(20 nodes) RHO GTPases Activate NADPH Oxidases network (Sus scrofa)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	PRKCZ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (629 aa)
	S100A9	EF-hand domain-containing protein; Belongs to the S-100 family. (222 aa)
	S100A8	Protein S100; Belongs to the S-100 family. (89 aa)
	NOX1	NADPH oxidase 1 isoform 1. (564 aa)
	MAPK11	Mitogen-activated protein kinase. (364 aa)
	NCF2	Neutrophil cytosolic factor 2. (643 aa)
	NOXA1	NADPH oxidase activator 1. (474 aa)
	PRKCD	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (723 aa)
	PIK3R4	Phosphoinositide-3-kinase regulatory subunit 4. (1302 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
	RAC1	Rac family small GTPase 1. (186 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	RAC2	Rac family small GTPase 2. (217 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (568 aa)
	NCF4	Neutrophil cytosolic factor 4. (381 aa)
	NOX3	NADPH oxidase 3. (568 aa)
	NCF1	Uncharacterized protein. (378 aa)
	NOXO1	NADPH oxidase organizer 1. (400 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
	PIN1	Peptidyl-prolyl cis-trans isomerase. (163 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAPK1	MAPK11	ENSSSCP00000073842	ENSSSCP00000031859	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.631
MAPK1	MAPK14	ENSSSCP00000073842	ENSSSCP00000064942	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.946
MAPK1	MAPK3	ENSSSCP00000073842	ENSSSCP00000057520	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.901
MAPK1	NCF1	ENSSSCP00000073842	ENSSSCP00000008248	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.917
MAPK1	NCF2	ENSSSCP00000073842	ENSSSCP00000036068	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Neutrophil cytosolic factor 2.	0.907
MAPK1	NCF4	ENSSSCP00000073842	ENSSSCP00000073420	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Neutrophil cytosolic factor 4.	0.503
MAPK1	PRKCA	ENSSSCP00000073842	ENSSSCP00000018296	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.921
MAPK1	PRKCD	ENSSSCP00000073842	ENSSSCP00000054041	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.921
MAPK1	PRKCZ	ENSSSCP00000073842	ENSSSCP00000027683	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.909
MAPK1	RAC1	ENSSSCP00000073842	ENSSSCP00000062132	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Rac family small GTPase 1.	0.542
MAPK1	RAC2	ENSSSCP00000073842	ENSSSCP00000070230	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Rac family small GTPase 2.	0.923
MAPK11	MAPK1	ENSSSCP00000031859	ENSSSCP00000073842	Mitogen-activated protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.631
MAPK11	MAPK14	ENSSSCP00000031859	ENSSSCP00000064942	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.408
MAPK11	MAPK3	ENSSSCP00000031859	ENSSSCP00000057520	Mitogen-activated protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.610
MAPK11	NCF1	ENSSSCP00000031859	ENSSSCP00000008248	Mitogen-activated protein kinase.	Uncharacterized protein.	0.530
MAPK11	NCF2	ENSSSCP00000031859	ENSSSCP00000036068	Mitogen-activated protein kinase.	Neutrophil cytosolic factor 2.	0.473
MAPK11	NCF4	ENSSSCP00000031859	ENSSSCP00000073420	Mitogen-activated protein kinase.	Neutrophil cytosolic factor 4.	0.483
MAPK11	RAC1	ENSSSCP00000031859	ENSSSCP00000062132	Mitogen-activated protein kinase.	Rac family small GTPase 1.	0.588
MAPK14	MAPK1	ENSSSCP00000064942	ENSSSCP00000073842	Mitogen-activated protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.946
MAPK14	MAPK11	ENSSSCP00000064942	ENSSSCP00000031859	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.408