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| | SCCPDH | Sacchrp_dh_NADP domain-containing protein. (429 aa) |
| | PYCR2 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa) |
| | CTBP2 | C-terminal binding protein 2. (982 aa) |
| | RDH5 | Retinol dehydrogenase 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (429 aa) |
| | SDR9C7 | Short chain dehydrogenase/reductase family 9C member 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (313 aa) |
| | LDHB | L-lactate dehydrogenase B chain; Belongs to the LDH/MDH superfamily. LDH family. (377 aa) |
| | PYROXD1 | Pyridine nucleotide-disulphide oxidoreductase domain 1. (502 aa) |
| | NDUFA9 | NADH:ubiquinone oxidoreductase subunit A9. (407 aa) |
| | MTHFD1 | Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (935 aa) |
| | RDH11 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (306 aa) |
| | RDH12 | Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa) |
| | AK7 | Adenylate kinase 7 isoform 1. (724 aa) |
| | HSD11B2 | Hydroxysteroid 11-beta dehydrogenase 2. (400 aa) |
| | GAPDHS | Glyceraldehyde-3-phosphate dehydrogenase. (403 aa) |
| | BAX | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Belongs to the Gfo/Idh/MocA family. (480 aa) |
| | DHRS3 | Short-chain dehydrogenase/reductase 3 isoform 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa) |
| | GRHPR | Glyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (328 aa) |
| | HSD17B7 | Hydroxysteroid 17-beta dehydrogenase 7. (334 aa) |
| | HSD3B1 | 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. (373 aa) |
| | SDR42E2 | Short chain dehydrogenase/reductase family 42E, member 2. (417 aa) |
| | UXS1 | UDP-glucuronate decarboxylase 1. (460 aa) |
| | SUCLG1 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (393 aa) |
| | LOC100513982 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa) |
| | MTHFD2 | Uncharacterized protein. (378 aa) |
| | HADHA | Trifunctional enzyme subunit alpha, mitochondrial; Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional en [...] (763 aa) |
| | TP53I3 | Tumor protein p53 inducible protein 3. (332 aa) |
| | RDH14 | Retinol dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (336 aa) |
| | MTHFD2L | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (346 aa) |
| | ADH4 | Alcohol dehydrogenase 4 isoform 2. (380 aa) |
| | TGDS | dTDP-D-glucose 4,6-dehydratase isoform X1. (389 aa) |
| | HPGD | 15-hydroxyprostaglandin dehydrogenase NAD(+) isoform 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa) |
| | GLUD1 | Glutamate dehydrogenase 1, mitochondrial; Mitochondrial glutamate dehydrogenase that converts L- glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity). (558 aa) |
| | TSTA3 | Tissue specific transplantation antigen P35B. (448 aa) |
| | CRYM | Crystallin mu. (321 aa) |
| | DHRSX | Uncharacterized protein. (338 aa) |
| | A0A5G2RCU2_PIG | Ldh_1_N domain-containing protein. (146 aa) |
| | AHCY | Adenosylhomocysteinase; Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. (488 aa) |
| | ME1 | NADP-dependent malic enzyme; Belongs to the malic enzymes family. (571 aa) |
| | HSDL2 | Hydroxysteroid dehydrogenase like 2. (418 aa) |
| | MDH2 | Malate dehydrogenase, mitochondrial. (395 aa) |
| | GPD1L | Glycerol-3-phosphate dehydrogenase [NAD(+)]. (376 aa) |
| | DECR1 | Uncharacterized protein. (348 aa) |
| | WWOX | WW domain containing oxidoreductase. (414 aa) |
| | HIBADH | 3-hydroxyisobutyrate dehydrogenase. (377 aa) |
| | RTN4IP1 | Reticulon 4 interacting protein 1. (476 aa) |
| | PYCR1 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (385 aa) |
| | MAT2B | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (370 aa) |
| | CBR4 | Carbonyl reductase 4; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (263 aa) |
| | SDR39U1 | Short chain dehydrogenase/reductase family 39U member 1. (298 aa) |
| | H6PD | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (812 aa) |
| | A0A5G2R2V5_PIG | Uncharacterized protein. (72 aa) |
| | GMDS | GDP-mannose 4,6-dehydratase. (390 aa) |
| | VAT1L | Vesicle amine transport 1 like. (432 aa) |
