STRINGSTRING
FAM89A FAM89A ORC3 ORC3 PSME2 PSME2 PSME1 PSME1 PSMB5 PSMB5 PSMC2 PSMC2 UBE2E1 UBE2E1 PSMA1 PSMA1 KPNA5 KPNA5 ORC6 ORC6 MCM8 MCM8 PSMD10 PSMD10 CDC6 CDC6 MCM9 MCM9 LOC111166275 LOC111166275 KXD1 KXD1 KPNB1 KPNB1 FZR1 FZR1 ORC5 ORC5 PSMD3 PSMD3 PSMB3 PSMB3 MCM4 MCM4 PSMB1 PSMB1 LOC111168449 LOC111168449 LOC111168524 LOC111168524 LOC111168528 LOC111168528 LOC111168549 LOC111168549 LOC111168445 LOC111168445 LOC111168515 LOC111168515 LOC111168525 LOC111168525 LOC111168529 LOC111168529 LOC111166421 LOC111166421 LOC111168516 LOC111168516 LOC111168521 LOC111168521 LOC111168526 LOC111168526 LOC111168530 LOC111168530 LOC111169749 LOC111169749 UBE2C UBE2C PSMD13 PSMD13 PSMB4 PSMB4 LOC111168446 LOC111168446 LOC111168460 LOC111168460 GMNN GMNN LOC111168527 LOC111168527 LOC111168531 LOC111168531 ANAPC15 ANAPC15 LOC111168443 LOC111168443 LOC111168448 LOC111168448 LOC111168536 LOC111168536 LOC111168544 LOC111168544 ORC2 ORC2 MCM2 MCM2 LOC111171120 LOC111171120 LOC111171154 LOC111171154 LOC111169315 LOC111169315 PSMD4 PSMD4 PSMD1 PSMD1 LOC111169736 LOC111169736 LOC111169748 LOC111169748 ORC4 ORC4 LOC111171155 LOC111171155 PSMD14 PSMD14 KPNA1 KPNA1 PSMC6 PSMC6 PSMA6 PSMA6 UBE2D1 UBE2D1 PSMA3 PSMA3 TM4SF19 TM4SF19 ANAPC4 ANAPC4 PSMD6 PSMD6 MCM6 MCM6 PSMC1 PSMC1 PSMB2 PSMB2 CDC16 CDC16 LOC111176743 LOC111176743 LOC111176794 LOC111176794 KPNA6 KPNA6 ANAPC2 ANAPC2 ORC1 ORC1 TM7SF3 TM7SF3 PSMD5 PSMD5 PSMB9 PSMB9 BICRAL BICRAL PSMB7 PSMB7 PSMD7 PSMD7 CDT1 CDT1 PSMA5 PSMA5 LOC111179105 LOC111179105 PSMA4 PSMA4 PSMC4 PSMC4 PSMB8 PSMB8 MCM3 MCM3 ANAPC1 ANAPC1 ANAPC5 ANAPC5 PSMD9 PSMD9 PSMA7 PSMA7 MCM5 MCM5 PSMB6 PSMB6 ANAPC10 ANAPC10 PSMD11 PSMD11 ANAPC7 ANAPC7 RPS27A RPS27A PSMA2 PSMA2 PSMF1 PSMF1 ANAPC16 ANAPC16 PSMD12 PSMD12 PSMC3 PSMC3 CDC27 CDC27 LOC111184525 LOC111184525 CDC23 CDC23 FAM89B FAM89B MCM7 MCM7 PSMC5 PSMC5 ANAPC11 ANAPC11 PSMD8 PSMD8 PSMB10 PSMB10 UBE2S UBE2S
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FAM89AProtein FAM89A. (178 aa)
ORC3Origin recognition complex subunit 3 isoform X1. (713 aa)
PSME2Proteasome activator complex subunit 2. (239 aa)
PSME1Proteasome activator complex subunit 1. (249 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
UBE2E1Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
KPNA5Importin subunit alpha; Functions in nuclear protein import. (536 aa)
ORC6Origin recognition complex subunit 6. (273 aa)
MCM8DNA helicase MCM8; Belongs to the MCM family. (832 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (647 aa)
MCM9DNA helicase MCM9 isoform X1; Belongs to the MCM family. (1144 aa)
LOC111166275Proteasome activator complex subunit 3-like. (165 aa)
KXD1kxDL motif-containing protein 1 isoform X1. (196 aa)
KPNB1Importin subunit beta-1. (876 aa)
FZR1Fizzy-related protein homolog isoform X1. (496 aa)
ORC5Origin recognition complex subunit 5. (435 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
PSMB3Proteasome subunit beta. (205 aa)
MCM4DNA helicase; Belongs to the MCM family. (836 aa)
PSMB1Proteasome subunit beta. (241 aa)
LOC111168449Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168524Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168528Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168549Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC111168445Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168515Histone H3; Belongs to the histone H3 family. (136 aa)
LOC111168525Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168529Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111166421Proteasome activator complex subunit 3. (254 aa)
LOC111168516Histone H3; Belongs to the histone H3 family. (136 aa)
LOC111168521Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC111168526Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168530Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111169749Histone H2B; Belongs to the histone H2B family. (126 aa)
UBE2CUbiquitin-conjugating enzyme E2 C isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (203 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
LOC111168446Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168460Histone H2B; Belongs to the histone H2B family. (127 aa)
