node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCO0199 | SCO1174 | gene:17757783 | gene:17758757 | SCJ12.11c, probable alcohol dehydrogenase, len: 340 aa. Highly similar to many e.g. Bacillus stearothermophilus SW:ADH3_BACST (EMBL; Z27089) alcohol dehydrogenase (EC 1.1.1.1) (ADH-HT) (339 aa), fasta scores opt: 1281 z-score: 1383.7 E(): 0 55.2% identity in 337 aa overlap. Contains a PS00059 Zinc-containing alcohol dehydrogenases signature and a Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. | SCG11A.05, thcA, aldehyde dehydrogenase, len:534 aa; highly similar to SW:THCA_RHOSN (EMBL:U17129) Rhodococcus sp. (strain NI86/21) EPTC-inducible aldehyde dehydrogenase (EC 1.2.1.3) ThcA, 505 aa; fasta scores: opt: 2639 z-score: 3078.6 E(): 0; 75.7% identity in 506 aa overlap. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase and two matches to Prostie entries PS00687 Aldehyde dehydrogenases glutamic acid active site and PS00070 Aldehyde dehydrogenases cysteine active site. | 0.909 |
SCO0199 | SCO1705 | gene:17757783 | gene:17759299 | SCJ12.11c, probable alcohol dehydrogenase, len: 340 aa. Highly similar to many e.g. Bacillus stearothermophilus SW:ADH3_BACST (EMBL; Z27089) alcohol dehydrogenase (EC 1.1.1.1) (ADH-HT) (339 aa), fasta scores opt: 1281 z-score: 1383.7 E(): 0 55.2% identity in 337 aa overlap. Contains a PS00059 Zinc-containing alcohol dehydrogenases signature and a Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. | SCI30A.26c, probable alcohol dehydrogenase (zinc-binding), len: 365 aa; similar to many e.g. SW:ADH3_ECOLI alcohol dehydrogenase class III from Escherichia coli (369 aa) fasta scores; opt: 819, z-score: 864.3, E(): 0, (38.6% identity in 368 aa overlap). Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and Prosite matche to PS00059 Zinc-containing alcohol dehydrogenases signature. | 0.939 |
SCO0199 | SCO7362 | gene:17757783 | gene:17765022 | SCJ12.11c, probable alcohol dehydrogenase, len: 340 aa. Highly similar to many e.g. Bacillus stearothermophilus SW:ADH3_BACST (EMBL; Z27089) alcohol dehydrogenase (EC 1.1.1.1) (ADH-HT) (339 aa), fasta scores opt: 1281 z-score: 1383.7 E(): 0 55.2% identity in 337 aa overlap. Contains a PS00059 Zinc-containing alcohol dehydrogenases signature and a Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. | Oxidoreductase; SC9H11.16c, oxidoreductase, len: 346 aa. Previously sequenced: Streptomyces coelicolor TR:BAA82700EMBL:AB017438) Orf3 (346 aa). Also highly similar to Corynebacterium sp. ST-10 TR:Q9ZN85(EMBL:AB020760) phenylacetaldehyde reductase (385 aa), fasta scores opt: 1382 z-score: 1438.5 E(): 0 65.2% identity in 316 aa overlap and many alcohol dehydrogenases e.g. from Sulfolobus solfataricus SW:ADH1_SULSO(EMBL:S51211) NAD-dependent alcohol dehydrogenase (EC 1.1.1.1) (347 aa), fasta scores opt: 595 z-score: 624.4 E(): 2.5e-27 32.7% identity in 355 aa overlap. Contains a Prosite h [...] | 0.920 |
SCO0199 | SCP1.54c | gene:17757783 | gene:17765560 | SCJ12.11c, probable alcohol dehydrogenase, len: 340 aa. Highly similar to many e.g. Bacillus stearothermophilus SW:ADH3_BACST (EMBL; Z27089) alcohol dehydrogenase (EC 1.1.1.1) (ADH-HT) (339 aa), fasta scores opt: 1281 z-score: 1383.7 E(): 0 55.2% identity in 337 aa overlap. Contains a PS00059 Zinc-containing alcohol dehydrogenases signature and a Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. | Putative acetaldehyde dehydrogenase (acylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.520 |
