(24 nodes) Circadian rhythm network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RORB	Nuclear receptor ROR-beta. (459 aa)
	CREB1	Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
	FBXL3	F-box/LRR-repeat protein 3. (428 aa)
	PER1	Period circadian protein homolog 1. (1287 aa)
	PRKAB1	5'-AMP-activated protein kinase subunit beta-1. (270 aa)
	CSNK1D	Casein kinase I isoform delta isoform X2. (399 aa)
	PRKAG2	5'-AMP-activated protein kinase subunit gamma-2-like isoform X2. (327 aa)
	LOC102748583	5'-AMP-activated protein kinase subunit gamma-2-like. (129 aa)
	LOC102749983	F-box/WD repeat-containing protein 11-like. (264 aa)
	ARNTL	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5. (583 aa)
	LOC102729383	Class E basic helix-loop-helix protein 40-like isoform X1. (412 aa)
	NR1D1	Nuclear receptor subfamily 1 group D member 1. (613 aa)
	CSNK1E	Casein kinase I isoform epsilon isoform X2. (359 aa)
	LOC102728272	Neuronal PAS domain-containing protein 2-like. (395 aa)
	LOC102728894	Period circadian protein homolog 3-like. (155 aa)
	CRY2	Cryptochrome-2. (527 aa)
	PRKAG1	5'-AMP-activated protein kinase subunit gamma-1 isoform X1. (298 aa)
	CLOCK	LOW QUALITY PROTEIN: clock circadian regulator. (846 aa)
	RORC	Nuclear receptor ROR-gamma isoform X1. (518 aa)
	BHLHE41	Class E basic helix-loop-helix protein 41. (376 aa)
	RBX1	E3 ubiquitin-protein ligase RBX1 isoform X3. (108 aa)
	SKP1	S-phase kinase-associated protein 1 isoform X1; Belongs to the SKP1 family. (163 aa)
	CRY1	Cryptochrome-1. (587 aa)
	PRKAA1	Non-specific serine/threonine protein kinase. (559 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARNTL	BHLHE41	A0A2U3YPE8	A0A2U3X8Z6	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5.	Class E basic helix-loop-helix protein 41.	0.553
ARNTL	CLOCK	A0A2U3YPE8	A0A2U3Z937	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5.	LOW QUALITY PROTEIN: clock circadian regulator.	0.983
ARNTL	CRY1	A0A2U3YPE8	A0A2U3XIF4	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5.	Cryptochrome-1.	0.997
ARNTL	CRY2	A0A2U3YPE8	A0A2U3Z576	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5.	Cryptochrome-2.	0.997
ARNTL	CSNK1D	A0A2U3YPE8	A0A2U3YA12	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5.	Casein kinase I isoform delta isoform X2.	0.899
ARNTL	CSNK1E	A0A2U3YPE8	A0A2U3YW90	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5.	Casein kinase I isoform epsilon isoform X2.	0.899
ARNTL	FBXL3	A0A2U3YPE8	A0A2U3XWQ9	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5.	F-box/LRR-repeat protein 3.	0.546
ARNTL	LOC102728272	A0A2U3YPE8	A0A2U3YX16	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5.	Neuronal PAS domain-containing protein 2-like.	0.984
ARNTL	LOC102728894	A0A2U3YPE8	A0A2U3Z0Y3	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5.	Period circadian protein homolog 3-like.	0.955
ARNTL	LOC102729383	A0A2U3YPE8	A0A2U3YQR4	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5.	Class E basic helix-loop-helix protein 40-like isoform X1.	0.545
ARNTL	LOC102749983	A0A2U3YPE8	A0A2U3YNR1	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5.	F-box/WD repeat-containing protein 11-like.	0.631
ARNTL	NR1D1	A0A2U3YPE8	A0A2U3YRA0	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5.	Nuclear receptor subfamily 1 group D member 1.	0.657
ARNTL	PER1	A0A2U3YPE8	A0A2U3Y3G6	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5.	Period circadian protein homolog 1.	0.955
ARNTL	RORB	A0A2U3YPE8	A0A2U3XIK1	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5.	Nuclear receptor ROR-beta.	0.539
ARNTL	RORC	A0A2U3YPE8	A0A2U3XAH9	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5.	Nuclear receptor ROR-gamma isoform X1.	0.509
BHLHE41	ARNTL	A0A2U3X8Z6	A0A2U3YPE8	Class E basic helix-loop-helix protein 41.	Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5.	0.553
BHLHE41	CLOCK	A0A2U3X8Z6	A0A2U3Z937	Class E basic helix-loop-helix protein 41.	LOW QUALITY PROTEIN: clock circadian regulator.	0.465
BHLHE41	CRY1	A0A2U3X8Z6	A0A2U3XIF4	Class E basic helix-loop-helix protein 41.	Cryptochrome-1.	0.758
BHLHE41	CRY2	A0A2U3X8Z6	A0A2U3Z576	Class E basic helix-loop-helix protein 41.	Cryptochrome-2.	0.641
BHLHE41	CSNK1D	A0A2U3X8Z6	A0A2U3YA12	Class E basic helix-loop-helix protein 41.	Casein kinase I isoform delta isoform X2.	0.427