| | PHGDH | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (547 aa) |
| | MDH1 | Malate dehydrogenase, cytoplasmic. (352 aa) |
| | SDR16C5 | Short chain dehydrogenase/reductase family 16C, member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa) |
| | LDHB-2 | L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa) |
| | DHRS7 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (355 aa) |
| | UEVLD | UEV and lactate/malate dehyrogenase domains. (471 aa) |
| | ADH1C | PKS_ER domain-containing protein. (388 aa) |
| | CBR2 | Carbonyl reductase [NADPH] 2; May function in the pulmonary metabolism of endogenous carbonyl compounds, such as aliphatic aldehydes and ketones derived from lipid peroxidation, 3-ketosteroids and fatty aldehydes, as well as in xenobiotic metabolism; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa) |
| | G6PD | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (649 aa) |
| | DECR2 | Peroxisomal 2,4-dienoyl-CoA reductase. (320 aa) |
| | A0A287BRI4_PIG | Uncharacterized protein. (214 aa) |
| | BLVRA | Biliverdin reductase A. (438 aa) |
| | GALE | UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (358 aa) |
| | FAR1 | Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (535 aa) |
| | A0A287BB58_PIG | Uncharacterized protein. (292 aa) |
| | HSD17B2 | Estradiol 17-beta-dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (388 aa) |
| | HADH | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; Plays an essential role in the mitochondrial beta-oxidation of short chain fatty acids. Exerts it highest activity toward 3- hydroxybutyryl-CoA; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (314 aa) |
| | AASS | Aminoadipate-semialdehyde synthase. (961 aa) |
| | GFOD1 | Glucose-fructose oxidoreductase domain-containing protein 1 isoform 1. (390 aa) |
| | CBR1 | Carbonyl reductase [NADPH] 1; NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity). (289 aa) |
| | CRYL1 | Lambda-crystallin homolog. (369 aa) |
| | FAR2 | Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (515 aa) |
| | ADH5 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (392 aa) |
| | ISYNA1 | Inositol-3-phosphate synthase 1. (556 aa) |
| | STEAP3 | STEAP3 metalloreductase. (526 aa) |
| | A0A287AV28_PIG | Glycerol-3-phosphate dehydrogenase [NAD(+)]. (347 aa) |
| | LOC102159510 | Dehydrogenase/reductase SDR family member on chromosome X. (335 aa) |
| | NOXRED1 | NADP dependent oxidoreductase domain containing 1. (366 aa) |
| | MTHFD1L | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (975 aa) |
| | NSDHL | Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family. (363 aa) |
| | A0A287AS76_PIG | NmrA domain-containing protein. (293 aa) |
| | NNT | Nicotinamide nucleotide transhydrogenase. (1113 aa) |
| | KCNT2 | Potassium sodium-activated channel subfamily T member 2. (1149 aa) |
| | LOC110262184 | Uncharacterized protein. (397 aa) |
| | LOC100626876 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (315 aa) |
| | PTGR2 | Prostaglandin reductase 2 isoform X1. (351 aa) |
| | QDPR | Dihydropteridine reductase; The product of this enzyme, tetrahydrobiopterin (BH-4), is an essential cofactor for phenylalanine, tyrosine, and tryptophan hydroxylases; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (236 aa) |
| | CRYZ | Quinone oxidoreductase; Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding (By similarity). (330 aa) |
| | HSD17B1 | 17-beta-hydroxysteroid dehydrogenase type 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (321 aa) |
| | KDSR | 3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (337 aa) |
| | SDR42E1 | Short-chain dehydrogenase/reductase family 42E member 1 isoform X1; Belongs to the 3-beta-HSD family. (394 aa) |
| | ZADH2 | Zinc binding alcohol dehydrogenase domain containing 2. (377 aa) |
| | LOC100157017 | Glyoxylate reductase/hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (346 aa) |
| | CTBP1 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (428 aa) |
| | LOC110261008 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (308 aa) |