SCO0763 | SCO1174 | gene:17758346 | gene:17758757 | SCF81.22, probable oxidoreductase, len: 535 aa; similar to SW:LA2M_MYCSM (EMBL:J05402) Mycobacterium smegmatis lactate 2-monooxygenase (EC 1.13.12.4) (lactate oxidase) La2M, 393 aa; fasta scores: opt: 1102 z-score: 1235.6 E(): 0; 44.6% identity in 379 aa overlap. Contains match to Pfam entry PF01070 FMN_dh, FMN-dependent dehydrogenase and to Prosite entry PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. | SCG11A.05, thcA, aldehyde dehydrogenase, len:534 aa; highly similar to SW:THCA_RHOSN (EMBL:U17129) Rhodococcus sp. (strain NI86/21) EPTC-inducible aldehyde dehydrogenase (EC 1.2.1.3) ThcA, 505 aa; fasta scores: opt: 2639 z-score: 3078.6 E(): 0; 75.7% identity in 506 aa overlap. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase and two matches to Prostie entries PS00687 Aldehyde dehydrogenases glutamic acid active site and PS00070 Aldehyde dehydrogenases cysteine active site. | 0.907 |
SCO0763 | SCO3563 | gene:17758346 | gene:17761185 | SCF81.22, probable oxidoreductase, len: 535 aa; similar to SW:LA2M_MYCSM (EMBL:J05402) Mycobacterium smegmatis lactate 2-monooxygenase (EC 1.13.12.4) (lactate oxidase) La2M, 393 aa; fasta scores: opt: 1102 z-score: 1235.6 E(): 0; 44.6% identity in 379 aa overlap. Contains match to Pfam entry PF01070 FMN_dh, FMN-dependent dehydrogenase and to Prosite entry PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.911 |
SCO0763 | SCO5424 | gene:17758346 | gene:17763076 | SCF81.22, probable oxidoreductase, len: 535 aa; similar to SW:LA2M_MYCSM (EMBL:J05402) Mycobacterium smegmatis lactate 2-monooxygenase (EC 1.13.12.4) (lactate oxidase) La2M, 393 aa; fasta scores: opt: 1102 z-score: 1235.6 E(): 0; 44.6% identity in 379 aa overlap. Contains match to Pfam entry PF01070 FMN_dh, FMN-dependent dehydrogenase and to Prosite entry PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.912 |
SCO0763 | SCO6195 | gene:17758346 | gene:17763854 | SCF81.22, probable oxidoreductase, len: 535 aa; similar to SW:LA2M_MYCSM (EMBL:J05402) Mycobacterium smegmatis lactate 2-monooxygenase (EC 1.13.12.4) (lactate oxidase) La2M, 393 aa; fasta scores: opt: 1102 z-score: 1235.6 E(): 0; 44.6% identity in 379 aa overlap. Contains match to Pfam entry PF01070 FMN_dh, FMN-dependent dehydrogenase and to Prosite entry PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. | SC2G5.16, probable acetyl-coenzyme A synthetase, len:558 aa; similar to many e.g. SW:ACSA_BACSU from Bacillus subtilis (572 aa) fasta scores; opt: 798, z-score: 878.3,E():0, (31.8% identity in 537 aa overlap). Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme, score 116.90, E-value 3.8e-31. Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme, score 116.90, E-value 3.8e-31. | 0.911 |
