STRINGSTRING
FCGR1A FCGR1A CLEC4E CLEC4E CLEC1A CLEC1A CLEC5A CLEC5A CLEC6A CLEC6A FCER1G FCER1G CLEC10A CLEC10A CLEC4D CLEC4D CLEC12A CLEC12A ENSBTAP00000059637 ENSBTAP00000059637 ENSBTAP00000063132 ENSBTAP00000063132 CLEC4A CLEC4A LILRA4 LILRA4 FCGR3A FCGR3A FCGR2A FCGR2A SYK SYK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FCGR1AUncharacterized protein. (349 aa)
CLEC4EC-type lectin domain family 4 member E. (211 aa)
CLEC1AC-type lectin domain family 1 member A. (278 aa)
CLEC5AC-type lectin domain containing 5A. (195 aa)
CLEC6AC-type lectin domain family 6 member A; Binds high-mannose carbohydrates in a Ca(2+)-dependent manner (By similarity). Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17 cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G a [...] (206 aa)
FCER1GHigh affinity immunoglobulin epsilon receptor subunit gamma; Adapter protein containing an immunoreceptor tyrosine-based activation motif (ITAM) that transduces activation signals from various immunoreceptors. As a component of the high-affinity immunoglobulin E (IgE) receptor, mediates allergic inflammatory signaling in mast cells. As a constitutive component of interleukin-3 receptor complex, selectively mediates interleukin 4/IL4 production by basophils priming T-cells toward effector T-helper 2 subset. Associates with pattern recognition receptors CLEC4D and CLEC4E to form a functi [...] (85 aa)
CLEC10AC-type lectin domain containing 10A. (308 aa)
CLEC4DC-type lectin domain family 4 member D. (213 aa)
CLEC12AC-type lectin domain family 12 member A. (286 aa)
ENSBTAP00000059637Ig-like domain-containing protein. (221 aa)
ENSBTAP00000063132Uncharacterized protein. (308 aa)
CLEC4AC-type lectin domain family 4 member A. (237 aa)
LILRA4Ig-like domain-containing protein. (220 aa)
FCGR3ALow affinity immunoglobulin gamma Fc region receptor III; Is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Also mediates antibody-dependent cellular toxicity (By similarity). (257 aa)
FCGR2AIg-like domain-containing protein. (335 aa)
SYKTyrosine-protein kinase. (628 aa)
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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