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| | ADRA2C | Adrenoceptor alpha 2C. (460 aa) |
| | SCTR | Secretin receptor; Belongs to the G-protein coupled receptor 2 family. (443 aa) |
| | TAS2R3 | Taste receptor type 2. (316 aa) |
| | TAS2R4 | Taste receptor type 2. (296 aa) |
| | LTB4R | Leukotriene B4 receptor; Belongs to the G-protein coupled receptor 1 family. (351 aa) |
| | TAS2R39 | Taste 2 receptor member 39; Belongs to the G-protein coupled receptor T2R family. (375 aa) |
| | HTR6 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (439 aa) |
| | CCR6 | C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (376 aa) |
| | ADGRE3 | Adhesion G protein-coupled receptor E3; Belongs to the G-protein coupled receptor 2 family. (642 aa) |
| | LOC494564 | Medium-wave-sensitive opsin. (364 aa) |
| | CCL17 | C-C motif chemokine. (102 aa) |
| | ADORA2B | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa) |
| | HTR1F | 5-hydroxytryptamine receptor 1F isoform X1. (366 aa) |
| | HRH2 | Histamine H2 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (423 aa) |
| | CCL2 | C-C motif chemokine 2; Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-d [...] (99 aa) |
| | CCL11 | C-C motif chemokine. (97 aa) |
| | CCL1 | C-C motif chemokine. (94 aa) |
| | CCL3L1 | C-C motif chemokine. (126 aa) |
| | CCR7 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (477 aa) |
| | HCRT | Orexin-A; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity (By similarity). (131 aa) |
| | RAMP2 | Receptor activity-modifying protein 2. (177 aa) |
| | CRHR1 | Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (415 aa) |
| | SSTR2 | Somatostatin receptor type 2; Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 [...] (360 aa) |
| | NMUR2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (410 aa) |
| | ADRA1B | Adrenoceptor alpha 1B. (518 aa) |
| | CCL28 | C-C motif chemokine. (176 aa) |
| | NPSR1 | Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (369 aa) |
| | OPN1SW | G_PROTEIN_RECEP_F1_2 domain-containing protein. (351 aa) |
| | TAS2R60 | Taste receptor type 2. (314 aa) |
| | TAS2R41 | Taste receptor type 2. (307 aa) |
| | RAMP1 | Receptor activity-modifying protein 1; Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL (By similarity). (271 aa) |
| | ACKR3 | Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa) |
| | CXCR2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (382 aa) |
| | F1SS05_PIG | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (343 aa) |
| | PTH2R | Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. (550 aa) |
| | GCG | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] (180 aa) |
| | ADRB3 | Beta-3 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta- 3 is involved in the regulation of lipolysis and thermogenesis; Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily. (407 aa) |
| | AVPR1B | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (422 aa) |
| | GRM3 | Glutamate metabotropic receptor 3. (879 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa) |
| | CXCR5 | C-X-C chemokine receptor type 5 isoform 1; Belongs to the G-protein coupled receptor 1 family. (373 aa) |
| | MTNR1B | Melatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family. (364 aa) |
| | CRHBP | Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa) |
| | F2RL1 | Proteinase-activated receptor 2 preproprotein. (397 aa) |
| | GRM6 | Glutamate metabotropic receptor 6. (872 aa) |
| | INSL3 | Insulin-like 3 A chain; Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor (By similarity); Belongs to the insulin family. (131 aa) |
| | PTGER1 | Prostaglandin E receptor 1. (405 aa) |
| | RLN3 | Relaxin-3 A chain; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 and relaxin-3 receptor-2 (By similarity). (140 aa) |
| | S1PR4 | Sphingosine 1-phosphate receptor 4. (437 aa) |
| | KISS1R | G protein-coupled receptor 54. (399 aa) |
| | ADM | Proadrenomedullin N-20 terminal peptide; AM and PAMP are potent hypotensive and vasodilatator agents. (188 aa) |
| | PTH | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity). (115 aa) |
