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SCO0663 protein (Streptomyces coelicolor) - STRING interaction network
"SCO0663" - SCF91.23, possible 2-hydroxyacid-family dehydrogenase, len: 343 aa. Similar in parts to several D-3-phosphoglycerate dehydrogenases e.g. Mycobacterium tuberculosis SW:SERA_MYCTU in Streptomyces coelicolor
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
SCO0663SCF91.23, possible 2-hydroxyacid-family dehydrogenase, len- 343 aa. Similar in parts to several D-3-phosphoglycerate dehydrogenases e.g. Mycobacterium tuberculosis SW-SERA_MYCTU (EMBL-AL021287) (528 aa), fasta scores opt- 450 z-score- 536.4 E()- 1.7e-22 34.1% identity in 261 aa overlap. Also similar to Streptomyces coelicolor TR-CAB55710(EMBL-AL117387) possible dehydrogenase SCF41.07 (339 aa), fasta scores opt- 927 z-score- 1106.0 E()- 0 48.6% identity in 325 aa overlap. Contains a Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenases and a Prosite hit [...] (343 aa)    
Predicted Functional Partners:
SCO0664
SCF91.24, hypothetical protein, len- 631 aa; similar to TR-CAC48915 (EMBL-AL603643) Rhizobium meliloti (Sinorhizobium meliloti) hypothetical protein SMB20536, 617 aa; fasta scores- opt- 524 Z-score- 553.7 E()- 3.3e-23; 30.182% identity in 550 aa overlap (631 aa)
 
          0.937
SCO0661
SCF91.21, possible binding protein dependent transport protein, len- 328 aa. Similar to many membrane transport proteins e.g. Escherichia coli SW-UGPA_ECOLI(EMBL-X13141) SN-glycerol-3-phosphate transport system permease (295 aa), fasta scores opt- 393 z-score- 465.7 E()- 1.5e-18 28.7% identity in 282 aa overlap and Streptomyces coelicolor TR-CAB41203(EMBL-AL049661) binding protein dependent transport protein (327 aa), fasta scores opt- 452 z-score- 533.8 E()- 2.4e-22 28.2% identity in 326 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport [...] (328 aa)
 
          0.883
SCO0662
SCF91.22, possible binding protein dependent transport protein, len- 287 aa. Similar to many membrane transport proteins e.g. Agrobacterium radiobacter SW-LACG_AGRRD(EMBL-X66596) lactose transport system permease (273 aa), fasta scores opt- 439 z-score- 546.1 E()- 4.8e-23 28.5% identity in 267 aa overlap and Bacillus subtilis TR-O05095(EMBL-X89810) integral protein (281 aa), fasta scores opt- 480 z-score- 596.3 E()- 7.7e-26 30.8% identity in 266 aa overlap. Contains a Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component and multip [...] (287 aa)
              0.859
SCO0660
SCF91.20, probable solute-binding lipoprotein, len- 443 aa. Similar to several solute-binding proteins e.g. Agrobacterium radiobacter SW-LACE_AGRRD(EMBL-X66596) lactose-binding protein precursor (422 aa), fasta scores opt- 270 z-score- 303.1 E()- 1.6e-09 23.5% identity in 387 aa overlap and Streptomyces coelicolor TR-P72397(EMBL-Y07706) maltose-binding protein MalE (423 aa), fasta scores opt- 345 z-score- 386.1 E()- 4e-14 25.5% identity in 459 aa overlap. Contains a Pfam match to entry PF01547 SBP_bacterial_1, Bacterial extracellular solute-binding protein. Also contains an appropriate [...] (443 aa)
 
          0.851
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily (363 aa)
   
 
  0.753
SCO0659
SCF91.19, possible DeoR-family transcriptional regulator, len- 368 aa. Similar to many DNA-binding regulatory proteins including- Streptomyces reticuli TR-CAB46346(EMBL-AJ009798) regulator CebR (350 aa), fasta scores opt- 287 z-score- 337.9 E()- 1.9e-11 30.6% identity in 359 aa overlap and Streptomyces lividans SW-REGL_STRLI (EMBL-X98242) transcription regulatory protein RegL (345 aa), fasta scores opt- 276 z-score- 325.3 E()- 9.6e-11 28.9% identity in 353 aa overlap. Contains Pfam matches to entries PF00455 deoR, Bacterial regulatory proteins, deoR family and Pfam match to entry PF005 [...] (368 aa)
 
          0.688
SCO2750
SCC57A.21c, hypothetical protein, len- 287 aa; similar to TR-CAC41509 (EMBL-AL591782) Rhizobium meliloti (Sinorhizobium meliloti) conserved hypothetical protein SMC04130, 274 aa; fasta scores- opt- 796 Z-score- 889.6 E()- 6.4e-42; 47.191% identity in 267 aa overlap (287 aa)
 
        0.550
SCO2752
SCC57A.23c, possible oxidoreductase, len- 378 aa. Weakly similar to several other oxidoreductases e.g. Streptomyces coelicolor TR-O69945 (EMBL-AL023862) oxidoreductase (430 aa), fasta scores opt- 252 z-score- 300.4 E()- 2.4e-09 28.8% identity in 278 aa overlap. Contains a Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase family (378 aa)
 
        0.539
SCO2751
Uncharacterized protein; SCC57A.22c, unknown, len- 388 aa (388 aa)
 
   
  0.531
SCO0665
Putative secreted protein; SCF91.25, possible hypothetical protein, len- 75 aa. Contains a possible N-terminal signal sequence (75 aa)
              0.514
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor, Streptomyces coelicolor A3(2)
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