(11 nodes) UV-damage excision repair network (Sus scrofa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DDB1	Damage specific DNA binding protein 1. (1139 aa)
	INO80	INO80 complex ATPase subunit. (1566 aa)
	XPA	XPA, DNA damage recognition and repair factor. (310 aa)
	ACTR5	Actin-related protein 5; Belongs to the actin family. (608 aa)
	SIRT1	NAD-dependent protein deacetylase sirtuin-1 isoform a. (742 aa)
	XPC	XPC complex subunit, DNA damage recognition and repair factor. (1018 aa)
	DDB2	DNA damage-binding protein 2 isoform WT. (448 aa)
	MC1R	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a role in the regulation of eumelanin (black/brown) and phaeomelanin (red/yellow) synthesis; Belongs to the G-protein coupled receptor 1 family. (320 aa)
	POLD3	Uncharacterized protein. (463 aa)
	TREX1	Three prime repair exonuclease 1. (314 aa)
	CUL4B	Cullin 4B; Belongs to the cullin family. (1056 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTR5	INO80	ENSSSCP00000007827	ENSSSCP00000005125	Actin-related protein 5; Belongs to the actin family.	INO80 complex ATPase subunit.	0.990
CUL4B	DDB1	ENSSSCP00000013401	ENSSSCP00000013928	Cullin 4B; Belongs to the cullin family.	Damage specific DNA binding protein 1.	0.999
CUL4B	DDB2	ENSSSCP00000013401	ENSSSCP00000041359	Cullin 4B; Belongs to the cullin family.	DNA damage-binding protein 2 isoform WT.	0.901
CUL4B	POLD3	ENSSSCP00000013401	ENSSSCP00000019258	Cullin 4B; Belongs to the cullin family.	Uncharacterized protein.	0.499
CUL4B	XPA	ENSSSCP00000013401	ENSSSCP00000005761	Cullin 4B; Belongs to the cullin family.	XPA, DNA damage recognition and repair factor.	0.610
CUL4B	XPC	ENSSSCP00000013401	ENSSSCP00000041133	Cullin 4B; Belongs to the cullin family.	XPC complex subunit, DNA damage recognition and repair factor.	0.817
DDB1	CUL4B	ENSSSCP00000013928	ENSSSCP00000013401	Damage specific DNA binding protein 1.	Cullin 4B; Belongs to the cullin family.	0.999
DDB1	DDB2	ENSSSCP00000013928	ENSSSCP00000041359	Damage specific DNA binding protein 1.	DNA damage-binding protein 2 isoform WT.	0.999
DDB1	POLD3	ENSSSCP00000013928	ENSSSCP00000019258	Damage specific DNA binding protein 1.	Uncharacterized protein.	0.504
DDB1	TREX1	ENSSSCP00000013928	ENSSSCP00000019230	Damage specific DNA binding protein 1.	Three prime repair exonuclease 1.	0.455
DDB1	XPA	ENSSSCP00000013928	ENSSSCP00000005761	Damage specific DNA binding protein 1.	XPA, DNA damage recognition and repair factor.	0.790
DDB1	XPC	ENSSSCP00000013928	ENSSSCP00000041133	Damage specific DNA binding protein 1.	XPC complex subunit, DNA damage recognition and repair factor.	0.789
DDB2	CUL4B	ENSSSCP00000041359	ENSSSCP00000013401	DNA damage-binding protein 2 isoform WT.	Cullin 4B; Belongs to the cullin family.	0.901
DDB2	DDB1	ENSSSCP00000041359	ENSSSCP00000013928	DNA damage-binding protein 2 isoform WT.	Damage specific DNA binding protein 1.	0.999
DDB2	XPA	ENSSSCP00000041359	ENSSSCP00000005761	DNA damage-binding protein 2 isoform WT.	XPA, DNA damage recognition and repair factor.	0.960
DDB2	XPC	ENSSSCP00000041359	ENSSSCP00000041133	DNA damage-binding protein 2 isoform WT.	XPC complex subunit, DNA damage recognition and repair factor.	0.933
INO80	ACTR5	ENSSSCP00000005125	ENSSSCP00000007827	INO80 complex ATPase subunit.	Actin-related protein 5; Belongs to the actin family.	0.990
POLD3	CUL4B	ENSSSCP00000019258	ENSSSCP00000013401	Uncharacterized protein.	Cullin 4B; Belongs to the cullin family.	0.499
POLD3	DDB1	ENSSSCP00000019258	ENSSSCP00000013928	Uncharacterized protein.	Damage specific DNA binding protein 1.	0.504
SIRT1	XPA	ENSSSCP00000010911	ENSSSCP00000005761	NAD-dependent protein deacetylase sirtuin-1 isoform a.	XPA, DNA damage recognition and repair factor.	0.402