STRINGSTRING
ATRN ATRN SEMA6D SEMA6D SEMA6C SEMA6C ITGB5 ITGB5 SEMA5B SEMA5B PLXNB2 PLXNB2 ITGB1 ITGB1 SEMA3C SEMA3C ITGB7 ITGB7 SEMA4G SEMA4G ATRNL1 ATRNL1 PLXNC1 PLXNC1 SEMA3E SEMA3E SEMA3A SEMA3A SEMA3D SEMA3D SEMA5A SEMA5A SEMA4C SEMA4C PLXNA2 PLXNA2 SEMA4F SEMA4F ITGB2 ITGB2 SEMA4B SEMA4B ITGB3 ITGB3 MST1R MST1R PLXNB2-2 PLXNB2-2 SEMA3F SEMA3F ITGB8 ITGB8 SEMA3B SEMA3B MEGF8 MEGF8 SEMA4D SEMA4D PLXNA1 PLXNA1 ITGB6 ITGB6 PLXNB3 PLXNB3 PLXNA4 PLXNA4 SEMA4A SEMA4A SEMA3G SEMA3G PLXNA3 PLXNA3 SEMA7A SEMA7A MET MET PLXNB1 PLXNB1 PLXDC2 PLXDC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATRNAttractin. (1293 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1073 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (936 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (802 aa)
SEMA5BSemaphorin 5B. (1095 aa)
PLXNB2Plexin B2. (1727 aa)
ITGB1Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (798 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (798 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (677 aa)
ATRNL1Attractin like 1. (1218 aa)
PLXNC1Plexin C1. (1401 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (822 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (777 aa)
SEMA5ASemaphorin 5A. (1086 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (722 aa)
PLXNA2Plexin A2. (1886 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (771 aa)
ITGB2Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...] (750 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (796 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (778 aa)
MST1RMacrophage stimulating 1 receptor. (1376 aa)
PLXNB2-2PSI domain-containing protein. (84 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (811 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (743 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (746 aa)
MEGF8Multiple EGF like domains 8. (2733 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (864 aa)
PLXNA1Plexin A1. (1574 aa)
ITGB6Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R- G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity). (787 aa)
PLXNB3Plexin B3. (1813 aa)
PLXNA4Plexin A4. (1883 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (762 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (739 aa)
PLXNA3Plexin A3. (1877 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (614 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1384 aa)
PLXNB1Plexin B1. (1989 aa)
PLXDC2Plexin domain containing 2. (529 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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