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| | MFNG | Beta-1,3-N-acetylglucosaminyltransferase. (320 aa) |
| | LOC108636623 | Uncharacterized protein. (195 aa) |
| | CEBPG | CCAAT enhancer binding protein gamma. (149 aa) |
| | LOC108634604 | Uncharacterized protein. (195 aa) |
| | LOC108636544 | Uncharacterized protein. (186 aa) |
| | UNG | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (311 aa) |
| | IFNE | Interferon epsilon. (193 aa) |
| | DCAF1 | DDB1 and CUL4 associated factor 1. (1507 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (504 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa) |
| | EXOSC6 | Exosome component 6. (272 aa) |
| | IL2RG | Fibronectin type-III domain-containing protein. (378 aa) |
| | FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (992 aa) |
| | LOC102179943 | Uncharacterized protein. (189 aa) |
| | LOC108636616 | Uncharacterized protein. (195 aa) |
| | GPS2 | G protein pathway suppressor 2. (327 aa) |
| | TNFSF13B | Tumor necrosis factor superfamily member 13b; Belongs to the tumor necrosis factor family. (280 aa) |
| | LRRC8A | Leucine rich repeat containing 8 VRAC subunit A. (810 aa) |
| | LOC108633243 | Uncharacterized protein. (186 aa) |
| | LOC102180392 | Uncharacterized protein. (195 aa) |
| | LOC108636634 | Uncharacterized protein. (186 aa) |
| | LOC108635529 | Uncharacterized protein. (189 aa) |
| | LOC108636617 | Uncharacterized protein. (195 aa) |
| | LOC108635164 | AIG1-type G domain-containing protein. (314 aa) |
| | SWAP70 | Switching B cell complex subunit SWAP70. (585 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (589 aa) |
| | LIG4 | DNA ligase. (911 aa) |
| | LOC108634973 | Uncharacterized protein. (195 aa) |
| | CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa) |
| | ENSCHIP00000000047 | RING-type domain-containing protein. (101 aa) |
| | IRF8 | Interferon regulatory factor 8. (426 aa) |
| | LYL1 | LYL1 basic helix-loop-helix family member. (281 aa) |
| | ADA | Adenosine deaminase. (400 aa) |
| | ENSCHIP00000033427 | Uncharacterized protein. (262 aa) |
| | CTPS1 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (591 aa) |
| | TXLNA | Taxilin alpha. (561 aa) |
| | BCL6 | BCL6 transcription repressor. (706 aa) |
| | ENSCHIP00000032473 | Uncharacterized protein. (189 aa) |
| | ENSCHIP00000032320 | Prohibitin. (189 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | KIAA1841 | KIAA1841. (704 aa) |
| | STAT6 | Signal transducer and activator of transcription. (841 aa) |
| | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (294 aa) |
| | ENSCHIP00000031025 | Uncharacterized protein. (171 aa) |
| | POU2F2 | POU domain protein. (479 aa) |
| | CCR6 | C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | SHB | SH2 domain-containing protein. (507 aa) |
| | LEF1 | HMG box domain-containing protein. (430 aa) |
| | YY1AP1 | Uncharacterized protein. (667 aa) |
| | ENSCHIP00000030196 | Uncharacterized protein. (144 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (382 aa) |
| | DOCK11 | Dedicator of cytokinesis 11; Belongs to the DOCK family. (2087 aa) |
| | SP3 | Sp3 transcription factor. (778 aa) |
| | CD40 | CD40 molecule. (280 aa) |
| | GIMAP1 | AIG1-type G domain-containing protein. (302 aa) |
| | LOC102179668 | Uncharacterized protein. (191 aa) |
| | LAX1 | Uncharacterized protein. (381 aa) |
| | CD19 | CD19 molecule. (561 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (821 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (573 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (157 aa) |
| | LFNG | Beta-1,3-N-acetylglucosaminyltransferase. (380 aa) |
| | EPHB2 | EPH receptor B2. (1016 aa) |
| | ZBTB7A | Zinc finger and BTB domain containing 7A. (602 aa) |
| | NOTCH2 | Notch receptor 2. (2471 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1067 aa) |
| | CD22 | CD22 molecule. (843 aa) |
| | KIT | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (974 aa) |
| | CMTM7 | CKLF like MARVEL transmembrane domain containing 7. (174 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (829 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (946 aa) |
| | ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (339 aa) |
| | STAT5B | Signal transducer and activator of transcription. (808 aa) |
| | GON4L | Myb-like domain-containing protein. (2211 aa) |
| | ABL1 | Tyrosine-protein kinase. (1151 aa) |
| | BTK | Tyrosine-protein kinase. (658 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | FNIP1 | Folliculin interacting protein 1. (1162 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1154 aa) |
| | IL7R | Interleukin 7 receptor. (459 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa) |
| | CXCR5 | C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (374 aa) |
| | SASH3 | SAM and SH3 domain containing 3. (380 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (644 aa) |
| | POU2AF1 | POU class 2 homeobox associating factor 1. (263 aa) |