SCO1174 | SCO0199 | gene:17758757 | gene:17757783 | SCG11A.05, thcA, aldehyde dehydrogenase, len:534 aa; highly similar to SW:THCA_RHOSN (EMBL:U17129) Rhodococcus sp. (strain NI86/21) EPTC-inducible aldehyde dehydrogenase (EC 1.2.1.3) ThcA, 505 aa; fasta scores: opt: 2639 z-score: 3078.6 E(): 0; 75.7% identity in 506 aa overlap. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase and two matches to Prostie entries PS00687 Aldehyde dehydrogenases glutamic acid active site and PS00070 Aldehyde dehydrogenases cysteine active site. | SCJ12.11c, probable alcohol dehydrogenase, len: 340 aa. Highly similar to many e.g. Bacillus stearothermophilus SW:ADH3_BACST (EMBL; Z27089) alcohol dehydrogenase (EC 1.1.1.1) (ADH-HT) (339 aa), fasta scores opt: 1281 z-score: 1383.7 E(): 0 55.2% identity in 337 aa overlap. Contains a PS00059 Zinc-containing alcohol dehydrogenases signature and a Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. | 0.909 |
SCO1174 | SCO0763 | gene:17758757 | gene:17758346 | SCG11A.05, thcA, aldehyde dehydrogenase, len:534 aa; highly similar to SW:THCA_RHOSN (EMBL:U17129) Rhodococcus sp. (strain NI86/21) EPTC-inducible aldehyde dehydrogenase (EC 1.2.1.3) ThcA, 505 aa; fasta scores: opt: 2639 z-score: 3078.6 E(): 0; 75.7% identity in 506 aa overlap. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase and two matches to Prostie entries PS00687 Aldehyde dehydrogenases glutamic acid active site and PS00070 Aldehyde dehydrogenases cysteine active site. | SCF81.22, probable oxidoreductase, len: 535 aa; similar to SW:LA2M_MYCSM (EMBL:J05402) Mycobacterium smegmatis lactate 2-monooxygenase (EC 1.13.12.4) (lactate oxidase) La2M, 393 aa; fasta scores: opt: 1102 z-score: 1235.6 E(): 0; 44.6% identity in 379 aa overlap. Contains match to Pfam entry PF01070 FMN_dh, FMN-dependent dehydrogenase and to Prosite entry PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. | 0.907 |
SCO1174 | SCO1705 | gene:17758757 | gene:17759299 | SCG11A.05, thcA, aldehyde dehydrogenase, len:534 aa; highly similar to SW:THCA_RHOSN (EMBL:U17129) Rhodococcus sp. (strain NI86/21) EPTC-inducible aldehyde dehydrogenase (EC 1.2.1.3) ThcA, 505 aa; fasta scores: opt: 2639 z-score: 3078.6 E(): 0; 75.7% identity in 506 aa overlap. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase and two matches to Prostie entries PS00687 Aldehyde dehydrogenases glutamic acid active site and PS00070 Aldehyde dehydrogenases cysteine active site. | SCI30A.26c, probable alcohol dehydrogenase (zinc-binding), len: 365 aa; similar to many e.g. SW:ADH3_ECOLI alcohol dehydrogenase class III from Escherichia coli (369 aa) fasta scores; opt: 819, z-score: 864.3, E(): 0, (38.6% identity in 368 aa overlap). Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and Prosite matche to PS00059 Zinc-containing alcohol dehydrogenases signature. | 0.917 |
SCO1174 | SCO3563 | gene:17758757 | gene:17761185 | SCG11A.05, thcA, aldehyde dehydrogenase, len:534 aa; highly similar to SW:THCA_RHOSN (EMBL:U17129) Rhodococcus sp. (strain NI86/21) EPTC-inducible aldehyde dehydrogenase (EC 1.2.1.3) ThcA, 505 aa; fasta scores: opt: 2639 z-score: 3078.6 E(): 0; 75.7% identity in 506 aa overlap. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase and two matches to Prostie entries PS00687 Aldehyde dehydrogenases glutamic acid active site and PS00070 Aldehyde dehydrogenases cysteine active site. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.929 |
