STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
acsacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (653 aa)    
Predicted Functional Partners:
gltA
Type II citrate synthase; Belongs to the citrate synthase family.
  
 0.947
MDS_2639
Methylcitrate synthase; Belongs to the citrate synthase family.
  
 0.947
MDS_2827
DNA binding domain-containing protein.
  
 0.947
MDS_3947
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.944
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 0.943
glcB-2
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 0.943
mmsA
Methylmalonate-semialdehyde dehydrogenase.
  
 0.935
mmsA-2
Methylmalonate-semialdehyde dehydrogenase.
  
 0.935
MDS_2683
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.933
MDS_2936
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.933
Your Current Organism:
Pseudomonas mendocina NK01
NCBI taxonomy Id: 1001585
Other names: P. mendocina NK-01, Pseudomonas mendocina NK-01, Pseudomonas mendocina str. NK-01, Pseudomonas mendocina strain NK-01
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