STRINGSTRING
GNRH1 GNRH1 GNRHR GNRHR NPFF NPFF QRFPR QRFPR NPFFR2 NPFFR2 NPFFR1 NPFFR1 TACR3 TACR3 QRFP QRFP NPVF NPVF KISS1 KISS1 TAC3 TAC3 UTS2B UTS2B KISS1R KISS1R UTS2 UTS2 ENSBTAP00000066030 ENSBTAP00000066030
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (92 aa)
GNRHRGonadotropin-releasing hormone receptor; Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G- proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. (328 aa)
NPFFPro-FMRFamide-related neuropeptide FF; Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. The neuropeptide FF potentiates and sensitizes ASIC3 cation channel; Belongs to the FARP (FMRFamide related peptide) family. (115 aa)
QRFPRPyroglutamylated RFamide peptide receptor; Belongs to the G-protein coupled receptor 1 family. (431 aa)
NPFFR2Neuropeptide FF receptor 2; Belongs to the G-protein coupled receptor 1 family. (436 aa)
NPFFR1Neuropeptide FF receptor 1; Belongs to the G-protein coupled receptor 1 family. (435 aa)
TACR3Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (463 aa)
QRFPOrexigenic neuropeptide QRFP; Stimulates feeding behavior, metabolic rate and locomotor activity and increases blood pressure. May have orexigenic activity. May promote aldosterone secretion by the adrenal gland (By similarity). Belongs to the RFamide neuropeptide family. (134 aa)
NPVFPro-FMRFamide-related neuropeptide VF; Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion. Neuropeptide NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory activity. Neuropeptide NPVF blocks morphine-induced analgesia (By similarity). (196 aa)
KISS1KiSS-1 metastasis suppressor. (135 aa)
TAC3Neurokinin-B; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Is a critical central regulator of gonadal function (By similarity); Belongs to the tachykinin family. (126 aa)
UTS2BUrotensin 2B. (123 aa)
KISS1RKISS1 receptor. (401 aa)
UTS2Uncharacterized protein. (122 aa)
ENSBTAP00000066030Uncharacterized protein. (127 aa)
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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