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COQ10A COQ10A VKORC1L1 VKORC1L1 CBR4 CBR4 LOC110256000 LOC110256000 SDHB SDHB NDUFS7 NDUFS7 NDUFS2 NDUFS2 TP53I3 TP53I3 SDHD SDHD COQ10B COQ10B ETFDH ETFDH VKORC1 VKORC1 AOC1 AOC1 LOC100520329 LOC100520329 HSD17B8 HSD17B8 AOC2 AOC2 ND4 ND4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
COQ10ACoenzyme Q10A. (243 aa)
VKORC1L1VKc domain-containing protein. (229 aa)
CBR4Carbonyl reductase 4; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (263 aa)
LOC110256000Amine oxidase; Belongs to the copper/topaquinone oxidase family. (751 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (328 aa)
NDUFS7Uncharacterized protein. (303 aa)
NDUFS2NADH dehydrogenase ubiquinone iron-sulfur protein 2, mitochondrial isoform 1; Belongs to the complex I 49 kDa subunit family. (473 aa)
TP53I3Tumor protein p53 inducible protein 3. (332 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (177 aa)
COQ10BCoenzyme Q10B. (244 aa)
ETFDHElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; Accepts electrons from ETF and reduces ubiquinone. (615 aa)
VKORC1Vitamin K epoxide reductase complex subunit 1. (163 aa)
AOC1Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis; Belongs to the copper/topaquinone oxidase family. (726 aa)
LOC100520329Amine oxidase. (742 aa)
HSD17B8Estradiol 17-beta-dehydrogenase 8; NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heterotetramer with CBR4 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (292 aa)
AOC2Amine oxidase. (755 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (459 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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