STRINGSTRING
YLPM1 YLPM1 RBM15B RBM15B RBM15 RBM15 NPAT NPAT SCNM1 SCNM1 HIF1A HIF1A PIP5K1A PIP5K1A NSRP1 NSRP1 MEF2C MEF2C ANGEL2 ANGEL2 HIPK3 HIPK3 DDX39B DDX39B NOLC1 NOLC1 SMNDC1 SMNDC1 ZBTB16 ZBTB16 POLDIP3 POLDIP3 SARNP SARNP DHX36 DHX36 RPA1 RPA1 ALKBH5 ALKBH5 CREBBP CREBBP FTO FTO ZC3H18 ZC3H18 EWSR1 EWSR1 SRSF11 SRSF11 TCIM TCIM SON SON GEMIN7 GEMIN7 KLHL20 KLHL20 CALCOCO2 CALCOCO2 G3THJ7_LOXAF G3THJ7_LOXAF TRIM16 TRIM16 FYTTD1 FYTTD1 TOE1 TOE1 COIL COIL ICE2 ICE2 N4BP1 N4BP1 G3TJM4_LOXAF G3TJM4_LOXAF SRSF3 SRSF3 HABP4 HABP4 GLIS2 GLIS2 RBM23 RBM23 G3TLG2_LOXAF G3TLG2_LOXAF HSF1 HSF1 DDX39A DDX39A PHAX PHAX IKBKE IKBKE SUMO1 SUMO1 NCOR2 NCOR2 RBM14 RBM14 APEX1 APEX1 YTHDC1 YTHDC1 TP53INP2 TP53INP2 G3TRH4_LOXAF G3TRH4_LOXAF TRIM8 TRIM8 G3TRR6_LOXAF G3TRR6_LOXAF RNF111 RNF111 ZC3H8 ZC3H8 PRPF31 PRPF31 DDX5 DDX5 SRPK2 SRPK2 CIITA CIITA DGKQ DGKQ CHEK2 CHEK2 OIP5 OIP5 SETBP1 SETBP1 G3SSC9_LOXAF G3SSC9_LOXAF TUT1 TUT1 ZC3H14 ZC3H14 PML PML TDP2 TDP2 CSNK1A1 CSNK1A1 DDX1 DDX1 G3SPK1_LOXAF G3SPK1_LOXAF NOC3L NOC3L LSG1 LSG1 G3TS21_LOXAF G3TS21_LOXAF ZMYM2 ZMYM2 SDCBP2 SDCBP2 G3TU55_LOXAF G3TU55_LOXAF HSPB3 HSPB3 ZNF830 ZNF830 RBM4 RBM4 LRCH4 LRCH4 HINFP HINFP FAM76B FAM76B GEMIN6 GEMIN6 DAXX DAXX ELL ELL RBM27 RBM27 G3U0G5_LOXAF G3U0G5_LOXAF RDM1 RDM1 RNF4 RNF4 MORC3 MORC3 AKAP17A AKAP17A WT1 WT1 HIPK2 HIPK2 WBP11 WBP11 G3U4L1_LOXAF G3U4L1_LOXAF G3U4W9_LOXAF G3U4W9_LOXAF RNF6 RNF6 G3U612_LOXAF G3U612_LOXAF G3U6D1_LOXAF G3U6D1_LOXAF G3U6U6_LOXAF G3U6U6_LOXAF SRSF10 SRSF10 FASTK FASTK SRSF6 SRSF6 G3U994_LOXAF G3U994_LOXAF FAM118A FAM118A G3UAE1_LOXAF G3UAE1_LOXAF G3UAZ0_LOXAF G3UAZ0_LOXAF G3UC69_LOXAF G3UC69_LOXAF G3UCI8_LOXAF G3UCI8_LOXAF G3UDE4_LOXAF G3UDE4_LOXAF MLIP MLIP DUSP11 DUSP11 H1-0 H1-0 TP53INP1 TP53INP1 RBM25 RBM25 DYRK1A DYRK1A NRDE2 NRDE2 SRRM2 SRRM2 CHFR CHFR SRPK1 SRPK1 NR3C1 NR3C1 SRSF5 SRSF5 PTEN PTEN SUMO2 SUMO2 G3UE49_LOXAF G3UE49_LOXAF SRSF4 SRSF4 RBM39 RBM39 G3UHE5_LOXAF G3UHE5_LOXAF AK6 AK6 G3UHY3_LOXAF G3UHY3_LOXAF G3UI57_LOXAF G3UI57_LOXAF G3UIR7_LOXAF G3UIR7_LOXAF G3UJ00_LOXAF G3UJ00_LOXAF G3UJ15_LOXAF G3UJ15_LOXAF SRSF1 SRSF1 G3UK14_LOXAF G3UK14_LOXAF WBP4 WBP4 TRIM69 TRIM69 RAD54L2 RAD54L2 HOXA6 HOXA6 SRPK3 SRPK3 RBM11 RBM11 WTAP WTAP SRSF2 SRSF2 TP53 TP53 WRAP53 WRAP53 USPL1 USPL1 AIRE AIRE DZIP1 DZIP1 DDX17 DDX17 G3UN99_LOXAF G3UN99_LOXAF PNISR PNISR CPSF6 CPSF6 G3ULT4_LOXAF G3ULT4_LOXAF BLM BLM THRAP3 THRAP3 CDC40 CDC40 RPAIN RPAIN FAM118B FAM118B MAPK7 MAPK7 ZPR1 ZPR1 DDX46 DDX46 ANKRD2 ANKRD2 FRG1 FRG1 BCL6 BCL6 EPAS1 EPAS1 CASP8AP2 CASP8AP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
YLPM1YLP motif containing 1. (1949 aa)
RBM15BRNA binding motif protein 15B. (563 aa)
RBM15RNA binding motif protein 15. (959 aa)
NPATNuclear protein, coactivator of histone transcription. (1032 aa)
