(18 nodes) Regulation of long-term neuronal synaptic plasticity network (Camelus dromedarius)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SHANK3	SH3 and multiple ankyrin repeat domains protein 3. (1334 aa)
	DRD2	D dopamine receptor. (443 aa)
	NEURL1	E3 ubiquitin-protein ligase NEURL1. (574 aa)
	GRM5	Metabotropic glutamate receptor 5. (1005 aa)
	HRAS	GTPase HRas. (265 aa)
	KCNJ15	ATP-sensitive inward rectifier potassium channel 15. (375 aa)
	NETO1	Neuropilin and tolloid-like protein 1. (533 aa)
	RAB5A	Ras-related protein Rab-5A. (215 aa)
	APP	Amyloid-beta A4 protein. (770 aa)
	SYNGAP1	Ras/Rap GTPase-activating protein SynGAP. (1329 aa)
	SYNPR	Synaptoporin. (285 aa)
	DLG4	Disks large-like protein 4. (767 aa)
	KRAS	GTPase KRas. (189 aa)
	SYP	Synaptophysin. (312 aa)
	NF1	Neurofibromin. (2841 aa)
	EPHB2	Ephrin type-B receptor 2. (963 aa)
	GRIK2	Glutamate receptor ionotropic. (908 aa)
	SYNGR1	Synaptogyrin-1. (315 aa)

Your Current Organism:

Camelus dromedarius

NCBI taxonomy Id: 9838
Other names: Arabian camel, C. dromedarius, camel, dromedaries, dromedary, dromedary camel, one-humped camel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APP	GRM5	ENSCDRP00005000935	ENSCDRP00005013498	Amyloid-beta A4 protein.	Metabotropic glutamate receptor 5.	0.577
APP	SYP	ENSCDRP00005000935	ENSCDRP00005027341	Amyloid-beta A4 protein.	Synaptophysin.	0.604
DLG4	GRIK2	ENSCDRP00005029877	ENSCDRP00005020319	Disks large-like protein 4.	Glutamate receptor ionotropic.	0.708
DLG4	KRAS	ENSCDRP00005029877	ENSCDRP00005029351	Disks large-like protein 4.	GTPase KRas.	0.437
DLG4	SHANK3	ENSCDRP00005029877	ENSCDRP00005005716	Disks large-like protein 4.	SH3 and multiple ankyrin repeat domains protein 3.	0.699
DLG4	SYNGAP1	ENSCDRP00005029877	ENSCDRP00005031868	Disks large-like protein 4.	Ras/Rap GTPase-activating protein SynGAP.	0.567
GRIK2	DLG4	ENSCDRP00005020319	ENSCDRP00005029877	Glutamate receptor ionotropic.	Disks large-like protein 4.	0.708
GRIK2	GRM5	ENSCDRP00005020319	ENSCDRP00005013498	Glutamate receptor ionotropic.	Metabotropic glutamate receptor 5.	0.530
GRIK2	NETO1	ENSCDRP00005020319	ENSCDRP00005017827	Glutamate receptor ionotropic.	Neuropilin and tolloid-like protein 1.	0.412
GRIK2	SYNGAP1	ENSCDRP00005020319	ENSCDRP00005031868	Glutamate receptor ionotropic.	Ras/Rap GTPase-activating protein SynGAP.	0.511
GRM5	APP	ENSCDRP00005013498	ENSCDRP00005000935	Metabotropic glutamate receptor 5.	Amyloid-beta A4 protein.	0.577
GRM5	GRIK2	ENSCDRP00005013498	ENSCDRP00005020319	Metabotropic glutamate receptor 5.	Glutamate receptor ionotropic.	0.530
HRAS	KRAS	ENSCDRP00005010489	ENSCDRP00005029351	GTPase HRas.	GTPase KRas.	0.948
HRAS	NF1	ENSCDRP00005010489	ENSCDRP00005023686	GTPase HRas.	Neurofibromin.	0.982
HRAS	SHANK3	ENSCDRP00005010489	ENSCDRP00005005716	GTPase HRas.	SH3 and multiple ankyrin repeat domains protein 3.	0.463
HRAS	SYNGAP1	ENSCDRP00005010489	ENSCDRP00005031868	GTPase HRas.	Ras/Rap GTPase-activating protein SynGAP.	0.772
KRAS	DLG4	ENSCDRP00005029351	ENSCDRP00005029877	GTPase KRas.	Disks large-like protein 4.	0.437
KRAS	HRAS	ENSCDRP00005029351	ENSCDRP00005010489	GTPase KRas.	GTPase HRas.	0.948
KRAS	NF1	ENSCDRP00005029351	ENSCDRP00005023686	GTPase KRas.	Neurofibromin.	0.999
KRAS	SHANK3	ENSCDRP00005029351	ENSCDRP00005005716	GTPase KRas.	SH3 and multiple ankyrin repeat domains protein 3.	0.463