STRINGSTRING
CCDC155 CCDC155 MLH1 MLH1 TERF2 TERF2 TERB2 TERB2 MAJIN MAJIN ATM ATM TERB1 TERB1 SPO11 SPO11 SUN1 SUN1 TERF1 TERF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCDC155Coiled-coil domain containing 155. (581 aa)
MLH1MutL homolog 1. (759 aa)
TERF2TERF2_RBM domain-containing protein. (142 aa)
TERB2Telomere repeat binding bouquet formation protein 2. (220 aa)
MAJINMembrane anchored junction protein. (258 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3055 aa)
TERB1Telomere repeat binding bouquet formation protein 1. (770 aa)
SPO11SPO11 initiator of meiotic double stranded breaks. (396 aa)
SUN1Sad1 and UNC84 domain containing 1. (766 aa)
TERF1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (437 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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