| | ENSCHIP00000021876 | Uncharacterized protein. (179 aa) |
| | SPI1 | Spi-1 proto-oncogene. (270 aa) |
| | TRAF3IP2 | TRAF3 interacting protein 2. (572 aa) |
| | ENSCHIP00000021158 | Uncharacterized protein. (182 aa) |
| | LOC108635503 | Uncharacterized protein. (195 aa) |
| | ITFG2 | Integrin alpha FG-GAP repeat containing 2. (444 aa) |
| | LOC108635454 | Uncharacterized protein. (195 aa) |
| | LOC108635455 | Uncharacterized protein. (195 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (135 aa) |
| | LOC108633160 | Uncharacterized protein. (189 aa) |
| | FCRL1 | Uncharacterized protein. (303 aa) |
| | TSHR | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (817 aa) |
| | TLR4 | TIR domain-containing protein; Belongs to the Toll-like receptor family. (841 aa) |
| | EXOSC3 | Exosome component 3. (275 aa) |
| | BANK1 | B cell scaffold protein with ankyrin repeats 1. (771 aa) |
| | ONECUT1 | One cut domain family member. (464 aa) |
| | ENSCHIP00000019035 | Uncharacterized protein. (191 aa) |
| | LOC106503900 | AIG1-type G domain-containing protein. (294 aa) |
| | EP300 | E1A binding protein p300. (2411 aa) |
| | NKX2-3 | NK2 homeobox 3. (367 aa) |
| | HMCN2 | Hemicentin 2. (4946 aa) |
| | LOC102178162 | AIG1-type G domain-containing protein. (302 aa) |
| | RABL3 | RAB, member of RAS oncogene family like 3. (236 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa) |
| | CLCF1 | Cardiotrophin like cytokine factor 1. (220 aa) |
| | PHB2 | Prohibitin. (289 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | CD79B | CD79b molecule. (221 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1894 aa) |
| | MALT1 | MALT1 paracaspase. (830 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3058 aa) |
| | IFNK | Interferon kappa. (205 aa) |
| | BCL2 | BH4_2 domain-containing protein. (229 aa) |
| | MEF2C | MADS-box domain-containing protein. (441 aa) |
| | BCL3 | BCL3 transcription coactivator. (454 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa) |
| | TPD52 | Uncharacterized protein. (238 aa) |
| | ENSCHIP00000015031 | Uncharacterized protein. (173 aa) |
| | DCLRE1C | DNA cross-link repair 1C. (710 aa) |
| | DEF6 | DEF6 guanine nucleotide exchange factor. (632 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa) |
| | NHEJ1 | Non-homologous end joining factor 1. (299 aa) |
| | LGALS1 | Galectin-1; Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Has hemaglutinating activity towards human erythrocytes. (136 aa) |
| | ENSCHIP00000012937 | Uncharacterized protein. (188 aa) |
| | MS4A1 | Membrane spanning 4-domains A1. (297 aa) |
| | IKZF3 | IKAROS family zinc finger 3. (509 aa) |
| | FOXP3 | Forkhead box P3. (463 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (417 aa) |
| | CD79A | CD79a molecule. (223 aa) |
| | YY1 | YY1 transcription factor. (415 aa) |
| | ENSCHIP00000011351 | Uncharacterized protein. (171 aa) |
| | ENSCHIP00000011123 | Uncharacterized protein. (190 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) |
| | IL7 | Interleukin 7. (181 aa) |
| | LOC102181595 | Uncharacterized protein. (186 aa) |
| | EXO1 | Exonuclease 1. (835 aa) |
| | GPR183 | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (356 aa) |
| | LOC108636620 | Uncharacterized protein. (195 aa) |
| | PHB | Prohibitin. (272 aa) |
| | AICDA | Activation induced cytidine deaminase. (199 aa) |
| | CDH17 | Cadherin 17. (832 aa) |
| | LOC108636632 | Uncharacterized protein. (186 aa) |
| | SYK | Spleen associated tyrosine kinase. (636 aa) |
| | CD180 | CD180 molecule. (661 aa) |
| | LOC102189208 | Uncharacterized protein. (168 aa) |
| | SKAP2 | Src kinase associated phosphoprotein 2. (358 aa) |
| | IRF2BP2 | Interferon regulatory factor 2 binding protein 2. (588 aa) |
| | ENSCHIP00000007820 | Uncharacterized protein. (173 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (754 aa) |
| | LOC102180761 | Uncharacterized protein. (189 aa) |
| | ADGRG3 | Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family. (547 aa) |
| | GAPT | GRB2 binding adaptor protein, transmembrane. (158 aa) |
| | LOC102181867 | Uncharacterized protein. (186 aa) |
| | LOC108636626 | Uncharacterized protein. (195 aa) |
| | ENSCHIP00000006450 | Uncharacterized protein. (333 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (773 aa) |
| | PLCL2 | Phosphoinositide phospholipase C. (1118 aa) |
| | LOC108636629 | Uncharacterized protein. (186 aa) |
| | LOC108636627 | Uncharacterized protein. (189 aa) |
| | LOC108635000 | Uncharacterized protein. (195 aa) |
| | LOC108636628 | Uncharacterized protein. (195 aa) |
| | ENSCHIP00000005590 | AIG1-type G domain-containing protein. (278 aa) |
| | ENSCHIP00000005465 | Uncharacterized protein. (168 aa) |
| | LOC102174842 | Uncharacterized protein. (189 aa) |
| | BATF | Basic leucine zipper ATF-like transcription factor. (125 aa) |
| | RAG2 | Recombination activating 2. (527 aa) |
| | IFNA | Uncharacterized protein. (189 aa) |
