STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO0650Putative gas vesicle synthesis protein; Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure (By similarity). (170 aa)    
Predicted Functional Partners:
SCO0651
SCF91.11, gvpF2, possible gas vesicle synthesis protein, len: 261 aa. Highly similar to many other gas vesicle synthesis proteins including: Bacillus megaterium TR:O68674(EMBL:AF053765) gas vesicle protein GvpF (255 aa), fasta scores opt: 181 z-score: 209.5 E(): 0.00027 24.2% identity in 211 aa overlap and Streptomyces coelicolor TR:Q9ZC12 (EMBL:AL033505) putative gas vesicle synthesis protein GvpF (257 aa), fasta scores opt: 459 z-score: 515.7 E(): 2.4e-21 38.9% identity in 244 aa overlap.
 
   
 0.983
SCO0656
SCF91.16, gvpL2, possible gas vesicle synthesis protein, len: 280 aa. Weakly similar to Bacillus megaterium TR:O6872 (EMBL:AF053765) gas vesicle protein GvpL (269 aa), fasta scores opt: 172 z-score: 189.1 E(): 0.0037 19.8% identity in 222 aa overlap. Also similar to Streptomyces coelicolor TR:Q9ZC07 (EMBL:AL033505) putative gas vesicle synthesis protein GvpL (259 aa), fasta scores opt: 436 z-score: 462.0 E(): 2.3e-18 37.0% identity in 254 aa overlap. Contains possible N-terminal region signal peptide sequence.
 
   
 0.977
SCO0649
SCF91.09, gvpO2, possible gas vesicle synthesis protein, len: 105 aa. Similar in parts to several other gas vesicle synthesis proteins including: Halobacterium salinarium SW:GVO2_HALSA (EMBL:X64730) gas vesicle synthesis protein protein, chromosomal (111 aa), fasta scores opt: 205 z-score: 272.6 E(): 8.2e-08 39.0% identity in 77 aa overlap and Streptomyces coelicolor TR:Q9ZC14 (EMBL:AL033505) putative gas vesicle synthesis protein GvpO (130 aa), fasta scores opt: 223 z-score: 294.0 E(): 5.3e-09 48.7% identity in 76 aa overlap.
 
   
 0.975
SCO0657
SCF91.17, gvpS2, possible gas vesicle synthesis protein, len: 69 aa. Highly similar to Bacillus megaterium TR:O6869(EMBL:AF053765) gas vesicle protein GvpS (95 aa), fasta scores opt: 143 z-score: 203.5 E(): 0.00059 39.3% identity in 56 aa overlap and Streptomyces coelicolor TR:Q9ZC06 (EMBL:AL033505) putative gas vesicle synthesis protein GvpS (60 aa), fasta scores opt: 214 z-score: 298.0 E(): 3.2e-09 63.5% identity in 52 aa overlap. Contains a possible membrane spanning hydrophobic domain and a Pfam match to entry PF00741 Gas_vesicle, Gas vesicle protein.
 
   
 0.971
SCO0652
SCF91.12, gvpG2, possible gas vesicle synthesis protein, len: 92 aa. Similar to Bacillus megaterium TR:O68673(EMBL:AF053765) gas vesicle protein GvpG (88 aa), fasta scores opt: 108 z-score: 155.4 E(): 0.28 31.7% identity in 63 aa overlap and Streptomyces coelicolor TR:Q9ZC11 (EMBL:AL033505) putative gas vesical synthesis protein GvpG (87 aa), fasta scores opt: 216 z-score: 290.9 E(): 7.9e-09 43.7% identity in 87 aa overlap. Contains a probable coiled-coil from 40 to 67 (28 residues).
 
   
 0.970
SCO0655
Putative gas vesicle synthesis protein; Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. This protein could be important for the shape determination of the gas vesicle (By similarity).
 
   
 0.966
SCO6501
SC1E6.10, gvpF, probable gas vesicle synthesis protein, len: 257 aa; some similarity to GVF2_HALSA GVPF protein, chromosomal (217 aa), fasta scores; opt: 143 z-score: 191.0 E(): 0.0023, 27.1% identity in 247 aa overlap.
 
   
 0.965
SCO0658
SCF91.18, gvpK2, possible gas vesicle synthesis protein, len: 100 aa. Highly similar to many other gas vesicle synthesis proteins including: Halobacterium salinarium SW:GVK2_HALSA(EMBL:X64730) gas vesicle synthesis protein GvpK (119 aa), fasta scores opt: 163 z-score: 224.6 E(): 3.9e-05 43.3% identity in 67 aa overlap and Bacillus megaterium TR:O68670(EMBL:AF053765) gas vesicle protein GvpK (94 aa), fasta scores opt: 302 z-score: 402.9 E(): 4.6e-15 53.3% identity in 92 aa overlap. Also highly similar to Streptomyces coelicolor TR:Q9ZC05 (EMBL:AL033505) putative gas vesicle synthesis pr [...]
 
   
 0.956
SCO6507
SC1E6.16, gvpS, probable gas vesicle synthesis protein, len: 60 aa; similar to parts of several gas vesicle proteins e.g. Bacillus megaterium TR:O68671 (EMBL:AF053765) gas vesicle protein GVPS (95 aa), fasta scores; opt: 163 z-score: 303.6 E(): 1.2e-09, 49.1% identity in 57 aa overlap, and TR:O68669 (EMBL:AF053765) gas vesicle protein GVPJ (100 aa), fasta scores; opt: 130 z-score: 256.8 E(): 5.1e-07, 45.2% identity in 42 aa overlap. Contains Pfam match to entry PF00741 Gas_vesicle, Gas vesicle protein, score 31.70, E-value 1.7e-05.
 
   
 0.955
SCO0653
SCF91.13, unknown, len: 183 aa. Similar to two proteins of unknown function from Streptomyces coelicolor TR:CAB44390(EMBL:AL078610) SCH35.37C (199 aa), fasta scores opt: 378 z-score: 365.6 E(): 5.5e-13 38.3% identity in 196 aa overlap and TR: Q9ZC10(EMBL:AL033505) SC1E6.12 (239 aa), fasta scores opt: 327 z-score: 317.7 E(): 2.6e-10 35.1% identity in 228 aa overlap.
 
     0.939
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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