STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO0549Putative acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (92 aa)    
Predicted Functional Partners:
SCO6560
SC4B5.10c, respiratory chain oxidoreductase, len: 646 aa; C-terminal region is similar to the N-terminal region of many proteins involved in electron transfer e.g. TR:O27592 (EMBL:AE000915) NADP-reducing hydrogenase, subunit C from Methanobacterium thermoautotrophicum (630 aa), fasta scores; opt: 121,4 z-score: 1170.7, E(): 0, (47.1% identity in 397 aa overlap). Contains PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2.
 
 0.989
SCO0547
SCF11.27c, possible acyltransferase, len: 333 aa; similar to TR:CAB52353 (EMBL:AL109747) Streptomyces coelicolor putative multi-domain beta keto-acyl synthase, 2082 aa; fasta scores: opt: 402 z-score: 416.4 E(): 8e-16; 32.5% identity in 329 aa overlap, and to TR:Q55226 (EMBL:L34880) Streptomyces sp. acyltransferase DauA, 338 aa; fasta scores: opt: 326 z-score: 349.0 E(): 4.5e-12; 33.4% identity in 326 aa overlap. Contains Pfam match to entry PF00698 acyl_transf, acyl transferase domain.
  
 0.942
SCO2390
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
 
 0.927
SCO6431
SC1A6.20, probable peptide synthase, len: 1171 aa; similar to many e.g. TR:Q44103 (EMBL:X97860) Amycolatopsis mediterranei aps gene for peptide synthetase (1324 aa), fasta scores; opt: 379 z-score: 1175.7 E(): 0, 32.3% identity in 993 aa overlap. Contains PS00455 Putative AMP-binding domain signature, PS00012 Phosphopantetheine attachment site and Pfam match to entry AMP-binding PF00501, AMP-binding enzymes, score 421.02.
  
 
 0.923
SCO2387
SC4A7.15, fabD, malonyl CoA:acyl carrier protein malonyltransferase, len: 316 aa; identical to previously sequenced TR:P72391 (EMBL:X86475) Streptomyces coelicolor malonyl CoA:acyl carrier protein malonyltransferase, FabD, 316 aa and similar to SW:FABD_ECOLI (EMBL:M87040) Escherichia coli malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39) FabD, 308 aa; fasta scores: opt: 524 z-score: 551.4 E(): 2.5e-23; 36.8% identity in 315 aa overlap. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain.
  
 0.910
SCO1267
2SCG18.14c, probable acyl carrier protein, len: 85 aa; similar to TR:O54150 (EMBL:AL021409) Streptomyces coelicolor acyl carrier protein SC3F7.07c, 81 aa; fasta scores: opt: 175 z-score: 253.1 E(): 1.3e-06; 38.7% identity in 75 aa overlap and to SW:ACP_RHIME (EMBL:AF159244) Rhizobium meliloti acyl carrier protein AcpP, 77 aa; fasta scores: opt: 118 z-score: 177.8 E(): 0.02; 33.3% identity in 66 aa overlap. Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site.
     
  0.900
SCO2389
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
     
  0.900
SCO3249
SCE29.18c, probable acyl carrier protein, len: 81 aa; member of a large family including SW:ACP_HELPY acyl carrier protein from Helicobacter pylori (78 aa) fasta scores; opt: 121, z-score: 179.0, E(): 0.012, (37.5% identity in 64 aa overlap). Contains Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site, score 31.20, E-value 5.3e-07.
     
  0.900
SCO0548
SCF11.28c, fabB2, possible 3-oxoacyl-(acyl-carrier-protein) synthase, len: 428 aa; similar to TR:Q54208 (EMBL:L43074) Streptomyces glaucescens fabB, 423 aa; fasta scores: opt: 1375 z-score: 1459.4 E(): 0; 52.1% identity in 420 aa overlap. Contains Pfam match to entry PF00109 ketoacyl-synt, beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 
 0.861
SCO2597
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
 
 0.851
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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