SCNM1Sodium channel modifier 1. (229 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (836 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (528 aa)
NSRP1Nuclear speckle splicing regulatory protein 1. (446 aa)
MEF2CMyocyte enhancer factor 2C. (473 aa)
ANGEL2Angel homolog 2. (547 aa)
HIPK3Homeodomain interacting protein kinase 3. (1214 aa)
DDX39BDExD-box helicase 39B. (427 aa)
NOLC1Nucleolar and coiled-body phosphoprotein 1. (694 aa)
SMNDC1Survival motor neuron domain containing 1. (238 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
POLDIP3DNA polymerase delta interacting protein 3. (430 aa)
SARNPSAP domain containing ribonucleoprotein. (210 aa)
DHX36DEAH-box helicase 36. (1001 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (643 aa)
ALKBH5AlkB homolog 5, RNA demethylase. (394 aa)
CREBBPCREB binding protein. (2433 aa)
FTOFTO alpha-ketoglutarate dependent dioxygenase. (505 aa)
ZC3H18Zinc finger CCCH-type containing 18. (981 aa)
EWSR1EWS RNA binding protein 1. (663 aa)
SRSF11Serine and arginine rich splicing factor 11. (475 aa)
TCIMTranscriptional and immune response regulator. (106 aa)
SONSON DNA binding protein. (2352 aa)
GEMIN7Gem nuclear organelle associated protein 7. (131 aa)
KLHL20Kelch like family member 20. (627 aa)
CALCOCO2Calcium binding and coiled-coil domain 2. (450 aa)
G3THJ7_LOXAFUncharacterized protein. (649 aa)
TRIM16Uncharacterized protein. (549 aa)
FYTTD1Forty-two-three domain containing 1. (317 aa)
TOE1Target of EGR1, exonuclease. (510 aa)
COILCoilin. (577 aa)
ICE2Interactor of little elongation complex ELL subunit 2. (976 aa)
N4BP1NEDD4 binding protein 1. (825 aa)
G3TJM4_LOXAFUncharacterized protein. (228 aa)
SRSF3Serine and arginine rich splicing factor 3. (164 aa)
HABP4Hyaluronan binding protein 4. (411 aa)
GLIS2GLIS family zinc finger 2. (520 aa)
RBM23RNA binding motif protein 23. (447 aa)
G3TLG2_LOXAFRRM domain-containing protein. (437 aa)
HSF1Heat shock transcription factor 1. (503 aa)
DDX39ADExD-box helicase 39A. (427 aa)
PHAXPhosphorylated adaptor for RNA export. (393 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (722 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
NCOR2Nuclear receptor corepressor 2. (2467 aa)
RBM14RNA binding motif protein 14. (554 aa)
APEX1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa)
YTHDC1YTH domain containing 1. (730 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (221 aa)
G3TRH4_LOXAFUncharacterized protein. (449 aa)
TRIM8Tripartite motif containing 8. (461 aa)
G3TRR6_LOXAFUncharacterized protein. (486 aa)
RNF111Ring finger protein 111. (992 aa)
ZC3H8Zinc finger CCCH-type containing 8. (303 aa)
PRPF31Pre-mRNA processing factor 31. (499 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (648 aa)
SRPK2SRSF protein kinase 2. (674 aa)
CIITAClass II major histocompatibility complex transactivator. (1150 aa)
DGKQDiacylglycerol kinase. (850 aa)
