node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MDS_0002 | MDS_1900 | MDS_0002 | MDS_1900 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase. | 0.429 |
MDS_0002 | MDS_2413 | MDS_0002 | MDS_2413 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA ligase. | 0.911 |
MDS_0002 | MDS_2516 | MDS_0002 | MDS_2516 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA ligase. | 0.906 |
MDS_0002 | MDS_3838 | MDS_0002 | MDS_3838 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase II. | 0.986 |
MDS_0002 | ligA | MDS_0002 | MDS_1932 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.429 |
MDS_0002 | polA | MDS_0002 | MDS_0170 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.995 |
MDS_1900 | MDS_0002 | MDS_1900 | MDS_0002 | DNA topoisomerase. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.429 |
MDS_1900 | MDS_2413 | MDS_1900 | MDS_2413 | DNA topoisomerase. | ATP-dependent DNA ligase. | 0.837 |
MDS_1900 | MDS_2515 | MDS_1900 | MDS_2515 | DNA topoisomerase. | RNA procession exonuclease-like protein. | 0.527 |
MDS_1900 | MDS_2516 | MDS_1900 | MDS_2516 | DNA topoisomerase. | ATP-dependent DNA ligase. | 0.708 |
MDS_1900 | MDS_3838 | MDS_1900 | MDS_3838 | DNA topoisomerase. | DNA polymerase II. | 0.566 |
MDS_1900 | polA | MDS_1900 | MDS_0170 | DNA topoisomerase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.491 |
MDS_2413 | MDS_0002 | MDS_2413 | MDS_0002 | ATP-dependent DNA ligase. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.911 |
MDS_2413 | MDS_1900 | MDS_2413 | MDS_1900 | ATP-dependent DNA ligase. | DNA topoisomerase. | 0.837 |
MDS_2413 | MDS_2515 | MDS_2413 | MDS_2515 | ATP-dependent DNA ligase. | RNA procession exonuclease-like protein. | 0.749 |
MDS_2413 | MDS_2516 | MDS_2413 | MDS_2516 | ATP-dependent DNA ligase. | ATP-dependent DNA ligase. | 0.737 |
MDS_2413 | MDS_2517 | MDS_2413 | MDS_2517 | ATP-dependent DNA ligase. | DEAD/DEAH box helicase domain-containing protein. | 0.549 |
MDS_2413 | MDS_2518 | MDS_2413 | MDS_2518 | ATP-dependent DNA ligase. | ICC-like putative phosphoesterase. | 0.566 |
MDS_2413 | MDS_3838 | MDS_2413 | MDS_3838 | ATP-dependent DNA ligase. | DNA polymerase II. | 0.708 |
MDS_2413 | ligA | MDS_2413 | MDS_1932 | ATP-dependent DNA ligase. | NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.493 |