Your Input: | |
| | CCDC62 | Coiled-coil domain containing 62. (692 aa) |
| | SLC30A9 | Uncharacterized protein. (541 aa) |
| | STRN | Striatin isoform X1. (809 aa) |
| | BUD31 | Protein BUD31 homolog isoform X2. (144 aa) |
| | NCOA3 | Uncharacterized protein. (1296 aa) |
| | NCOA6 | Nuclear receptor coactivator 6. (2061 aa) |
| | ASXL1 | ASXL transcriptional regulator 1. (1542 aa) |
| | GTF2B | General transcription factor IIB. (337 aa) |
| | LRIF1 | Ligand-dependent nuclear receptor-interacting factor 1 isoform X1. (762 aa) |
| | DCAF13 | DDB1 and CUL4 associated factor 13. (444 aa) |
| | FOXH1 | Forkhead box H1. (354 aa) |
| | NCOA7 | Nuclear receptor coactivator 7. (968 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (875 aa) |
| | PARK7 | DJ-1 protein. (189 aa) |
| | NR1H2 | Nuclear receptor subfamily 1 group H member 2. (458 aa) |
| | MED25 | Mediator complex subunit 25. (794 aa) |
| | DAXX | Death domain associated protein. (751 aa) |
| | CRX | Cone-rod homeobox. (345 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (434 aa) |
| | KDM5D | Lysine demethylase 5D. (1506 aa) |
| | DNAAF4 | Dynein axonemal assembly factor 4. (531 aa) |
| | RXRA | Retinoid X receptor alpha. (701 aa) |
| | WIPI1 | Uncharacterized protein. (477 aa) |
| | A0A5G2RAG6_PIG | Uncharacterized protein. (876 aa) |
| | NR1H4 | Nuclear receptor subfamily 1 group H member 4. (509 aa) |
| | TAF7L | TATA-box binding protein associated factor 7 like. (468 aa) |
| | GRIP1 | Glutamate receptor interacting protein 1. (1210 aa) |
| | MED17 | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (677 aa) |
| | NRIP1 | Nuclear receptor-interacting protein 1 isoform X1. (1156 aa) |
| | TACC2 | Uncharacterized protein. (2041 aa) |
| | NR4A3 | Nuclear receptor subfamily 4 group A member 3 isoform b. (643 aa) |
| | ZNF366 | Zinc finger protein 366. (740 aa) |
| | NKX3-1 | Homeobox protein Nkx-3.1 isoform 1. (247 aa) |
| | C1D | Uncharacterized protein. (141 aa) |
| | ARID1A | AT-rich interaction domain 1A. (2289 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (617 aa) |
| | A0A287BJ29_PIG | Uncharacterized protein. (118 aa) |
| | DDX54 | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (879 aa) |
| | TOB2 | Protein Tob2 isoform X1. (353 aa) |
| | VDR | Vitamin D3 receptor; Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (By similarity). Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (By similarity). The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes (By similarity). Plays a central role in calcium homeostasis (By similarity). (520 aa) |
| | LOC106506226 | TACC_C domain-containing protein. (378 aa) |
| | TCF21 | Transcription factor 21. (179 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | TGFB1I1 | Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (519 aa) |
| | SRARP | Steroid receptor associated and regulated protein. (170 aa) |
| | HIF1A | Hypoxia-inducible factor 1-alpha isoform 1. (824 aa) |
| | NRBF2 | Nuclear receptor binding factor 2. (288 aa) |
| | PKN1 | Protein kinase N1. (956 aa) |
| | DCAF1 | DDB1 and CUL4 associated factor 1. (1511 aa) |
| | NCOA1 | Nuclear receptor coactivator 1; Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone- dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating m [...] (1441 aa) |
| | PRPF6 | Pre-mRNA processing factor 6. (1150 aa) |
| | ARID5A | AT-rich interaction domain 5A. (846 aa) |
| | NSD1 | Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific isoform X1. (2701 aa) |
| | NR4A1 | Nuclear receptor subfamily 4 group A member 1 isoform 2. (598 aa) |
| | FOXP1 | Forkhead box P1. (692 aa) |
| | LATS1 | Large tumor suppressor kinase 1. (1146 aa) |
| | MED12 | Mediator complex subunit 12. (2187 aa) |
| | LOC100622504 | Uncharacterized protein. (469 aa) |