| | CRSP3 | Calcitonin receptor-stimulating peptide 3; Belongs to the calcitonin family. (125 aa) |
| | FSHB | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. (129 aa) |
| | CHRM4 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (479 aa) |
| | PTGDR2 | Prostaglandin D2 receptor 2; Belongs to the G-protein coupled receptor 1 family. (464 aa) |
| | GPHA2 | Glycoprotein hormone subunit alpha 2. (129 aa) |
| | DRD4 | Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (333 aa) |
| | AGTR2 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (362 aa) |
| | P2RY4 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (365 aa) |
| | GRPR | Gastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family. (395 aa) |
| | GPR143 | Uncharacterized protein. (405 aa) |
| | DRD3 | Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (447 aa) |
| | P2RY1 | Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (371 aa) |
| | P2RY12 | Purinergic receptor P2Y12. (339 aa) |
| | ACKR4 | Chemokine (C-C motif) receptor-like protein 1; Belongs to the G-protein coupled receptor 1 family. (350 aa) |
| | TRH | Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (241 aa) |
| | RHO | Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity). (348 aa) |
| | GRM2 | Glutamate metabotropic receptor 2. (872 aa) |
| | CCR1 | Chemokine (C-C motif) receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa) |
| | CXCR6 | Chemokine (C-X-C motif) receptor 6; Belongs to the G-protein coupled receptor 1 family. (341 aa) |
| | CCK | Cholecystokinin-58 desnonopeptide; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. (154 aa) |
| | CCL27 | C-C motif chemokine 27. (107 aa) |
| | CCL19 | C-C motif chemokine. (100 aa) |
| | NPS | Neuropeptide S. (89 aa) |
| | ADRA2A | Alpha-2A adrenergic receptor; Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. (465 aa) |
| | PPYR1 | Neuropeptide Y-family receptor Y4; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | RGR | Retinal G protein coupled receptor; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (310 aa) |
| | NPFFR1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (432 aa) |
| | TACR2 | Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (404 aa) |
| | ADORA2A | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (414 aa) |
| | HCAR1 | Hydroxycarboxylic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (340 aa) |
| | GNRH1 | GnRH-associated peptide 1; Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones; Belongs to the GnRH family. (91 aa) |
| | S1PR3 | Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (377 aa) |
| | EDNRB | Endothelin receptor type B; Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRB sub-subfamily. (443 aa) |
| | RRH | Retinal pigment epithelium-derived rhodopsin homolog; Belongs to the G-protein coupled receptor 1 family. (336 aa) |
| | QRFPR | Pyroglutamylated RFamide peptide receptor; Belongs to the G-protein coupled receptor 1 family. (431 aa) |
| | AMCF-II | Alveolar macrophage chemotactic factor 2; Has chemotactic activity for porcine, and in a lesser extent, for human neutrophils; Belongs to the intercrine alpha (chemokine CxC) family. (117 aa) |
| | CXCL8 | Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus; Belongs to the intercrine alpha (chemokine CxC) family. (103 aa) |
| | NPFFR2 | Neuropeptide FF receptor 2; Belongs to the G-protein coupled receptor 1 family. (418 aa) |
| | NPY5R | Neuropeptide Y receptor type 5; Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders (By similarity); Belongs to the G-protein coupled receptor 1 family. (446 aa) |
| | DRD5 | Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (471 aa) |
| | NTSR2 | Neurotensin receptor 2; Belongs to the G-protein coupled receptor 1 family. (408 aa) |
| | LHCGR | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (696 aa) |
| | ADRA2B | Alpha-2B adrenergic receptor. (446 aa) |
| | GNG13 | G protein subunit gamma 13. (67 aa) |
| | GNB2 | G protein subunit beta 2. (340 aa) |
| | MC3R | Melanocortin-3 receptor. (319 aa) |
| | OXT | Oxytocin-neurophysin 1; Neurophysin 1 specifically binds oxytocin. (125 aa) |