SCO1174 | SCO4271 | gene:17758757 | gene:17761916 | SCG11A.05, thcA, aldehyde dehydrogenase, len:534 aa; highly similar to SW:THCA_RHOSN (EMBL:U17129) Rhodococcus sp. (strain NI86/21) EPTC-inducible aldehyde dehydrogenase (EC 1.2.1.3) ThcA, 505 aa; fasta scores: opt: 2639 z-score: 3078.6 E(): 0; 75.7% identity in 506 aa overlap. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase and two matches to Prostie entries PS00687 Aldehyde dehydrogenases glutamic acid active site and PS00070 Aldehyde dehydrogenases cysteine active site. | SCD95A.04, probable NADP-dependent alcohol dehydrogenase, len: 378 aa; similar to SW:ADH_MYCTU (EMBL:AL021287) Mycobacterium tuberculosis NADP-dependent alcohol dehydrogenase (EC 1.1.1.2) Adh, 346 aa; fasta scores: opt: 986 z-score: 1074.5 E(): 0; 45.0% identity in 349 aa overlap. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and match to Prosite entry PS00059 Zinc-containing alcohol dehydrogenases signature. | 0.909 |
SCO1174 | SCO4945 | gene:17758757 | gene:17762594 | SCG11A.05, thcA, aldehyde dehydrogenase, len:534 aa; highly similar to SW:THCA_RHOSN (EMBL:U17129) Rhodococcus sp. (strain NI86/21) EPTC-inducible aldehyde dehydrogenase (EC 1.2.1.3) ThcA, 505 aa; fasta scores: opt: 2639 z-score: 3078.6 E(): 0; 75.7% identity in 506 aa overlap. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase and two matches to Prostie entries PS00687 Aldehyde dehydrogenases glutamic acid active site and PS00070 Aldehyde dehydrogenases cysteine active site. | 2SCK31.05, probable dehydrogenase, len: 346 aa; highly similar to SW:ADH_MYCTU (EMBL:AL021287) Mycobacterium bovis NADP-dependent alcohol dehydrogenase AdhC, 346 aa; fasta scores: opt: 1508 z-score: 1698.9 E(): 0; 64.5% identity in 346 aa overlap. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and matches to Prosite entries PS00059 Zinc-containing alcohol dehydrogenases signature and PS00017 ATP/GTP-binding site motif A (P-loop). | 0.909 |
SCO1174 | SCO5424 | gene:17758757 | gene:17763076 | SCG11A.05, thcA, aldehyde dehydrogenase, len:534 aa; highly similar to SW:THCA_RHOSN (EMBL:U17129) Rhodococcus sp. (strain NI86/21) EPTC-inducible aldehyde dehydrogenase (EC 1.2.1.3) ThcA, 505 aa; fasta scores: opt: 2639 z-score: 3078.6 E(): 0; 75.7% identity in 506 aa overlap. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase and two matches to Prostie entries PS00687 Aldehyde dehydrogenases glutamic acid active site and PS00070 Aldehyde dehydrogenases cysteine active site. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.938 |
SCO1174 | SCO6195 | gene:17758757 | gene:17763854 | SCG11A.05, thcA, aldehyde dehydrogenase, len:534 aa; highly similar to SW:THCA_RHOSN (EMBL:U17129) Rhodococcus sp. (strain NI86/21) EPTC-inducible aldehyde dehydrogenase (EC 1.2.1.3) ThcA, 505 aa; fasta scores: opt: 2639 z-score: 3078.6 E(): 0; 75.7% identity in 506 aa overlap. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase and two matches to Prostie entries PS00687 Aldehyde dehydrogenases glutamic acid active site and PS00070 Aldehyde dehydrogenases cysteine active site. | SC2G5.16, probable acetyl-coenzyme A synthetase, len:558 aa; similar to many e.g. SW:ACSA_BACSU from Bacillus subtilis (572 aa) fasta scores; opt: 798, z-score: 878.3,E():0, (31.8% identity in 537 aa overlap). Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme, score 116.90, E-value 3.8e-31. Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme, score 116.90, E-value 3.8e-31. | 0.929 |