| | NCOA2 | Nuclear receptor coactivator. (1463 aa) |
| | ZBTB7A | Zinc finger and BTB domain containing 7A. (596 aa) |
| | ACTN4 | Actinin alpha 4. (1160 aa) |
| | TRIP4 | Thyroid hormone receptor interactor 4. (649 aa) |
| | NR4A2 | Nuclear receptor subfamily 4 group A member 2 isoform X1. (609 aa) |
| | MED4 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (271 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | KDM3A | Lysine demethylase 3A. (1323 aa) |
| | LCOR | Ligand dependent nuclear receptor corepressor. (1695 aa) |
| | MED30 | Mediator of RNA polymerase II transcription subunit 30 isoform 1. (185 aa) |
| | TACC1 | TACC_C domain-containing protein. (801 aa) |
| | SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (548 aa) |
| | PRMT2 | Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (435 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (429 aa) |
| | BCAS3 | BCAS3 microtubule associated cell migration factor. (950 aa) |
| | CRY1 | Cryptochrome circadian regulator 1. (588 aa) |
| | RARG | Retinoic acid receptor gamma. (554 aa) |
| | PPARGC1A | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Induces the expression of PERM1 in [...] (796 aa) |
| | CTNNB1 | Catenin beta 1. (808 aa) |
| | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1647 aa) |
| | ESR1 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (595 aa) |
| | TAF7 | Transcription initiation factor TFIID subunit 7. (349 aa) |
| | PADI2 | Peptidyl arginine deiminase 2. (689 aa) |
| | CNOT1 | CCR4-NOT transcription complex subunit 1. (2343 aa) |
| | THRAP3 | Thyroid hormone receptor-associated protein 3 isoform 1. (958 aa) |
| | RNF6 | Ring finger protein 6. (663 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (217 aa) |
| | BRD8 | Bromodomain containing 8. (1236 aa) |
| | EP300 | E1A binding protein p300. (2420 aa) |
| | SNW1 | SNW domain-containing protein 1 isoform 2. (536 aa) |
| | F1SDC8_PIG | Uncharacterized protein. (1369 aa) |
| | MED13 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2173 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1517 aa) |
| | MED24 | Mediator complex subunit 24. (1007 aa) |
| | SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa) |
| | STAT5B | Signal transducer and activator of transcription 5B; Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation. (787 aa) |
| | TRIM24 | Transcription intermediary factor 1-alpha isoform X1. (1050 aa) |
| | TRIM68 | Tripartite motif containing 68. (484 aa) |
| | PPARGC1B | Peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform 1. (1028 aa) |
| | RNF14 | RBR-type E3 ubiquitin transferase. (474 aa) |
| | CALR | Calreticulin; Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis; Belongs to the calreticulin family. (417 aa) |
| | MED16 | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (837 aa) |
| | MYOD1 | Myoblast determination protein 1; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity). (319 aa) |
| | GTF2H1 | General transcription factor IIH subunit 1. (674 aa) |
| | CRY2 | Cryptochrome circadian regulator 2. (615 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (470 aa) |
| | NR0B1 | Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily. (490 aa) |
| | NR1I2 | Nuclear receptor subfamily 1 group I member 2. (437 aa) |
| | TADA3 | Transcriptional adapter 3 isoform a. (432 aa) |
| | TMF1 | TATA element modulatory factor 1. (1096 aa) |
| | CTBP2 | C-terminal binding protein 2. (982 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (669 aa) |
| | MMS19 | MMS19 homolog, cytosolic iron-sulfur assembly component. (1039 aa) |
| | SIRT1 | NAD-dependent protein deacetylase sirtuin-1 isoform a. (742 aa) |
| | YWHAH | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa) |
| | PPID | Peptidylprolyl isomerase D. (370 aa) |