| | AVP | Vasopressin-neurophysin 2-copeptin. (217 aa) |
| | ADRA1D | Alpha-1D adrenergic receptor; This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium. (570 aa) |
| | PLPPR4 | Phospholipid phosphatase-related protein type 4 isoform 1. (715 aa) |
| | PROK1 | Prokineticin 1. (105 aa) |
| | TSHB | Thyrotropin subunit beta; Indispensable for the control of thyroid structure and metabolism. (138 aa) |
| | GNRHR2 | Gonadotropin-releasing hormone receptor isoform 1. (293 aa) |
| | RXFP4 | Relaxin-3/INSL7 receptor 2. (373 aa) |
| | XCL1 | Lymphotactin isoform X1. (110 aa) |
| | OPRK1 | Opioid receptor kappa 1; Belongs to the G-protein coupled receptor 1 family. (380 aa) |
| | PENK | Proenkephalin. (274 aa) |
| | CRH | Corticoliberin; Hormone regulating the release of corticotropin from pituitary gland. Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity); Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family. (191 aa) |
| | QRFP | Pyroglutamylated RFamide peptide. (134 aa) |
| | GPHB5 | Glycoprotein hormone subunit beta 5. (166 aa) |
| | MCHR2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (339 aa) |
| | LPAR3 | Lysophosphatidic acid receptor 3 isoform X1; Belongs to the G-protein coupled receptor 1 family. (354 aa) |
| | ECE1 | Endothelin converting enzyme 1. (771 aa) |
| | CORT | Somatostatin domain-containing protein. (108 aa) |
| | TAS1R1 | Taste 1 receptor member 1. (844 aa) |
| | TAS1R3 | G_PROTEIN_RECEP_F3_4 domain-containing protein. (855 aa) |
| | PTH2 | Parathyroid hormone 2. (98 aa) |
| | C5AR2 | Complement component 5a receptor 2. (434 aa) |
| | FFAR1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (566 aa) |
| | CCL22 | C-C motif chemokine. (93 aa) |
| | SSTR1 | Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa) |
| | GRM4 | Glutamate metabotropic receptor 4. (966 aa) |
| | HCRTR2 | Orexin receptor type 2; Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides. Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding. (444 aa) |
| | NTS | Neurotensin/neuromedin N preproprotein. (171 aa) |
| | PMCH | Pro-MCH preproprotein. (165 aa) |
| | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1. (340 aa) |
| | TAS2R9 | Taste receptor type 2. (311 aa) |
| | TAC3 | Neurokinin-B; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Is a critical central regulator of gonadal function (By similarity); Belongs to the tachykinin family. (126 aa) |
| | NPFF | Neuropeptide FF-amide peptide precursor. (114 aa) |
| | GALR3 | Galanin receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa) |
| | CXCL11 | C-X-C motif chemokine. (129 aa) |
| | SSTR3 | Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (421 aa) |
| | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (361 aa) |
| | NPW | Neuropeptide W-23; Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress (By similarity); Belongs to the neuropeptide B/W family. (152 aa) |
| | CRHR2 | Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (482 aa) |
| | PTH1R | Parathyroid hormone/parathyroid hormone-related peptide receptor; Receptor for parathyroid hormone and for parathyroid hormone- related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 2 family. (641 aa) |
| | GPR37 | G protein-coupled receptor 37. (614 aa) |
| | GNG10 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | PPBP | Platelet basic protein; Chemoattractant factor for neutrophils. (159 aa) |
| | LTB4R2 | Leukotriene B4 receptor 2. (358 aa) |
| | APLN | Apelin. (77 aa) |
| | GALR1 | Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family. (349 aa) |
| | NMUR1 | Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family. (556 aa) |
| | GCGR | G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor 2 family. (602 aa) |
| | GABBR1 | Gamma-aminobutyric acid type B receptor subunit 1. (1247 aa) |
| | KEL | Kell metallo-endopeptidase (Kell blood group). (763 aa) |
| | LOC100621431 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (234 aa) |
| | GLP1R | Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (468 aa) |
