(23 nodes) Autophagy - other network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102743442	Autophagy-related protein 3. (314 aa)
	PIK3C3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (811 aa)
	TTC14	Tetratricopeptide repeat protein 14. (769 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (308 aa)
	GABARAPL1	Gamma-aminobutyric acid receptor-associated protein-like 1 isoform X1. (117 aa)
	ATG4C	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (460 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
	ATG2B	Autophagy-related protein 2 homolog B. (1878 aa)
	ATG12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
	GABARAP	Gamma-aminobutyric acid receptor-associated protein. (117 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (255 aa)
	ATG9A	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (743 aa)
	ATG4D	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (330 aa)
	WIPI1	WD repeat domain phosphoinositide-interacting protein 1 isoform X1. (446 aa)
	ULK2	Serine/threonine-protein kinase ULK2. (1036 aa)
	PIK3R4	Phosphoinositide 3-kinase regulatory subunit 4. (1358 aa)
	ULK3	Serine/threonine-protein kinase ULK3 isoform X1. (382 aa)
	ATG4A	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (398 aa)
	LOC102735948	Autophagy-related protein 13-like. (287 aa)
	LOC102743057	Autophagy-related protein 101. (218 aa)
	LOC102744509	Autophagy protein 5-like. (78 aa)
	LOC102740574	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (400 aa)
	LOC102734169	Gamma-aminobutyric acid receptor-associated protein-like 2-like. (117 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG12	ATG2B	A0A2U3XZP0	A0A2U3XWK7	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 2 homolog B.	0.570
ATG12	ATG4A	A0A2U3XZP0	A0A2U3Z063	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.733
ATG12	ATG4C	A0A2U3XZP0	A0A2U3XNA3	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.653
ATG12	ATG4D	A0A2U3XZP0	A0A2U3YBY7	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.673
ATG12	ATG5	A0A2U3XZP0	A0A2U3Y6R5	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG12	ATG9A	A0A2U3XZP0	A0A2U3Y7P8	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.739
ATG12	GABARAP	A0A2U3XZP0	A0A2U3Y5T4	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Gamma-aminobutyric acid receptor-associated protein.	0.942
ATG12	GABARAPL1	A0A2U3XZP0	A0A2U3XLH6	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Gamma-aminobutyric acid receptor-associated protein-like 1 isoform X1.	0.963
ATG12	LOC102734169	A0A2U3XZP0	A0A2U3Z892	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Gamma-aminobutyric acid receptor-associated protein-like 2-like.	0.957
ATG12	LOC102735948	A0A2U3XZP0	A0A2U3Z6I2	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 13-like.	0.699
ATG12	LOC102740574	A0A2U3XZP0	A0A2U3Z7N7	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.582
ATG12	LOC102743057	A0A2U3XZP0	A0A2U3Z6I5	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 101.	0.672
ATG12	LOC102743442	A0A2U3XZP0	A0A2U3X834	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 3.	0.999
ATG12	LOC102744509	A0A2U3XZP0	A0A2U3Z6M9	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5-like.	0.952
ATG12	MTOR	A0A2U3XZP0	A0A2U3XVT2	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.437
ATG12	PIK3C3	A0A2U3XZP0	A0A2U3XF68	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.832
ATG12	PIK3R4	A0A2U3XZP0	A0A2U3YMF7	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Phosphoinositide 3-kinase regulatory subunit 4.	0.800
ATG12	ULK2	A0A2U3XZP0	A0A2U3YGE0	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Serine/threonine-protein kinase ULK2.	0.982
ATG12	ULK3	A0A2U3XZP0	A0A2U3YTV6	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Serine/threonine-protein kinase ULK3 isoform X1.	0.772
ATG12	WIPI1	A0A2U3XZP0	A0A2U3YDZ9	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	WD repeat domain phosphoinositide-interacting protein 1 isoform X1.	0.933