Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACVRL1 | CAV1 | ENSSSCP00000000247 | ENSSSCP00000031700 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] | 0.436 |
| ACVRL1 | SPRY2 | ENSSSCP00000000247 | ENSSSCP00000069477 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Sprouty RTK signaling antagonist 2. | 0.480 |
| CAV1 | ACVRL1 | ENSSSCP00000031700 | ENSSSCP00000000247 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.436 |
| CAV1 | CCND1 | ENSSSCP00000031700 | ENSSSCP00000059262 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] | Cyclin D1; Belongs to the cyclin family. | 0.425 |
| CAV1 | CTNNB1 | ENSSSCP00000031700 | ENSSSCP00000031836 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] | Catenin beta 1. | 0.615 |
| CAV1 | MMP9 | ENSSSCP00000031700 | ENSSSCP00000049256 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] | Matrix metalloproteinase-9. | 0.445 |
| CAV1 | STAT1 | ENSSSCP00000031700 | ENSSSCP00000033087 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] | Signal transducer and activator of transcription 1; Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to [...] | 0.448 |
| CCND1 | CAV1 | ENSSSCP00000059262 | ENSSSCP00000031700 | Cyclin D1; Belongs to the cyclin family. | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] | 0.425 |
| CCND1 | CTNNB1 | ENSSSCP00000059262 | ENSSSCP00000031836 | Cyclin D1; Belongs to the cyclin family. | Catenin beta 1. | 0.745 |
| CCND1 | EZH2 | ENSSSCP00000059262 | ENSSSCP00000048035 | Cyclin D1; Belongs to the cyclin family. | Enhancer of zeste 2 polycomb repressive complex 2 subunit. | 0.571 |
| CCND1 | FGF10 | ENSSSCP00000059262 | ENSSSCP00000017886 | Cyclin D1; Belongs to the cyclin family. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.408 |
| CCND1 | JAG1 | ENSSSCP00000059262 | ENSSSCP00000007530 | Cyclin D1; Belongs to the cyclin family. | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | 0.655 |
| CCND1 | KRAS | ENSSSCP00000059262 | ENSSSCP00000021836 | Cyclin D1; Belongs to the cyclin family. | KRAS proto-oncogene, GTPase. | 0.675 |
| CCND1 | MMP9 | ENSSSCP00000059262 | ENSSSCP00000049256 | Cyclin D1; Belongs to the cyclin family. | Matrix metalloproteinase-9. | 0.725 |
| CCND1 | NOTCH1 | ENSSSCP00000059262 | ENSSSCP00000050060 | Cyclin D1; Belongs to the cyclin family. | Neurogenic locus notch homolog protein 1 preproprotein. | 0.668 |
| CCND1 | SMO | ENSSSCP00000059262 | ENSSSCP00000017553 | Cyclin D1; Belongs to the cyclin family. | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.456 |
| CCND1 | SOX9 | ENSSSCP00000059262 | ENSSSCP00000018278 | Cyclin D1; Belongs to the cyclin family. | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. | 0.505 |
| CCND1 | STAT1 | ENSSSCP00000059262 | ENSSSCP00000033087 | Cyclin D1; Belongs to the cyclin family. | Signal transducer and activator of transcription 1; Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to [...] | 0.645 |
| CCND1 | YAP1 | ENSSSCP00000059262 | ENSSSCP00000033204 | Cyclin D1; Belongs to the cyclin family. | Yes associated protein 1. | 0.449 |
| CCND1 | ZEB1 | ENSSSCP00000059262 | ENSSSCP00000029132 | Cyclin D1; Belongs to the cyclin family. | Zinc finger E-box binding homeobox 1. | 0.579 |
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