| | CNR1 | Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (472 aa) |
| | CCL25 | C-C motif chemokine 25; Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4 (By similarity); Belongs to the intercrine beta (chemokine CC) family. (220 aa) |
| | HTR7 | 5-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family. (475 aa) |
| | S1PR2 | Sphingosine 1-phosphate receptor 2. (351 aa) |
| | CCL4 | C-C motif chemokine 4; Monokine with inflammatory and chemokinetic properties. (96 aa) |
| | EDN3 | Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides. Belongs to the endothelin/sarafotoxin family. (231 aa) |
| | CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa) |
| | CCRL2 | Chemokine C-C motif receptor-like 2; Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine- triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptor. Plays a critical role for the development of Th2 responses (By similarity). (350 aa) |
| | ADORA3 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (348 aa) |
| | GPR35 | G protein-coupled receptor 35; Belongs to the G-protein coupled receptor 1 family. (304 aa) |
| | GIPR | Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa) |
| | S1PR5 | Sphingosine 1-phosphate receptor 5; Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/O)alpha and G(12) subclass of heteromeric G-proteins (By similarity). (463 aa) |
| | GPR183 | G-protein coupled receptor 183 isoform X1; Belongs to the G-protein coupled receptor 1 family. (356 aa) |
| | ACKR2 | Atypical chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (385 aa) |
| | GABBR2 | Gamma-aminobutyric acid type B receptor subunit 2. (958 aa) |
| | CNR2 | Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. (360 aa) |
| | CCR10 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | UBA6 | Gonadotropin-releasing hormone receptor; Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G- proteins that activate a phosphatidylinositol-calcium second messenger system. (1396 aa) |
| | CMKLR1 | Chemokine-like receptor 1; Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism (By similarity). (363 aa) |
| | CCL16 | C-C motif chemokine. (120 aa) |
| | PRLH | Prolactin releasing hormone. (87 aa) |
| | CXCR4 | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] (353 aa) |
| | OPN4 | Opsin 4. (488 aa) |
| | CALCR | Calcitonin receptor; This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. The receptor can also couple to an additional signaling pathway via a pertussis toxin-sensitive g protein in isolated osteoclasts and in LLC-PK1 cells; Belongs to the G-protein coupled receptor 2 family. (490 aa) |
| | NPB | Uncharacterized protein. (176 aa) |
| | TACR3 | Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (463 aa) |
| | NMBR | Neuromedin B receptor; Belongs to the G-protein coupled receptor 1 family. (390 aa) |
| | KISS1 | KiSS-1 metastasis-suppressor. (138 aa) |
| | P2RY6 | Pyrimidinergic receptor P2Y6. (515 aa) |
| | NLN | Neurolysin, mitochondrial; Binds angiotensins and its analogs; Belongs to the peptidase M3 family. (745 aa) |
| | GPR17 | G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family. (339 aa) |
| | PNOC | Nociceptin. (203 aa) |
| | UTS2B | Urotensin 2B. (119 aa) |
| | NTSR1 | Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (417 aa) |
| | HRH3 | Histamine receptor H3; Belongs to the G-protein coupled receptor 1 family. (455 aa) |
| | P2RY14 | Purinergic receptor P2Y14. (338 aa) |
| | CHRM2 | Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition; Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM2 sub-subfamily. (466 aa) |
| | BRS3 | Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family. (399 aa) |
| | SST | Somatostatin-14; [Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH- stimulated secretion of GH1 and LH; the inhibition of ghrelin- stimulated secretion of GH1 can be further increased by neuronostatin. (116 aa) |
| | CHRM5 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (508 aa) |
| | PROKR1 | Prokineticin receptor 1; Belongs to the G-protein coupled receptor 1 family. (393 aa) |
| | DRD2 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (455 aa) |
