(7 nodes) (2018) Intracellular redistribution of neuronal peroxisomes in response to ACBD5 expression. network (Equus caballus)

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Your Input:
	VAPB	VAMP associated protein B and C. (284 aa)
	POMC	Melanotropin beta; MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes; Belongs to the POMC family. (332 aa)
	GFAP	Glial fibrillary acidic protein; Belongs to the intermediate filament family. (559 aa)
	PEX5	Peroxisomal biogenesis factor 5. (661 aa)
	ACBD5	Acyl-CoA-binding domain-containing protein 5; Binds medium- and long-chain acyl-CoA esters. (532 aa)
	SPAST	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (616 aa)
	VAPA	VAMP associated protein A. (317 aa)

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACBD5	PEX5	ENSECAP00000049407	ENSECAP00000014984	Acyl-CoA-binding domain-containing protein 5; Binds medium- and long-chain acyl-CoA esters.	Peroxisomal biogenesis factor 5.	0.621
ACBD5	VAPA	ENSECAP00000049407	ENSECAP00000029600	Acyl-CoA-binding domain-containing protein 5; Binds medium- and long-chain acyl-CoA esters.	VAMP associated protein A.	0.693
ACBD5	VAPB	ENSECAP00000049407	ENSECAP00000011107	Acyl-CoA-binding domain-containing protein 5; Binds medium- and long-chain acyl-CoA esters.	VAMP associated protein B and C.	0.669
GFAP	POMC	ENSECAP00000008384	ENSECAP00000013923	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Melanotropin beta; MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes; Belongs to the POMC family.	0.620
PEX5	ACBD5	ENSECAP00000014984	ENSECAP00000049407	Peroxisomal biogenesis factor 5.	Acyl-CoA-binding domain-containing protein 5; Binds medium- and long-chain acyl-CoA esters.	0.621
PEX5	SPAST	ENSECAP00000014984	ENSECAP00000031923	Peroxisomal biogenesis factor 5.	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...]	0.481
POMC	GFAP	ENSECAP00000013923	ENSECAP00000008384	Melanotropin beta; MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes; Belongs to the POMC family.	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	0.620
SPAST	PEX5	ENSECAP00000031923	ENSECAP00000014984	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...]	Peroxisomal biogenesis factor 5.	0.481
SPAST	VAPA	ENSECAP00000031923	ENSECAP00000029600	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...]	VAMP associated protein A.	0.444
SPAST	VAPB	ENSECAP00000031923	ENSECAP00000011107	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...]	VAMP associated protein B and C.	0.546
VAPA	ACBD5	ENSECAP00000029600	ENSECAP00000049407	VAMP associated protein A.	Acyl-CoA-binding domain-containing protein 5; Binds medium- and long-chain acyl-CoA esters.	0.693
VAPA	SPAST	ENSECAP00000029600	ENSECAP00000031923	VAMP associated protein A.	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...]	0.444
VAPA	VAPB	ENSECAP00000029600	ENSECAP00000011107	VAMP associated protein A.	VAMP associated protein B and C.	0.763
VAPB	ACBD5	ENSECAP00000011107	ENSECAP00000049407	VAMP associated protein B and C.	Acyl-CoA-binding domain-containing protein 5; Binds medium- and long-chain acyl-CoA esters.	0.669
VAPB	SPAST	ENSECAP00000011107	ENSECAP00000031923	VAMP associated protein B and C.	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...]	0.546
VAPB	VAPA	ENSECAP00000011107	ENSECAP00000029600	VAMP associated protein B and C.	VAMP associated protein A.	0.763