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A0A287A6V0_PIG A0A287A6V0_PIG CYP2U1 CYP2U1 CYP1A2 CYP1A2 LOC110256857 LOC110256857 CYP7A1 CYP7A1 CYP1A1 CYP1A1 CYP2A19 CYP2A19 CYP2F1 CYP2F1 CYP2B22 CYP2B22 CYP2W1 CYP2W1 CYP2C33 CYP2C33 LOC100737508 LOC100737508 CYP2E1 CYP2E1 A0A286ZQC2_PIG A0A286ZQC2_PIG CYP2J34 CYP2J34 CYP3A22 CYP3A22 CYP2R1 CYP2R1 CYP2D25 CYP2D25 CYP2S1 CYP2S1 TTI2 TTI2 HMOX1 HMOX1 COQ6 COQ6 CYP2C36 CYP2C36 CYP1B1 CYP1B1 HMOX2 HMOX2 CYP19A1 CYP19A1 A0A287ARF8_PIG A0A287ARF8_PIG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A287A6V0_PIGUncharacterized protein. (155 aa)
CYP2U1Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (543 aa)
CYP1A2Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (516 aa)
LOC110256857Uncharacterized protein. (162 aa)
CYP7A1Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...] (554 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (538 aa)
CYP2A19Cytochorme P450 2A19; Belongs to the cytochrome P450 family. (494 aa)
CYP2F1Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. (492 aa)
CYP2B22Uncharacterized protein; Belongs to the cytochrome P450 family. (529 aa)
CYP2W1Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family. (469 aa)
CYP2C33Cytochrome P450 2C8 isoform a; Belongs to the cytochrome P450 family. (494 aa)
LOC100737508Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
CYP2E1Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. (499 aa)
A0A286ZQC2_PIGUncharacterized protein. (502 aa)
CYP2J34Uncharacterized protein; Belongs to the cytochrome P450 family. (554 aa)
CYP3A22Cytochrome P450 3A29; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (667 aa)
CYP2R1Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (500 aa)
CYP2D25Vitamin D(3) 25-hydroxylase; Catalyzes the first step in the metabolic activation of vitamin D(3) into 1-alpha,25-dihydroxyvitamin D(3), its active, hormonal form. (500 aa)
CYP2S1Cytochrome P450 family 2 subfamily S member 1; Belongs to the cytochrome P450 family. (650 aa)
TTI2TELO2 interacting protein 2. (507 aa)
HMOX1Heme oxygenase 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. (287 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (481 aa)
CYP2C36Cytochrome P450 2C42; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (843 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
HMOX2Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (316 aa)
CYP19A1Aromatase 3; Catalyzes the formation of aromatic C18 estrogens from C19 androgens; Belongs to the cytochrome P450 family. (551 aa)
A0A287ARF8_PIGUncharacterized protein. (161 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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