| | GPR132 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (430 aa) |
| | F2RL2 | Coagulation factor II thrombin receptor like 2; Belongs to the G-protein coupled receptor 1 family. (378 aa) |
| | ACKR1 | Atypical chemokine receptor 1 isoform b. (373 aa) |
| | TAS2R10 | Taste receptor type 2. (309 aa) |
| | PLPPR2 | Phospholipid phosphatase related 2. (427 aa) |
| | GAL | Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family. (337 aa) |
| | GPRC6A | G protein-coupled receptor class C group 6 member A. (928 aa) |
| | UTS2R | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (372 aa) |
| | GNRH2 | Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (119 aa) |
| | GNB1 | G protein subunit beta 1. (395 aa) |
| | LPAR1 | Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa) |
| | PLPPR1 | Phospholipid phosphatase related 1. (347 aa) |
| | GRM1 | Glutamate metabotropic receptor 1. (1195 aa) |
| | ADRA1A | Alpha-1A adrenergic receptor isoform 1. (466 aa) |
| | CGA | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. (144 aa) |
| | TRHR | Thyrotropin-releasing hormone receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (398 aa) |
| | PTGFR | Prostaglandin F2-alpha receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (362 aa) |
| | CXCL9 | C-X-C motif chemokine. (126 aa) |
| | GRM7 | Metabotropic glutamate receptor 7 isoform X1. (921 aa) |
| | CHRM3 | Muscarinic acetylcholine receptor M3; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. (590 aa) |
| | PTHLH | Parathyroid hormone like hormone. (209 aa) |
| | PLPPR5 | Phospholipid phosphatase related 5. (332 aa) |
| | UCN2 | Urocortin 2. (112 aa) |
| | PLPPR3 | Phospholipid phosphatase-related protein type 3 isoform 2. (756 aa) |
| | PRLHR | Prolactin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (370 aa) |
| | ADCYAP1R1 | Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family. (468 aa) |
| | TAS1R2 | Taste 1 receptor member 2. (836 aa) |
| | GPBAR1 | G protein-coupled bile acid receptor 1. (329 aa) |
| | P2RY2 | P2Y purinoceptor 2; Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP > ATP. (373 aa) |
| | LOC110255211 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (125 aa) |
| | A0A287ACS9_PIG | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (65 aa) |
| | VIPR2 | Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (465 aa) |
| | LPAR5 | Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (367 aa) |
| | CASR | Extracellular calcium-sensing receptor; G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis. Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands (By similarity). The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. The G-protein- coupled receptor activity is activated by a co-agonist mechanism: aromatic amino acids, such as [...] (1089 aa) |
| | TAS2R16 | Taste receptor type 2. (300 aa) |
| | HCAR2 | Hydroxycarboxylic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (363 aa) |
| | APLNR | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (383 aa) |
| | ADORA1 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa) |
| | CXCL13 | C-X-C motif chemokine. (111 aa) |
| | NPBWR2 | Neuropeptides B and W receptor 2; Belongs to the G-protein coupled receptor 1 family. (298 aa) |
| | LHB-2 | Lutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. (173 aa) |
| | GPR55 | G-protein coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (361 aa) |
| | LOC100154902 | Taste receptor type 2. (350 aa) |
| | EDN2 | Endothelin 2. (180 aa) |
| | TAC1 | Tachykinin precursor 1. (130 aa) |
| | TBXA2R | Thromboxane A2 receptor. (343 aa) |
| | P2RY13 | Purinergic receptor P2Y13; Belongs to the G-protein coupled receptor 1 family. (333 aa) |
| | GPR143-2 | Uncharacterized protein. (412 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | CCR9 | Chemokine (C-C motif) receptor 9 isoform A; Belongs to the G-protein coupled receptor 1 family. (369 aa) |
| | RXFP3 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (458 aa) |
| | CCL21 | Putative CCL21 chemokine. (134 aa) |