| | PTGR1 | Prostaglandin reductase 1; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha. Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4. (329 aa) |
| | GLYR1 | Glyoxylate reductase 1 homolog. (581 aa) |
| | PYCR3 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (277 aa) |
| | DHRS1 | Dehydrogenase/reductase SDR family member 1. (324 aa) |
| | RDH16 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa) |
| | LDHA | L-lactate dehydrogenase A chain. (443 aa) |
| | HSD3B7 | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7. (410 aa) |
| | RDH13 | Retinol dehydrogenase 13 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (334 aa) |
| | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (398 aa) |
| | RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa) |
| | HSDL1 | Inactive hydroxysteroid dehydrogenase-like protein 1 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa) |
| | DHRS4 | Dehydrogenase/reductase SDR family member 4; Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha- dicarbonyl compounds with aromatic rings, such as pyrimidine-4- aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4- hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones. (279 aa) |
| | DCXR | Dicarbonyl and L-xylulose reductase. (244 aa) |
| | ME2 | Malic enzyme. (678 aa) |
| | KCNMA1 | Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] (1288 aa) |
| | AHCYL1 | Adenosylhomocysteinase-like protein 1; Belongs to the adenosylhomocysteinase family. (530 aa) |
| | DHRS7C | Dehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (308 aa) |
| | GPD1 | Glycerol-3-phosphate dehydrogenase [NAD(+)]. (404 aa) |
| | HSD17B10 | Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (293 aa) |
| | HSD17B8 | Estradiol 17-beta-dehydrogenase 8; NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heterotetramer with CBR4 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (292 aa) |
| | TDH | L-threonine 3-dehydrogenase, mitochondrial; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate, mediating L-threonine catabolism. (373 aa) |
| | BLVRB | Flavin reductase (NADPH). (206 aa) |
| | CRYZL1 | Crystallin zeta like 1. (334 aa) |
| | KCNU1 | Potassium calcium-activated channel subfamily U member 1. (1058 aa) |
| | HSD17B12 | Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa) |
| | EHHADH | Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (731 aa) |
| | UGDH | UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa) |
| | HSD17B6 | Hydroxysteroid 17-beta dehydrogenase 6; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa) |
| | BDH2 | 3-hydroxybutyrate dehydrogenase type 2 isoform X2. (245 aa) |
| | HSD11B1L | Hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform b. (293 aa) |
| | HSD17B4 | Peroxisomal multifunctional enzyme type 2 isoform 2. (737 aa) |
| | GFOD2 | Glucose-fructose oxidoreductase domain-containing protein 2 isoform 1. (385 aa) |
| | FASN | Uncharacterized protein. (1430 aa) |
| | VAT1 | Synaptic vesicle membrane protein VAT-1 homolog. (400 aa) |
| | PECR | Peroxisomal trans-2-enoyl-CoA reductase. (303 aa) |
| | HSD17B11 | Hydroxysteroid 17-beta dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa) |
| | DHRS13 | Dehydrogenase/reductase 13. (454 aa) |
| | MRM1 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (396 aa) |
| | ACLY | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1130 aa) |
| | AHCYL2 | Adenosylhomocysteinase like 2; Belongs to the adenosylhomocysteinase family. (645 aa) |
| | HSD11B1 | Corticosteroid 11-beta-dehydrogenase isozyme 1. (292 aa) |
| | STEAP4 | Metalloreductase STEAP4. (470 aa) |
| | ME3 | Malic enzyme. (604 aa) |
| | RDH8 | Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (331 aa) |
| | LDHC | L-lactate dehydrogenase C chain; Possible role in sperm motility. (332 aa) |
| | HTATIP2 | HIV-1 Tat interactive protein 2. (280 aa) |
| | CBR3 | Carbonyl reductase NADPH 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (277 aa) |
| | BDH1 | D-beta-hydroxybutyrate dehydrogenase, mitochondrial; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (346 aa) |
| | HSD17B3 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (310 aa) |
