STRINGSTRING
ESRP2 ESRP2 NKX2-1 NKX2-1 SHH SHH FOXA1 FOXA1 SOX9 SOX9 BMP4 BMP4 FOXF1 FOXF1 CELSR1 CELSR1 YAP1 YAP1 RDH10 RDH10 DAG1 DAG1 TBX2 TBX2 FGF10 FGF10 CTSZ CTSZ EXT1 EXT1 SPRY2 SPRY2 HOXA5 HOXA5 HHIP HHIP DLG5 DLG5 CTNNB1 CTNNB1 CTSH CTSH KRAS KRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ESRP2Epithelial splicing regulatory protein 2. (717 aa)
NKX2-1NK2 homeobox 1. (370 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
FOXA1Forkhead box A1. (468 aa)
SOX9SRY-box transcription factor 9. (525 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
FOXF1Forkhead box F1. (391 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2710 aa)
YAP1Yes associated protein 1. (503 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
DAG1Dystroglycan 1. (895 aa)
TBX2T-box transcription factor 2. (771 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (304 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (446 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
HOXA5Homeobox A5. (270 aa)
HHIPHedgehog interacting protein. (701 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1946 aa)
CTNNB1Catenin beta 1. (781 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (335 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
Your Current Organism:
Capra hircus
NCBI taxonomy Id: 9925
Other names: African dwarf goat, African dwarf goats, C. hircus, Capra aegagrus hircus, domestic goat, goat, goats
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