| | LPAR2 | Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa) |
| | GPR37L1 | G protein-coupled receptor 37 like 1. (459 aa) |
| | AVPR1A | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (423 aa) |
| | GPR18 | N-arachidonyl glycine receptor; Belongs to the G-protein coupled receptor 1 family. (331 aa) |
| | TAS2R7 | Taste receptor type 2. (312 aa) |
| | F2R | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (427 aa) |
| | RXFP1 | Relaxin family peptide receptor 1. (785 aa) |
| | ADGRE1 | Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (1474 aa) |
| | S1PR1 | Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa) |
| | SSTR5 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (305 aa) |
| | CCR4 | C-C chemokine receptor type 4 isoform X1; Belongs to the G-protein coupled receptor 1 family. (360 aa) |
| | HRH1 | Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. (506 aa) |
| | TACR1 | Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (394 aa) |
| | CD55 | Uncharacterized protein. (609 aa) |
| | GLP2R | Glucagon like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family. (556 aa) |
| | FFAR2 | Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (353 aa) |
| | CCL8 | C-C motif chemokine 8; Chemotactic factor that attracts monocytes. This protein can bind heparin. (99 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (240 aa) |
| | CXCL10 | C-X-C motif chemokine. (104 aa) |
| | XK | XK-related protein. (444 aa) |
| | PROKR2 | Prokineticin receptor 2; Belongs to the G-protein coupled receptor 1 family. (384 aa) |
| | GNB5 | G protein subunit beta 5. (420 aa) |
| | GPR68 | G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (370 aa) |
| | HTR2C | 5-hydroxytryptamine receptor 2C. (457 aa) |
| | AGTR1 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. (359 aa) |
| | CCL20 | C-C motif chemokine. (153 aa) |
| | AGT | Angiotensinogen; Belongs to the serpin family. (482 aa) |
| | LOC100516420 | Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (674 aa) |
| | LPAR4 | Lysophosphatidic acid receptor 4; Belongs to the G-protein coupled receptor 1 family. (408 aa) |
| | F2RL3 | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (382 aa) |
| | CXCR3 | C-X-C chemokine receptor type 3 isoform 1; Belongs to the G-protein coupled receptor 1 family. (361 aa) |
| | ADGRE5 | Adhesion G protein-coupled receptor E5; Belongs to the G-protein coupled receptor 2 family. (828 aa) |
| | P2RY10 | P2Y receptor family member 10. (328 aa) |
| | GRM5 | Glutamate metabotropic receptor 5. (1212 aa) |
| | C5AR1 | C5a anaphylatoxin chemotactic receptor 1; Belongs to the G-protein coupled receptor 1 family. (351 aa) |
| | PTGER2 | Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (359 aa) |
| | OPN5 | Opsin 5; Belongs to the G-protein coupled receptor 1 family. (378 aa) |
| | GALR2 | Galanin receptor type 2; Belongs to the G-protein coupled receptor 1 family. (343 aa) |
| | PTGIR | Prostaglandin I2 receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa) |
| | GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (360 aa) |
| | ECE2 | Uncharacterized protein. (1628 aa) |
| | XCR1 | Chemokine XC receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (333 aa) |
| | SUCNR1 | Succinate receptor 1; Belongs to the G-protein coupled receptor 1 family. (318 aa) |
| | GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa) |
| | RXFP2 | Relaxin family peptide receptor 2. (737 aa) |
| | PTGER4 | Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (489 aa) |
| | CCR2 | C-C chemokine receptor type 2 isoform B; Belongs to the G-protein coupled receptor 1 family. (373 aa) |
| | CCR8 | C-C motif chemokine receptor 8; Belongs to the G-protein coupled receptor 1 family. (379 aa) |
| | GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (248 aa) |
| | PROK2 | Prokineticin 2. (129 aa) |
| | MLNR | Motilin receptor; Belongs to the G-protein coupled receptor 1 family. (406 aa) |
| | P2RY11 | PPAN-P2RY11 protein isoform 1; Belongs to the G-protein coupled receptor 1 family. (377 aa) |
| | CCKAR | Cholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa) |
