(15 nodes) uDENN domain network (Bos taurus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MADD	MAP kinase activating death domain. (1646 aa)
	DENND2A	DENN domain containing 2A. (1022 aa)
	DENND1B	DENN domain containing 1B. (760 aa)
	SBF2	SET binding factor 2. (1906 aa)
	DENND5A	DENN domain containing 5A. (1290 aa)
	DENND2C	DENN domain containing 2C. (936 aa)
	DENND1A	DENN domain containing 1A. (1049 aa)
	SBF1	SET binding factor 1. (1889 aa)
	DENND4C	DENN domain containing 4C. (1964 aa)
	DENND4B	DENN domain containing 4B. (1501 aa)
	DENND1C	DENN domain containing 1C. (798 aa)
	DENND2B	Suppression of tumorigenicity 5. (1153 aa)
	DENND4A	DENN domain containing 4A. (1906 aa)
	DENND2D	DENN domain containing 2D. (478 aa)
	DENND5B	DENN domain containing 5B. (1274 aa)

Your Current Organism:

Bos taurus

NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DENND1A	DENND1B	ENSBTAP00000069607	ENSBTAP00000049155	DENN domain containing 1A.	DENN domain containing 1B.	0.475
DENND1A	DENND1C	ENSBTAP00000069607	ENSBTAP00000042504	DENN domain containing 1A.	DENN domain containing 1C.	0.518
DENND1A	DENND4A	ENSBTAP00000069607	ENSBTAP00000022733	DENN domain containing 1A.	DENN domain containing 4A.	0.559
DENND1A	DENND4B	ENSBTAP00000069607	ENSBTAP00000033928	DENN domain containing 1A.	DENN domain containing 4B.	0.610
DENND1A	DENND4C	ENSBTAP00000069607	ENSBTAP00000068643	DENN domain containing 1A.	DENN domain containing 4C.	0.599
DENND1A	DENND5A	ENSBTAP00000069607	ENSBTAP00000074326	DENN domain containing 1A.	DENN domain containing 5A.	0.560
DENND1A	DENND5B	ENSBTAP00000069607	ENSBTAP00000027075	DENN domain containing 1A.	DENN domain containing 5B.	0.552
DENND1A	MADD	ENSBTAP00000069607	ENSBTAP00000028927	DENN domain containing 1A.	MAP kinase activating death domain.	0.441
DENND1B	DENND1A	ENSBTAP00000049155	ENSBTAP00000069607	DENN domain containing 1B.	DENN domain containing 1A.	0.475
DENND1B	DENND1C	ENSBTAP00000049155	ENSBTAP00000042504	DENN domain containing 1B.	DENN domain containing 1C.	0.489
DENND1B	DENND2A	ENSBTAP00000049155	ENSBTAP00000033540	DENN domain containing 1B.	DENN domain containing 2A.	0.532
DENND1B	DENND4B	ENSBTAP00000049155	ENSBTAP00000033928	DENN domain containing 1B.	DENN domain containing 4B.	0.465
DENND1C	DENND1A	ENSBTAP00000042504	ENSBTAP00000069607	DENN domain containing 1C.	DENN domain containing 1A.	0.518
DENND1C	DENND1B	ENSBTAP00000042504	ENSBTAP00000049155	DENN domain containing 1C.	DENN domain containing 1B.	0.489
DENND1C	DENND4A	ENSBTAP00000042504	ENSBTAP00000022733	DENN domain containing 1C.	DENN domain containing 4A.	0.583
DENND1C	DENND4B	ENSBTAP00000042504	ENSBTAP00000033928	DENN domain containing 1C.	DENN domain containing 4B.	0.685
DENND1C	DENND4C	ENSBTAP00000042504	ENSBTAP00000068643	DENN domain containing 1C.	DENN domain containing 4C.	0.610
DENND1C	DENND5A	ENSBTAP00000042504	ENSBTAP00000074326	DENN domain containing 1C.	DENN domain containing 5A.	0.588
DENND1C	DENND5B	ENSBTAP00000042504	ENSBTAP00000027075	DENN domain containing 1C.	DENN domain containing 5B.	0.673
DENND2A	DENND1B	ENSBTAP00000033540	ENSBTAP00000049155	DENN domain containing 2A.	DENN domain containing 1B.	0.532

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