRC4 NHLRC4 TRIM32 TRIM32 UBE2A UBE2A RNF146 RNF146 RNF216 RNF216 UBE3C UBE3C ZNRF1 ZNRF1 UBR5 UBR5 ITCH ITCH AMFR AMFR NMI NMI KBTBD7 KBTBD7 FBXO38 FBXO38 RNF5 RNF5 RNF152 RNF152 UBE2C UBE2C DTX3L DTX3L UBE2T UBE2T BFAR BFAR ENSFCAP00000054944 ENSFCAP00000054944 NEDD4L NEDD4L MARCHF6 MARCHF6 UBE2H UBE2H UBE2G1 UBE2G1 ARIH2 ARIH2 TNFAIP3 TNFAIP3 UBE2B UBE2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RFFLRing finger and FYVE like domain containing E3 ubiquitin protein ligase. (528 aa)
ENSFCAP00000051627Uncharacterized protein. (99 aa)
RNF126Ring finger protein 126. (320 aa)
UBE2E3Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. (241 aa)
ENSFCAP00000053720UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (114 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
SUMO3Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (289 aa)
RNF187Ring finger protein 187. (300 aa)
CUL3Cullin 3; Belongs to the cullin family. (857 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (487 aa)
RNF34Ring finger protein 34. (382 aa)
UBE2E2Ubiquitin conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
UBE2E1UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (402 aa)
RNF115Ring finger protein 115. (305 aa)
UBE2KUbiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
KBTBD6Kelch repeat and BTB domain containing 6. (706 aa)
KLHL3Kelch like family member 3. (601 aa)
HACE1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1. (909 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
ENSFCAP00000026963Uncharacterized protein. (73 aa)
SYVN1Synoviolin 1. (612 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (834 aa)
ZNRF2Zinc and ring finger 2. (243 aa)
TOPORSTOP1 binding arginine/serine rich protein. (1042 aa)
NHLRC4NHL repeat containing 4. (123 aa)
TRIM32Uncharacterized protein. (669 aa)
UBE2AUbiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
RNF146Ring finger protein 146. (356 aa)
RNF216Ring finger protein 216. (921 aa)
UBE3CUbiquitin protein ligase E3C. (1084 aa)
ZNRF1Zinc and ring finger 1. (227 aa)
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2798 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
AMFRAutocrine motility factor receptor. (781 aa)
NMIN-myc and STAT interactor. (309 aa)
KBTBD7Kelch repeat and BTB domain containing 7. (679 aa)
FBXO38F-box protein 38. (1155 aa)
RNF5Ring finger protein 5. (180 aa)
RNF152Ring finger protein 152. (203 aa)
UBE2CUbiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (738 aa)
UBE2TUbiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (189 aa)
BFARBifunctional apoptosis regulator. (450 aa)
ENSFCAP00000054944UBIQUITIN_CONJUGAT_2 domain-containing protein. (61 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (1246 aa)
MARCHF6Membrane associated ring-CH-type finger 6. (910 aa)
UBE2HUbiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. (195 aa)
UBE2G1Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (334 aa)
ARIH2RBR-type E3 ubiquitin transferase. (501 aa)
TNFAIP3TNF alpha induced protein 3. (804 aa)
UBE2BUbiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (274 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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