STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO1170Xylulose kinase; Catalyzes the phosphorylation of D-xylulose to D-xylulose 5- phosphate; Belongs to the FGGY kinase family. (481 aa)    
Predicted Functional Partners:
SCO1169
2SCG11.03c, xylA, xylose isomerase, len: 387 aa; identical to SW:XYLA_STRRU (EMBL:M73789) Streptomyces rubiginosus xylose isomerase XylA, 387 aa. Contains Pfam match to entry PF00259 Xylose_isom, Xylose isomerase and matches to Prosite entries PS00172 Xylose isomerase signature 1 and PS00173 Xylose isomerase signature 2.
 
 
 0.999
SCO1171
SCG11A.02, possible xylose repressor, len: 402 aa; similar to SW:XYLR_BACSU (EMBL:M27248) Bacillus subtilis xylose repressor xylR, 384 aa; fasta scores: opt: 612 z-score: 642.4 E(): 2.1e-28; 29.4% identity in 381 aa overlap. Contains match to Pfam entry PF00480 ROK, ROK family and a possible helix-turn-helix motif at residues 43..64 (+3.15 SD).
 
  
 0.924
SCO1464
Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
   
 0.923
SCO2462
SC7A8.01, probable sugar kinase (fragment), len: >434 aa; similar to TR:CAB61582 (EMBL:AL133210) Streptomyces coelicolor xylulose kinase (fragment) XylB, 432 aa; fasta scores: opt: 822 z-score: 871.9 E(): 0; 38.8% identity in 418 aa overlap and to SW:XYLB_STRRU (EMBL:M73789) Streptomyces rubiginosus xylulose kinase (EC 2.7.1.17) XylB, 481 aa; fasta scores: opt: 814 z-score: 862.8 E(): 0; 39.5% identity in 423 aa overlap. Contains Pfam match to entry PF00370 FGGY, FGGY family of carbohydrate kinases and PS00445 FGGY family of carbohydrate kinases signature 2; SCC24.33, probable sugar ki [...]
  
  
 
0.918
SCO3136
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
 
  
 0.744
SCO0355
Conserved hypothetical protein SCF41.14; SCF41.14, unknown, len: 113 aa. Shares a low level of similarity with Bacillus subtilis TR:O05263 (EMBL; Z93938) hypothetical 12.6 KD protein (104 aa), fasta scores opt: 129 z-score: 179.4 E(): 0.012 31.3% identity in 96 aa overlap.
  
  
 0.691
SCO0807
Conserved hypothetical protein SCF43.18c; SCF43.18c, unknown, len: 107 aa. Highly similar to several proteins of unknown function e.g. Escherichia coli SW:YIIL_ECOLI(EMBL:L19201) hypothetical 12.3 KD protein YiiL (104 aa), fasta scores opt: 174 z-score: 248.9 E(): 1.8e-06 31.1% identity in 106 aa overlap and Bacillus subtilis TR:O05263(EMBL:Z93938) hypothetical 12.6 KD protein YulD (104 aa), fasta scores opt: 254 z-score: 355.8 E(): 1.9e-12 43.4% identity in 106 aa overlap.
  
  
 0.691
SCO6662
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
 
 0.687
SCO5424
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.653
SCO7004
SC8F11.30, probable carbohydrate kinase,len: 479 aa. Highly similar to many e.g. Bacillus subtilis SW:GLPK_BACSU(EMBL:M34393) glycerol kinase (EC 2.7.1.30), GlpK (496 aa), fasta scores opt: 688 z-score: 766.4 E():0 35.1% identity in 496 aa overlap. Contains a Pfam match to entry PF00370 FGGY, FGGY family of carbohydrate kinases.
  
  
 0.639
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.