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| | RAC1 | Rac family small GTPase 1. (199 aa) |
| | MSN | FERM domain-containing protein. (577 aa) |
| | ACTR3B | Uncharacterized protein; Belongs to the actin family. (418 aa) |
| | CLDN23 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (298 aa) |
| | MYL9 | Myosin light chain 9. (172 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (656 aa) |
| | GATA4 | GATA binding protein 4. (444 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (484 aa) |
| | ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (830 aa) |
| | CGNL1 | Cingulin like 1. (1299 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | ACTR3 | Uncharacterized protein; Belongs to the actin family. (418 aa) |
| | AMOT | Angiomotin. (1091 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (537 aa) |
| | OCLN | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (521 aa) |
| | NF2 | Neurofibromin 2. (626 aa) |
| | SYMPK | Symplekin. (990 aa) |
| | CLDN11 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa) |
| | MARVELD2 | MARVEL domain containing 2. (607 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (543 aa) |
| | G1SRP4_RABIT | Uncharacterized protein. (417 aa) |
| | NEDD4 | NEDD4 E3 ubiquitin protein ligase. (1315 aa) |
| | CLDN7 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | HSPA4 | Heat shock protein family A (Hsp70) member 4. (837 aa) |
| | CLDN8 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa) |
| | PARD6A | Par-6 family cell polarity regulator alpha. (346 aa) |
| | SYNPO | Synaptopodin. (1128 aa) |
| | CLDN10 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (231 aa) |
| | RAPGEF2 | Rap guanine nucleotide exchange factor 2. (1659 aa) |
| | RAB8B | RAB8B, member RAS oncogene family. (268 aa) |
| | CLDN15 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (227 aa) |
| | DLG1 | Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa) |
| | RAP2C | RAP2C, member of RAS oncogene family. (183 aa) |
| | CLDN4 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (467 aa) |
| | CLDN1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | CLDN16 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (292 aa) |
| | CLDN20 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa) |
| | HCLS1 | Hematopoietic cell-specific Lyn substrate 1. (487 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (392 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2141 aa) |
| | G1T5W0_RABIT | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (367 aa) |
| | RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (466 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (744 aa) |
| | PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa) |
| | MYL12A | Myosin light chain 12A. (172 aa) |
| | WAS | WASP actin nucleation promoting factor. (527 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1316 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). (309 aa) |
| | PARD6B | Par-6 family cell polarity regulator beta. (371 aa) |
| | EPB41L4B | Erythrocyte membrane protein band 4.1 like 4B. (811 aa) |
| | TUBA3E | THAP-type domain-containing protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (780 aa) |
| | TIAM1 | T cell lymphoma invasion and metastasis 1. (1592 aa) |
| | BVES | Blood vessel epicardial substance. (361 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (542 aa) |
| | DLG3 | Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (867 aa) |
| | CLDN6 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa) |
| | TUBA8 | Tubulin alpha 8; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (743 aa) |
| | LOC100356250 | Uncharacterized protein. (292 aa) |
| | LOC100346856 | Uncharacterized protein. (316 aa) |
| | CLDN17 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (223 aa) |
| | CLDN14 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (236 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (435 aa) |
| | LOC100357567 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | TUBA4A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) |
| | CLDN2 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (306 aa) |
| | CLDN25 | Claudin 25. (229 aa) |
| | LOC100348967 | Uncharacterized protein. (316 aa) |
| | ACTN4 | Actinin alpha 4. (653 aa) |
| | PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (521 aa) |
| | MPP4 | Membrane palmitoylated protein 4; Belongs to the MAGUK family. (636 aa) |
| | TJAP1 | Tight junction associated protein 1. (559 aa) |
| | LLGL2 | LLGL scribble cell polarity complex component 2. (1009 aa) |
| | LOC108175401 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | CLDN22 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | MYH11 | Myosin-11; Muscle contraction. (1944 aa) |
| | CLDN19 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (313 aa) |
| | CGN | Cingulin (Predicted). (1204 aa) |
| | JAM2 | Junctional adhesion molecule 2. (297 aa) |
| | CDC42-2 | Uncharacterized protein. (222 aa) |
| | MYL2 | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...] (232 aa) |
| | DLG2 | Discs large MAGUK scaffold protein 2. (1011 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (509 aa) |
| | ARHGEF18 | Uncharacterized protein. (555 aa) |
| | VASP | WH1 domain-containing protein. (147 aa) |
| | PRKAG1 | Uncharacterized protein. (378 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (439 aa) |
| | ENSOCUP00000031289 | Uncharacterized protein. (151 aa) |
| | TUBA1B | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | CTTN | Cortactin. (653 aa) |
| | RAPGEF6 | Uncharacterized protein. (1531 aa) |
| | TUBAL3 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (466 aa) |
| | AMOTL1 | Angiomotin like 1. (1013 aa) |
| | CLDN34 | Uncharacterized protein. (223 aa) |
| | MPDZ | Multiple PDZ domain crumbs cell polarity complex component. (2107 aa) |
| | YBX3 | Y-box binding protein 3. (453 aa) |
| | ROCK1 | Rho-associated protein kinase 1; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity (By similarity). Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, TPPP, PFN1 and PPP1R12A (By similarity). Phosphorylates FHOD1 and acts synergistically with it to promote SRC- dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 [...] (1352 aa) |
| | TJP2 | Uncharacterized protein; Belongs to the MAGUK family. (1209 aa) |
| | CFTR | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1481 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (447 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1408 aa) |
| | CD1A | Ig-like domain-containing protein. (353 aa) |
| | ARHGAP17 | Rho GTPase activating protein 17. (878 aa) |
| | RDX | Radixin. (643 aa) |
| | ACTR2 | Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (425 aa) |
| | MYH10 | Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa) |
| | ARHGEF2 | Rho/Rac guanine nucleotide exchange factor 2. (1180 aa) |
| | F11R | F11 receptor. (314 aa) |
| | CD1B | T-cell surface glycoprotein CD1b; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. (352 aa) |
| | NEDD4L | NEDD4 like E3 ubiquitin protein ligase. (1239 aa) |
| | TUBA3D | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) |
| | ACTN1 | Actinin alpha 1. (1038 aa) |
| | EZR | Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). (653 aa) |
| | JUN | BZIP domain-containing protein; Belongs to the bZIP family. (352 aa) |
| | CD1E | Ig-like domain-containing protein. (324 aa) |
| | RAP1A | Uncharacterized protein. (184 aa) |
| | MAGI1 | Membrane associated guanylate kinase, WW and PDZ domain containing 1. (1358 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (714 aa) |
| | JAM3 | Junctional adhesion molecule 3. (405 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) |
| | ACTB | Uncharacterized protein. (357 aa) |
| | LOC100349824 | Uncharacterized protein. (283 aa) |
| | CD1C | Ig-like domain-containing protein. (359 aa) |
| | MPP5 | Membrane palmitoylated protein 5; Belongs to the MAGUK family. (698 aa) |
| | PARD3 | Par-3 family cell polarity regulator. (1340 aa) |
| | RAB13 | Uncharacterized protein. (237 aa) |
