(22 nodes) Mixed, incl. Glycolipid catabolic process, and Beta-galactosidase 1-like network (Sus scrofa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NEU1	Sialidase-1; Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage (By similarity). (432 aa)
	MANBA	Mannosidase beta. (877 aa)
	HEXB	Beta-hexosaminidase subunit beta; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. (538 aa)
	CHIT1	Chitinase 1; Belongs to the glycosyl hydrolase 18 family. (466 aa)
	GLB1L	Galactosidase beta 1 like; Belongs to the glycosyl hydrolase 35 family. (651 aa)
	NEU2	Neuraminidase 2. (379 aa)
	GALC	Galactocerebrosidase isoform a. (685 aa)
	GLB1	Beta-galactosidase. (614 aa)
	CHIA	Chitin-binding type-2 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (478 aa)
	FUCA1	Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (467 aa)
	LOC110255463	Glyco_hydro_35 domain-containing protein; Belongs to the glycosyl hydrolase 35 family. (636 aa)
	HEXA	Beta-hexosaminidase. (545 aa)
	GBGT1	Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group). (397 aa)
	NEU4	Neuraminidase 4. (471 aa)
	NAGA	Alpha-galactosidase. (406 aa)
	GLA	Alpha-galactosidase. (433 aa)
	NAGK	N-acetylglucosamine kinase. (402 aa)
	UGT8	UDP glycosyltransferase 8; Belongs to the UDP-glycosyltransferase family. (556 aa)
	GAL3ST1	Galactose-3-O-sulfotransferase 1. (423 aa)
	ARSA	Sulfatase domain-containing protein. (519 aa)
	CTSA	Carboxypeptidase; Belongs to the peptidase S10 family. (485 aa)
	FUCA2	Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (461 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARSA	GALC	ENSSSCP00000069615	ENSSSCP00000021318	Sulfatase domain-containing protein.	Galactocerebrosidase isoform a.	0.948
ARSA	GLA	ENSSSCP00000069615	ENSSSCP00000051974	Sulfatase domain-containing protein.	Alpha-galactosidase.	0.939
ARSA	NEU1	ENSSSCP00000069615	ENSSSCP00000001513	Sulfatase domain-containing protein.	Sialidase-1; Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage (By similarity).	0.949
ARSA	NEU2	ENSSSCP00000069615	ENSSSCP00000017266	Sulfatase domain-containing protein.	Neuraminidase 2.	0.900
ARSA	NEU4	ENSSSCP00000069615	ENSSSCP00000045378	Sulfatase domain-containing protein.	Neuraminidase 4.	0.910
ARSA	UGT8	ENSSSCP00000069615	ENSSSCP00000058338	Sulfatase domain-containing protein.	UDP glycosyltransferase 8; Belongs to the UDP-glycosyltransferase family.	0.948
CHIA	CHIT1	ENSSSCP00000024798	ENSSSCP00000016409	Chitin-binding type-2 domain-containing protein; Belongs to the glycosyl hydrolase 18 family.	Chitinase 1; Belongs to the glycosyl hydrolase 18 family.	0.902
CHIA	HEXA	ENSSSCP00000024798	ENSSSCP00000039891	Chitin-binding type-2 domain-containing protein; Belongs to the glycosyl hydrolase 18 family.	Beta-hexosaminidase.	0.931
CHIA	HEXB	ENSSSCP00000024798	ENSSSCP00000014965	Chitin-binding type-2 domain-containing protein; Belongs to the glycosyl hydrolase 18 family.	Beta-hexosaminidase subunit beta; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.	0.931
CHIA	NAGK	ENSSSCP00000024798	ENSSSCP00000052135	Chitin-binding type-2 domain-containing protein; Belongs to the glycosyl hydrolase 18 family.	N-acetylglucosamine kinase.	0.900
CHIT1	CHIA	ENSSSCP00000016409	ENSSSCP00000024798	Chitinase 1; Belongs to the glycosyl hydrolase 18 family.	Chitin-binding type-2 domain-containing protein; Belongs to the glycosyl hydrolase 18 family.	0.902
CHIT1	HEXA	ENSSSCP00000016409	ENSSSCP00000039891	Chitinase 1; Belongs to the glycosyl hydrolase 18 family.	Beta-hexosaminidase.	0.931
CHIT1	HEXB	ENSSSCP00000016409	ENSSSCP00000014965	Chitinase 1; Belongs to the glycosyl hydrolase 18 family.	Beta-hexosaminidase subunit beta; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.	0.931
CHIT1	NAGK	ENSSSCP00000016409	ENSSSCP00000052135	Chitinase 1; Belongs to the glycosyl hydrolase 18 family.	N-acetylglucosamine kinase.	0.900
CTSA	FUCA2	ENSSSCP00000071302	ENSSSCP00000071494	Carboxypeptidase; Belongs to the peptidase S10 family.	Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.	0.446
CTSA	GLB1	ENSSSCP00000071302	ENSSSCP00000023183	Carboxypeptidase; Belongs to the peptidase S10 family.	Beta-galactosidase.	0.918
CTSA	GLB1L	ENSSSCP00000071302	ENSSSCP00000017176	Carboxypeptidase; Belongs to the peptidase S10 family.	Galactosidase beta 1 like; Belongs to the glycosyl hydrolase 35 family.	0.725
CTSA	LOC110255463	ENSSSCP00000071302	ENSSSCP00000028225	Carboxypeptidase; Belongs to the peptidase S10 family.	Glyco_hydro_35 domain-containing protein; Belongs to the glycosyl hydrolase 35 family.	0.407
CTSA	NEU1	ENSSSCP00000071302	ENSSSCP00000001513	Carboxypeptidase; Belongs to the peptidase S10 family.	Sialidase-1; Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage (By similarity).	0.930
CTSA	NEU2	ENSSSCP00000071302	ENSSSCP00000017266	Carboxypeptidase; Belongs to the peptidase S10 family.	Neuraminidase 2.	0.639