CHEK2Checkpoint kinase 2. (550 aa)
OIP5Opa interacting protein 5. (230 aa)
SETBP1SET binding protein 1. (1280 aa)
G3SSC9_LOXAFTudor domain-containing protein. (304 aa)
TUT1RRM domain-containing protein. (869 aa)
ZC3H14Zinc finger CCCH-type containing 14. (739 aa)
PMLPromyelocytic leukemia. (861 aa)
TDP2Tyrosyl-DNA phosphodiesterase 2. (352 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (337 aa)
DDX1DEAD-box helicase 1. (740 aa)
G3SPK1_LOXAFSmall ubiquitin-related modifier. (87 aa)
NOC3LNucleolar complex protein 3 homolog. (802 aa)
LSG1Large 60S subunit nuclear export GTPase 1. (657 aa)
G3TS21_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (363 aa)
ZMYM2Zinc finger MYM-type containing 2. (1377 aa)
SDCBP2Syndecan binding protein 2. (294 aa)
G3TU55_LOXAFRRM domain-containing protein. (487 aa)
HSPB3Heat shock protein family B (small) member 3; Belongs to the small heat shock protein (HSP20) family. (150 aa)
ZNF830Zinc finger protein 830. (346 aa)
RBM4RNA binding motif protein 4. (365 aa)
LRCH4Leucine rich repeats and calponin homology domain containing 4. (678 aa)
HINFPHistone H4 transcription factor. (504 aa)
FAM76BFamily with sequence similarity 76 member B. (340 aa)
GEMIN6Gem nuclear organelle associated protein 6. (167 aa)
DAXXDeath domain associated protein. (689 aa)
ELLElongation factor for RNA polymerase II. (552 aa)
RBM27Uncharacterized protein. (1065 aa)
G3U0G5_LOXAFCwf21 domain-containing protein. (658 aa)
RDM1RAD52 motif containing 1. (284 aa)
RNF4Ring finger protein 4. (194 aa)
MORC3MORC family CW-type zinc finger 3. (948 aa)
AKAP17AA-kinase anchoring protein 17A. (429 aa)
WT1WT1 transcription factor. (450 aa)
HIPK2Homeodomain interacting protein kinase 2. (1207 aa)
WBP11Uncharacterized protein. (648 aa)
G3U4L1_LOXAFRING-type domain-containing protein. (192 aa)
G3U4W9_LOXAFUncharacterized protein. (143 aa)
RNF6Ring finger protein 6. (683 aa)
G3U612_LOXAFAlbA_2 domain-containing protein. (303 aa)
G3U6D1_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (364 aa)
G3U6U6_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (367 aa)
SRSF10Serine and arginine rich splicing factor 10. (264 aa)
FASTKFas activated serine/threonine kinase. (549 aa)
SRSF6Serine and arginine rich splicing factor 6. (261 aa)
G3U994_LOXAFSmall ubiquitin-related modifier. (95 aa)
FAM118AFamily with sequence similarity 118 member A. (357 aa)
G3UAE1_LOXAFUncharacterized protein. (224 aa)
G3UAZ0_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (364 aa)
G3UC69_LOXAFRRM domain-containing protein. (163 aa)
G3UCI8_LOXAFUncharacterized protein. (301 aa)
G3UDE4_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (362 aa)
MLIPMuscular LMNA interacting protein. (795 aa)
DUSP11Dual specificity phosphatase 11. (334 aa)
H1-0H1 histone family member 0. (194 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (241 aa)
