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CALM-2 CALM-2 CALB2 CALB2 RELN RELN ZNF18 ZNF18 CXCL14 CXCL14 SLC1A7 SLC1A7 SLC1A6 SLC1A6 CALML5 CALML5 CALM3 CALM3 CALB1 CALB1 ALB ALB PVALB PVALB CALML4 CALML4 CD44 CD44 CALM CALM PXDN PXDN UBE3B UBE3B SLC1A2 SLC1A2 MBP MBP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CALM-2Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). (149 aa)
CALB2Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons. (271 aa)
RELNReelin; Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity); Belongs to the reel [...] (3460 aa)
ZNF18Zinc finger protein 18. (550 aa)
CXCL14Chemokine (C-X-C motif) ligand 14. (99 aa)
SLC1A7Amino acid transporter. (560 aa)
SLC1A6Amino acid transporter. (564 aa)
CALML5Calmodulin like 5. (148 aa)
CALM3Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
CALB1Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. (261 aa)
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The sh [...] (607 aa)
PVALBParvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity). (110 aa)
CALML4Calmodulin-like protein 4; Belongs to the calmodulin family. (196 aa)
CD44CD44 antigen. (703 aa)
CALMCalmodulin; Belongs to the calmodulin family. (149 aa)
PXDNPeroxidasin. (1429 aa)
UBE3BUbiquitin protein ligase E3B. (1068 aa)
SLC1A2Amino acid transporter. (595 aa)
MBPMyelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity). (434 aa)
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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