node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCO0140 | SCO0895 | gene:17757724 | gene:17758478 | SCJ33.04, possible merR-family transcriptional regulator, len: 275 aa. Similar to several e.g. Streptomyces coelicolor TR:CAB56383 (EMBL; AL118515) putative merR family transcriptional regulator SCD17.06C (319 aa), fasta scores opt: 164 z-score: 194.6 E(): 0.0018 28.9% identity in 298 aa overlap and Bacillus subtilis SW:BLTR_BACSU (EMBL; L32599) multidrug-efflux transporter 2 regulator (273 aa), fasta scores opt: 154 z-score: 184.2 E(): 0.0069 21.3% identity in 253 aa overlap. Contains a Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family. Contains a possible h [...] | RNA polymerase principal sigma factor HrdC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.875 |
SCO0140 | SCO1478 | gene:17757724 | gene:17759064 | SCJ33.04, possible merR-family transcriptional regulator, len: 275 aa. Similar to several e.g. Streptomyces coelicolor TR:CAB56383 (EMBL; AL118515) putative merR family transcriptional regulator SCD17.06C (319 aa), fasta scores opt: 164 z-score: 194.6 E(): 0.0018 28.9% identity in 298 aa overlap and Bacillus subtilis SW:BLTR_BACSU (EMBL; L32599) multidrug-efflux transporter 2 regulator (273 aa), fasta scores opt: 154 z-score: 184.2 E(): 0.0069 21.3% identity in 253 aa overlap. Contains a Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family. Contains a possible h [...] | Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.901 |
SCO0140 | SCO4654 | gene:17757724 | gene:17762303 | SCJ33.04, possible merR-family transcriptional regulator, len: 275 aa. Similar to several e.g. Streptomyces coelicolor TR:CAB56383 (EMBL; AL118515) putative merR family transcriptional regulator SCD17.06C (319 aa), fasta scores opt: 164 z-score: 194.6 E(): 0.0018 28.9% identity in 298 aa overlap and Bacillus subtilis SW:BLTR_BACSU (EMBL; L32599) multidrug-efflux transporter 2 regulator (273 aa), fasta scores opt: 154 z-score: 184.2 E(): 0.0069 21.3% identity in 253 aa overlap. Contains a Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family. Contains a possible h [...] | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.918 |
SCO0140 | SCO4655 | gene:17757724 | gene:17762304 | SCJ33.04, possible merR-family transcriptional regulator, len: 275 aa. Similar to several e.g. Streptomyces coelicolor TR:CAB56383 (EMBL; AL118515) putative merR family transcriptional regulator SCD17.06C (319 aa), fasta scores opt: 164 z-score: 194.6 E(): 0.0018 28.9% identity in 298 aa overlap and Bacillus subtilis SW:BLTR_BACSU (EMBL; L32599) multidrug-efflux transporter 2 regulator (273 aa), fasta scores opt: 154 z-score: 184.2 E(): 0.0069 21.3% identity in 253 aa overlap. Contains a Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family. Contains a possible h [...] | DNA-directed RNA polymerase beta' chain (fragment); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.901 |
SCO0140 | SCO4729 | gene:17757724 | gene:17762378 | SCJ33.04, possible merR-family transcriptional regulator, len: 275 aa. Similar to several e.g. Streptomyces coelicolor TR:CAB56383 (EMBL; AL118515) putative merR family transcriptional regulator SCD17.06C (319 aa), fasta scores opt: 164 z-score: 194.6 E(): 0.0018 28.9% identity in 298 aa overlap and Bacillus subtilis SW:BLTR_BACSU (EMBL; L32599) multidrug-efflux transporter 2 regulator (273 aa), fasta scores opt: 154 z-score: 184.2 E(): 0.0069 21.3% identity in 253 aa overlap. Contains a Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family. Contains a possible h [...] | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.902 |
SCO0895 | SCO0140 | gene:17758478 | gene:17757724 | RNA polymerase principal sigma factor HrdC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | SCJ33.04, possible merR-family transcriptional regulator, len: 275 aa. Similar to several e.g. Streptomyces coelicolor TR:CAB56383 (EMBL; AL118515) putative merR family transcriptional regulator SCD17.06C (319 aa), fasta scores opt: 164 z-score: 194.6 E(): 0.0018 28.9% identity in 298 aa overlap and Bacillus subtilis SW:BLTR_BACSU (EMBL; L32599) multidrug-efflux transporter 2 regulator (273 aa), fasta scores opt: 154 z-score: 184.2 E(): 0.0069 21.3% identity in 253 aa overlap. Contains a Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family. Contains a possible h [...] | 0.875 |
SCO0895 | SCO1421 | gene:17758478 | gene:17759007 | RNA polymerase principal sigma factor HrdC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Hypothetical protein SC6D7.18c; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Stimulates transcription from several principal sigma factor HrdB (SigA)-dependent promoters but not from a SigR-dependent promoter. Stimulation occurs in the presence of the transcription initiation inhibitor rifampicin (Rif). | 0.935 |
SCO0895 | SCO1478 | gene:17758478 | gene:17759064 | RNA polymerase principal sigma factor HrdC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.925 |
