STRINGSTRING
SACM1L SACM1L TMX2 TMX2 GRAMD1A GRAMD1A PPP1R1B PPP1R1B GRAMD1B GRAMD1B TOMM40 TOMM40 VPS13A VPS13A ATG5 ATG5 PIK3R4 PIK3R4 GRAMD2A GRAMD2A ZFYVE1 ZFYVE1 MBOAT7 MBOAT7 ATG14 ATG14 CLCC1 CLCC1 PDZD8 PDZD8 GRAMD1C GRAMD1C OSBPL5 OSBPL5 MICOS13 MICOS13 C2CD2L C2CD2L ESYT3 ESYT3 ATG2A ATG2A LOC100627175 LOC100627175 MOSPD2 MOSPD2 BCAP31 BCAP31 TMEM41B TMEM41B AHCYL1 AHCYL1 STX17 STX17 SERAC1 SERAC1 ATG16L1 ATG16L1 STARD3 STARD3 SARAF SARAF TMCC1 TMCC1 FATE1 FATE1 CANX CANX RMDN3 RMDN3 RAB38 RAB38 ACSL4 ACSL4 STARD3NL STARD3NL LOC100153598 LOC100153598
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SACM1LSAC1 like phosphatidylinositide phosphatase. (596 aa)
TMX2Thioredoxin related transmembrane protein 2. (322 aa)
GRAMD1AGRAM domain containing 1A. (772 aa)
PPP1R1BProtein phosphatase 1 regulatory subunit 1B; Inhibitor of protein-phosphatase 1. (200 aa)
GRAMD1BGRAM domain containing 1B. (878 aa)
TOMM40Translocase of outer mitochondrial membrane 40. (400 aa)
VPS13AVacuolar protein sorting 13 homolog A. (3171 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3- like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is ess [...] (287 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1302 aa)
GRAMD2AGRAM domain-containing protein. (314 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (790 aa)
MBOAT7Membrane bound O-acyltransferase domain containing 7; Belongs to the membrane-bound acyltransferase family. (472 aa)
ATG14Autophagy related 14. (510 aa)
CLCC1Chloride channel CLIC like 1. (608 aa)
PDZD8PDZ domain-containing protein 8. (1154 aa)
GRAMD1CGRAM domain containing 1C. (664 aa)
OSBPL5Oxysterol-binding protein; Belongs to the OSBP family. (902 aa)
MICOS13MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Constituent of mature MICOS complex, it is required for the formation of cristae junction (CJ) and maintenance of cristae morphology. Required for the incorporation of MICOS10/MIC10 into the MICOS complex. (118 aa)
C2CD2LC2CD2 like. (707 aa)
ESYT3Extended synaptotagmin 3. (889 aa)
ATG2AAutophagy related 2A. (1929 aa)
LOC100627175GRAM domain-containing protein 2A isoform X1. (365 aa)
MOSPD2Motile sperm domain-containing protein 2 isoform 1. (518 aa)
BCAP31B-cell receptor-associated protein 31 isoform b. (246 aa)
TMEM41BTransmembrane protein 41B isoform X1. (291 aa)
AHCYL1Adenosylhomocysteinase-like protein 1; Belongs to the adenosylhomocysteinase family. (530 aa)
STX17Syntaxin-17 isoform X1; Belongs to the syntaxin family. (302 aa)
SERAC1Serine active site containing 1. (654 aa)
ATG16L1Autophagy-related protein 16-1 isoform X1. (623 aa)
STARD3StAR related lipid transfer domain containing 3. (550 aa)
SARAFStore-operated calcium entry-associated regulatory factor isoform X2. (336 aa)
TMCC1Uncharacterized protein. (657 aa)
FATE1Fetal and adult testis-expressed transcript protein homolog; Involved in the regulation of endoplasmic reticulum (ER)- mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling. (171 aa)
CANXCalnexin. (615 aa)
RMDN3Regulator of microtubule dynamics 3. (470 aa)
RAB38Ras-related protein Rab-32; Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and Mycobacterium. Plays an important role in the control of melanin production and melanosome biogenesis. In concert with RAB38, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes. Belongs to the small GTPase superfam [...] (211 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
STARD3NLSTARD3 N-terminal-like protein. (235 aa)
LOC100153598Uncharacterized protein. (294 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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