RBM25PWI domain-containing protein. (636 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (760 aa)
NRDE2NRDE-2, necessary for RNA interference, domain containing. (1137 aa)
SRRM2Serine/arginine repetitive matrix 2. (2641 aa)
CHFRCheckpoint with forkhead and ring finger domains. (660 aa)
SRPK1SRSF protein kinase 1. (649 aa)
NR3C1Nuclear receptor subfamily 3 group C member 1. (776 aa)
SRSF5Serine and arginine rich splicing factor 5. (271 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
G3UE49_LOXAFSmall ubiquitin-related modifier. (95 aa)
SRSF4Serine and arginine rich splicing factor 4. (505 aa)
RBM39RNA binding motif protein 39. (530 aa)
G3UHE5_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (367 aa)
AK6Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (172 aa)
G3UHY3_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (288 aa)
G3UI57_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (360 aa)
G3UIR7_LOXAFUncharacterized protein. (401 aa)
G3UJ00_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (360 aa)
G3UJ15_LOXAFETS domain-containing protein. (442 aa)
SRSF1Uncharacterized protein. (248 aa)
G3UK14_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (365 aa)
WBP4WW domain binding protein 4. (369 aa)
TRIM69Tripartite motif containing 69. (332 aa)
RAD54L2RAD54 like 2. (1467 aa)
HOXA6Homeobox A6. (233 aa)
SRPK3SRSF protein kinase 3. (565 aa)
RBM11RNA binding motif protein 11. (238 aa)
WTAPWT1 associated protein. (396 aa)
SRSF2RRM domain-containing protein. (211 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (392 aa)
WRAP53WD repeat containing antisense to TP53. (538 aa)
USPL1Ubiquitin specific peptidase like 1. (1088 aa)
AIREAutoimmune regulator. (557 aa)
DZIP1DAZ interacting zinc finger protein 1. (861 aa)
DDX17Uncharacterized protein; Belongs to the DEAD box helicase family. (541 aa)
G3UN99_LOXAFSmall ubiquitin-related modifier. (100 aa)
PNISRPNN interacting serine and arginine rich protein. (813 aa)
CPSF6Cleavage and polyadenylation specific factor 6. (553 aa)
G3ULT4_LOXAFCellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (367 aa)
BLMUncharacterized protein. (528 aa)
THRAP3Thyroid hormone receptor associated protein 3. (955 aa)
CDC40Cell division cycle 40. (581 aa)
RPAINRPA interacting protein. (219 aa)
FAM118BFamily with sequence similarity 118 member B. (351 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (801 aa)
ZPR1ZPR1 zinc finger. (463 aa)
DDX46DEAD-box helicase 46. (1033 aa)
ANKRD2Ankyrin repeat domain 2. (332 aa)
FRG1FSHD region gene 1. (258 aa)
BCL6BCL6 transcription repressor. (708 aa)
EPAS1Endothelial PAS domain protein 1. (861 aa)
CASP8AP2Caspase 8 associated protein 2. (1974 aa)
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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