(38 nodes) Regulation of ornithine decarboxylase (ODC) network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PSMD4	26S proteasome non-ATPase regulatory subunit 4. (377 aa)
	PSMB4	Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
	PSMB10	Proteasome subunit beta. (273 aa)
	PSMC2	26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
	PSMA6	Proteasome subunit alpha type. (246 aa)
	LOC102742178	Proteasome subunit alpha type. (234 aa)
	PSMB2	Proteasome subunit beta. (201 aa)
	USP14	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (494 aa)
	LOC102734657	26S proteasome non-ATPase regulatory subunit 1-like. (279 aa)
	PSMC6	26S protease regulatory subunit 10B. (291 aa)
	PSMD14	26S proteasome non-ATPase regulatory subunit 14. (310 aa)
	SHFM1	26S proteasome complex subunit DSS1. (70 aa)
	PSMC5	26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
	PSMB8	Proteasome subunit beta. (276 aa)
	LOC102733981	26S proteasome non-ATPase regulatory subunit 2-like. (125 aa)
	PSME1	Proteasome activator complex subunit 1 isoform X1. (249 aa)
	PSME2	Proteasome activator complex subunit 2 isoform X1. (239 aa)
	PSMD8	LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 8. (351 aa)
	UBLCP1	Ubiquitin-like domain-containing CTD phosphatase 1. (310 aa)
	PSMD7	26S proteasome non-ATPase regulatory subunit 7-like. (324 aa)
	PSMB6	Proteasome subunit beta. (239 aa)
	PSMA3	Proteasome subunit alpha type. (255 aa)
	PSMD11	26S proteasome non-ATPase regulatory subunit 11. (422 aa)
	PSMA7	Proteasome subunit alpha type. (248 aa)
	ADRM1	Proteasomal ubiquitin receptor ADRM1 isoform X1. (406 aa)
	PSMA8	Proteasome subunit alpha type. (250 aa)
	PSMB5	Proteasome subunit beta type-5. (160 aa)
	LOC102735127	26S protease regulatory subunit 4-like isoform X1; Belongs to the AAA ATPase family. (440 aa)
	PSMA4	Proteasome subunit alpha type. (261 aa)
	PSMD10	26S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
	CSF3	Granulocyte colony-stimulating factor. (195 aa)
	PSMA5	Proteasome subunit alpha type. (235 aa)
	LOC102726381	26S proteasome non-ATPase regulatory subunit 1-like. (574 aa)
	PSMD6	26S proteasome non-ATPase regulatory subunit 6 isoform X1. (389 aa)
	LOC102729219	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (778 aa)
	LOC102732367	Proteasome subunit beta type-1-like. (140 aa)
	LOC102735156	Proteasome subunit beta type-5-like. (119 aa)
	LOC102730851	26S protease regulatory subunit 6A-like. (200 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRM1	CSF3	A0A2U3YLT7	A0A2U3Z1Q3	Proteasomal ubiquitin receptor ADRM1 isoform X1.	Granulocyte colony-stimulating factor.	0.996
ADRM1	LOC102726381	A0A2U3YLT7	A0A2U3Z331	Proteasomal ubiquitin receptor ADRM1 isoform X1.	26S proteasome non-ATPase regulatory subunit 1-like.	0.967
ADRM1	LOC102729219	A0A2U3YLT7	A0A2U3Z6Q4	Proteasomal ubiquitin receptor ADRM1 isoform X1.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.965
ADRM1	LOC102730851	A0A2U3YLT7	A0A2U3Z8X8	Proteasomal ubiquitin receptor ADRM1 isoform X1.	26S protease regulatory subunit 6A-like.	0.993
ADRM1	LOC102732367	A0A2U3YLT7	A0A2U3Z731	Proteasomal ubiquitin receptor ADRM1 isoform X1.	Proteasome subunit beta type-1-like.	0.967
ADRM1	LOC102733981	A0A2U3YLT7	A0A2U3Y3C6	Proteasomal ubiquitin receptor ADRM1 isoform X1.	26S proteasome non-ATPase regulatory subunit 2-like.	0.965
ADRM1	LOC102734657	A0A2U3YLT7	A0A2U3XS75	Proteasomal ubiquitin receptor ADRM1 isoform X1.	26S proteasome non-ATPase regulatory subunit 1-like.	0.967
ADRM1	LOC102735127	A0A2U3YLT7	A0A2U3YX40	Proteasomal ubiquitin receptor ADRM1 isoform X1.	26S protease regulatory subunit 4-like isoform X1; Belongs to the AAA ATPase family.	0.998
ADRM1	LOC102735156	A0A2U3YLT7	A0A2U3Z7I8	Proteasomal ubiquitin receptor ADRM1 isoform X1.	Proteasome subunit beta type-5-like.	0.849
ADRM1	LOC102742178	A0A2U3YLT7	A0A2U3XMG0	Proteasomal ubiquitin receptor ADRM1 isoform X1.	Proteasome subunit alpha type.	0.968
ADRM1	PSMA3	A0A2U3YLT7	A0A2U3YKE9	Proteasomal ubiquitin receptor ADRM1 isoform X1.	Proteasome subunit alpha type.	0.951
ADRM1	PSMA4	A0A2U3YLT7	A0A2U3YXE5	Proteasomal ubiquitin receptor ADRM1 isoform X1.	Proteasome subunit alpha type.	0.968
ADRM1	PSMA5	A0A2U3YLT7	A0A2U3Z213	Proteasomal ubiquitin receptor ADRM1 isoform X1.	Proteasome subunit alpha type.	0.957
ADRM1	PSMA6	A0A2U3YLT7	A0A2U3XLE4	Proteasomal ubiquitin receptor ADRM1 isoform X1.	Proteasome subunit alpha type.	0.952
ADRM1	PSMA7	A0A2U3YLT7	A0A2U3YLS9	Proteasomal ubiquitin receptor ADRM1 isoform X1.	Proteasome subunit alpha type.	0.909
ADRM1	PSMA8	A0A2U3YLT7	A0A2U3YPI2	Proteasomal ubiquitin receptor ADRM1 isoform X1.	Proteasome subunit alpha type.	0.909
ADRM1	PSMB10	A0A2U3YLT7	A0A2U3XF99	Proteasomal ubiquitin receptor ADRM1 isoform X1.	Proteasome subunit beta.	0.952
ADRM1	PSMB2	A0A2U3YLT7	A0A2U3XMR0	Proteasomal ubiquitin receptor ADRM1 isoform X1.	Proteasome subunit beta.	0.969
ADRM1	PSMB4	A0A2U3YLT7	A0A2U3XAT0	Proteasomal ubiquitin receptor ADRM1 isoform X1.	Proteasome subunit beta; Belongs to the peptidase T1B family.	0.964
ADRM1	PSMB5	A0A2U3YLT7	A0A2U3YS54	Proteasomal ubiquitin receptor ADRM1 isoform X1.	Proteasome subunit beta type-5.	0.849