STRINGSTRING
ITGB3 ITGB3 ITGB2 ITGB2 ITGA9 ITGA9 ITGA5 ITGA5 ITGA7 ITGA7 ITGB8 ITGB8 ITGAD ITGAD ITGAX ITGAX ITGAM ITGAM ITGA8 ITGA8 ITGA1 ITGA1 ITGA2 ITGA2 ITGB6 ITGB6 ITGAL ITGAL ITGA3 ITGA3 ITGAV ITGAV ITGB7 ITGB7 ITGA4 ITGA4 ITGAE ITGAE W5NX55_SHEEP W5NX55_SHEEP ITGA6 ITGA6 ITGB1 ITGB1 ITGA11 ITGA11 ITGB5 ITGB5 ITGA10 ITGA10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGB3Integrin beta; Belongs to the integrin beta chain family. (778 aa)
ITGB2Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...] (750 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1035 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1078 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1187 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (743 aa)
ITGADVWFA domain-containing protein; Belongs to the integrin alpha chain family. (1160 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1161 aa)
ITGAMVWFA domain-containing protein; Belongs to the integrin alpha chain family. (1149 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1064 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1166 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1171 aa)
ITGB6Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R- G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity). (787 aa)
ITGALVWFA domain-containing protein; Belongs to the integrin alpha chain family. (1164 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1039 aa)
ITGAVIntegrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1051 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (798 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1034 aa)
ITGAEIntegrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (725 aa)
W5NX55_SHEEPIntegrin_alpha2 domain-containing protein. (100 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1069 aa)
ITGB1Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (798 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1184 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (802 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1167 aa)
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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