GMNNGeminin. (210 aa)
LOC111168527Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168531Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (112 aa)
ANAPC15Anaphase-promoting complex subunit 15 isoform X1. (125 aa)
LOC111168443Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC111168448Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168536Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC111168544Histone H2B type 1-L-like; Belongs to the histone H2B family. (143 aa)
ORC2Origin recognition complex subunit 2. (578 aa)
MCM2DNA helicase; Belongs to the MCM family. (903 aa)
LOC111171120Late histone H2B.L4-like; Belongs to the histone H2B family. (135 aa)
LOC111171154Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC111169315Histone H2B; Belongs to the histone H2B family. (126 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform X1. (380 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (954 aa)
LOC111169736Histone H2B; Belongs to the histone H2B family. (197 aa)
LOC111169748Histone H2A; Belongs to the histone H2A family. (129 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
LOC111171155Histone H2B; Belongs to the histone H2B family. (126 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14 isoform X1. (310 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (538 aa)
PSMC626S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (190 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
TM4SF19Transmembrane 4 L6 family member 19. (202 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6 isoform X1. (452 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
PSMC126S proteasome regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa)
PSMB2Proteasome subunit beta. (201 aa)
CDC16Cell division cycle protein 16 homolog isoform X1. (620 aa)
LOC111176743Histone H2B; Belongs to the histone H2B family. (122 aa)
LOC111176794Histone H2A; Belongs to the histone H2A family. (129 aa)
KPNA6Importin subunit alpha; Functions in nuclear protein import. (577 aa)
ANAPC2Anaphase-promoting complex subunit 2; Belongs to the cullin family. (820 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (863 aa)
TM7SF3Transmembrane 7 superfamily member 3. (570 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (504 aa)
PSMB9Proteasome subunit beta. (219 aa)
BICRALBRD4-interacting chromatin-remodeling complex-associated protein-like. (1079 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (322 aa)
CDT1DNA replication factor Cdt1. (551 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
LOC111179105Histone H2A; Belongs to the histone H2A family. (128 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
PSMB8Proteasome subunit beta. (276 aa)
MCM3DNA helicase; Belongs to the MCM family. (808 aa)
ANAPC1Anaphase-promoting complex subunit 1 isoform X1. (1944 aa)
ANAPC5Anaphase-promoting complex subunit 5 isoform X1. (755 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
PSMB6Proteasome subunit beta. (239 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (422 aa)
ANAPC7LOW QUALITY PROTEIN: anaphase-promoting complex subunit 7. (534 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMF1Proteasome inhibitor PI31 subunit isoform X1. (270 aa)
ANAPC16Anaphase-promoting complex subunit 16. (109 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (456 aa)
PSMC326S proteasome regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (423 aa)
CDC27Cell division cycle protein 27 homolog isoform X1. (837 aa)
LOC111184525Histone H2A; Belongs to the histone H2A family. (128 aa)
CDC23Cell division cycle protein 23 homolog. (597 aa)
FAM89BProtein FAM89B. (192 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
PSMC526S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
ANAPC11Anaphase-promoting complex subunit 11. (84 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (351 aa)
PSMB10Proteasome subunit beta. (273 aa)
UBE2SUbiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (223 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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