SCO0895 | SCO4223 | gene:17758478 | gene:17761867 | RNA polymerase principal sigma factor HrdC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 2SCD46.37c, possible AraC-family transcriptional regulator, len: 295aa; similar to many eg. SW:P22539 (SOXS_ECOLI) regulatory protein SoxS from Escherichia coli (106 aa) fasta scores; opt: 186, z-score: 223.7, E(): 5.4e-05, 28.4% identity in 95 aa overlap and TR:P96662 (EMBL:AB001488) probable hth_arac_family of transcriptional regulator from Bacillus subtilis (290 aa) fasta scores; opt: 726, z-score: 825.6, E(): 0, 37.7% identity in 289 aa overlap. Contains Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family and Prosite match to PS00041 Ba [...] | 0.851 |
SCO0895 | SCO4232 | gene:17758478 | gene:17761876 | RNA polymerase principal sigma factor HrdC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | SCD8A.05, probable transcriptional factor regulator, len: 160 aa; similar to TR:O53568 (EMBL:AL022075) Mycobacterium tuberculosis putative transcriptional regulator RV3583c, 162 aa; fasta scores: opt: 878 z-score: 1046.7 E(): 0; 85.0% identity in 160 aa overlap. | 0.898 |
SCO0895 | SCO4443 | gene:17758478 | gene:17762088 | RNA polymerase principal sigma factor HrdC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | SCD6.21c, possible merR-family transcriptional regulator, len: 294 aa; similar to TR:AAF11989 (EMBL:AE002074) Deinococcus radiodurans transcriptional regulator, merR-family DR2448, 280 aa; fasta scores: opt: 465 z-score: 562.4 E(): 7.3e-24; 43.0% identity in 286 aa overlap. Contains Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family and match to Prosite entry PS00552 Bacterial regulatory proteins, merR family signature. | 0.875 |
SCO0895 | SCO4654 | gene:17758478 | gene:17762303 | RNA polymerase principal sigma factor HrdC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.969 |
SCO0895 | SCO4655 | gene:17758478 | gene:17762304 | RNA polymerase principal sigma factor HrdC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA-directed RNA polymerase beta' chain (fragment); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.958 |
SCO0895 | SCO4729 | gene:17758478 | gene:17762378 | RNA polymerase principal sigma factor HrdC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.966 |
SCO0895 | SCO5190 | gene:17758478 | gene:17762839 | RNA polymerase principal sigma factor HrdC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Putative DNA-binding protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. | 0.832 |
SCO1421 | SCO0895 | gene:17759007 | gene:17758478 | Hypothetical protein SC6D7.18c; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Stimulates transcription from several principal sigma factor HrdB (SigA)-dependent promoters but not from a SigR-dependent promoter. Stimulation occurs in the presence of the transcription initiation inhibitor rifampicin (Rif). | RNA polymerase principal sigma factor HrdC; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.935 |
SCO1421 | SCO1478 | gene:17759007 | gene:17759064 | Hypothetical protein SC6D7.18c; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Stimulates transcription from several principal sigma factor HrdB (SigA)-dependent promoters but not from a SigR-dependent promoter. Stimulation occurs in the presence of the transcription initiation inhibitor rifampicin (Rif). | Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.992 |
SCO1421 | SCO4232 | gene:17759007 | gene:17761876 | Hypothetical protein SC6D7.18c; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Stimulates transcription from several principal sigma factor HrdB (SigA)-dependent promoters but not from a SigR-dependent promoter. Stimulation occurs in the presence of the transcription initiation inhibitor rifampicin (Rif). | SCD8A.05, probable transcriptional factor regulator, len: 160 aa; similar to TR:O53568 (EMBL:AL022075) Mycobacterium tuberculosis putative transcriptional regulator RV3583c, 162 aa; fasta scores: opt: 878 z-score: 1046.7 E(): 0; 85.0% identity in 160 aa overlap. | 0.973 |
SCO1421 | SCO4654 | gene:17759007 | gene:17762303 | Hypothetical protein SC6D7.18c; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Stimulates transcription from several principal sigma factor HrdB (SigA)-dependent promoters but not from a SigR-dependent promoter. Stimulation occurs in the presence of the transcription initiation inhibitor rifampicin (Rif). | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.987 |
SCO1421 | SCO4655 | gene:17759007 | gene:17762304 | Hypothetical protein SC6D7.18c; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Stimulates transcription from several principal sigma factor HrdB (SigA)-dependent promoters but not from a SigR-dependent promoter. Stimulation occurs in the presence of the transcription initiation inhibitor rifampicin (Rif). | DNA-directed RNA polymerase beta' chain (fragment); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.985 |