SCO1174 | SCO7362 | gene:17758757 | gene:17765022 | SCG11A.05, thcA, aldehyde dehydrogenase, len:534 aa; highly similar to SW:THCA_RHOSN (EMBL:U17129) Rhodococcus sp. (strain NI86/21) EPTC-inducible aldehyde dehydrogenase (EC 1.2.1.3) ThcA, 505 aa; fasta scores: opt: 2639 z-score: 3078.6 E(): 0; 75.7% identity in 506 aa overlap. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase and two matches to Prostie entries PS00687 Aldehyde dehydrogenases glutamic acid active site and PS00070 Aldehyde dehydrogenases cysteine active site. | Oxidoreductase; SC9H11.16c, oxidoreductase, len: 346 aa. Previously sequenced: Streptomyces coelicolor TR:BAA82700EMBL:AB017438) Orf3 (346 aa). Also highly similar to Corynebacterium sp. ST-10 TR:Q9ZN85(EMBL:AB020760) phenylacetaldehyde reductase (385 aa), fasta scores opt: 1382 z-score: 1438.5 E(): 0 65.2% identity in 316 aa overlap and many alcohol dehydrogenases e.g. from Sulfolobus solfataricus SW:ADH1_SULSO(EMBL:S51211) NAD-dependent alcohol dehydrogenase (EC 1.1.1.1) (347 aa), fasta scores opt: 595 z-score: 624.4 E(): 2.5e-27 32.7% identity in 355 aa overlap. Contains a Prosite h [...] | 0.909 |
SCO1174 | SCP1.54c | gene:17758757 | gene:17765560 | SCG11A.05, thcA, aldehyde dehydrogenase, len:534 aa; highly similar to SW:THCA_RHOSN (EMBL:U17129) Rhodococcus sp. (strain NI86/21) EPTC-inducible aldehyde dehydrogenase (EC 1.2.1.3) ThcA, 505 aa; fasta scores: opt: 2639 z-score: 3078.6 E(): 0; 75.7% identity in 506 aa overlap. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase and two matches to Prostie entries PS00687 Aldehyde dehydrogenases glutamic acid active site and PS00070 Aldehyde dehydrogenases cysteine active site. | Putative acetaldehyde dehydrogenase (acylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.909 |
SCO1705 | SCO0199 | gene:17759299 | gene:17757783 | SCI30A.26c, probable alcohol dehydrogenase (zinc-binding), len: 365 aa; similar to many e.g. SW:ADH3_ECOLI alcohol dehydrogenase class III from Escherichia coli (369 aa) fasta scores; opt: 819, z-score: 864.3, E(): 0, (38.6% identity in 368 aa overlap). Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and Prosite matche to PS00059 Zinc-containing alcohol dehydrogenases signature. | SCJ12.11c, probable alcohol dehydrogenase, len: 340 aa. Highly similar to many e.g. Bacillus stearothermophilus SW:ADH3_BACST (EMBL; Z27089) alcohol dehydrogenase (EC 1.1.1.1) (ADH-HT) (339 aa), fasta scores opt: 1281 z-score: 1383.7 E(): 0 55.2% identity in 337 aa overlap. Contains a PS00059 Zinc-containing alcohol dehydrogenases signature and a Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. | 0.939 |
SCO1705 | SCO1174 | gene:17759299 | gene:17758757 | SCI30A.26c, probable alcohol dehydrogenase (zinc-binding), len: 365 aa; similar to many e.g. SW:ADH3_ECOLI alcohol dehydrogenase class III from Escherichia coli (369 aa) fasta scores; opt: 819, z-score: 864.3, E(): 0, (38.6% identity in 368 aa overlap). Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and Prosite matche to PS00059 Zinc-containing alcohol dehydrogenases signature. | SCG11A.05, thcA, aldehyde dehydrogenase, len:534 aa; highly similar to SW:THCA_RHOSN (EMBL:U17129) Rhodococcus sp. (strain NI86/21) EPTC-inducible aldehyde dehydrogenase (EC 1.2.1.3) ThcA, 505 aa; fasta scores: opt: 2639 z-score: 3078.6 E(): 0; 75.7% identity in 506 aa overlap. Contains Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase and two matches to Prostie entries PS00687 Aldehyde dehydrogenases glutamic acid active site and PS00070 Aldehyde dehydrogenases cysteine active site. | 0.917 |