STRINGSTRING
NTN4 NTN4 NTN5 NTN5 SLIT2 SLIT2 SLIT1 SLIT1 DSCAM DSCAM UNC5A UNC5A RGMB RGMB ROBO3 ROBO3 ROBO4 ROBO4 SLIT3 SLIT3 ROBO2 ROBO2 UNC5B UNC5B UNC5C UNC5C NEO1 NEO1 NELL2 NELL2 DCC DCC RGMA RGMA NTN1 NTN1 ROBO1 ROBO1 DSCAML1 DSCAML1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NTN4Netrin 4. (628 aa)
NTN5Netrin-5. (499 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
DSCAMDS cell adhesion molecule. (2008 aa)
UNC5ANetrin receptor UNC5A isoform X3. (902 aa)
RGMBRepulsive guidance molecule BMP co-receptor b. (480 aa)
ROBO3Roundabout guidance receptor 3. (1387 aa)
ROBO4Roundabout guidance receptor 4. (1010 aa)
SLIT3Slit guidance ligand 3. (1523 aa)
ROBO2Roundabout homolog 2 isoform X5. (1439 aa)
UNC5BUnc-5 netrin receptor B. (934 aa)
UNC5CUnc-5 netrin receptor C. (937 aa)
NEO1Neogenin 1. (1465 aa)
NELL2Neural EGFL like 2. (826 aa)
DCCDCC netrin 1 receptor. (1423 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (456 aa)
NTN1Netrin-1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (By similarity). Involved in dorsal root ganglion axon projection towards the spinal cord (By similarity). It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involve [...] (651 aa)
ROBO1Roundabout guidance receptor 1. (1687 aa)
DSCAML1DS cell adhesion molecule like 1. (2111 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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