STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO12782SCG18.25, possible ATP/GTP-binding protein, len: 525 aa; similar to TR:O27682 (EMBL:AE000923) Methanobacterium thermoautotrophicum ABC transporter MTH1645, 561 aa; fasta scores: opt: 540 z-score: 600.5 E(): 5.8e-26; 30.1% identity in 372 aa overlap. Contains match to Prosite entry PS00017 ATP/GTP-binding site motif A (P-loop). (525 aa)    
Predicted Functional Partners:
SCO1279
Putative secreted protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
       0.669
SCO1277
Hypothetical protein 2SCG18.24; 2SCG18.24, unknown, len: 247 aa; identical to N-terminal region of TR:AAF35372 (EMBL:AF225460) Streptomyces coelicolor hypothetical 7.4 kD protein (fragment), 72 aa; fasta scores: opt: 452 z-score: 395.3 E(): 1.6e-14; 94.4% identity in 72 aa overlap. Contains 4 sets of different repeats: 2x conserved repeat: SGSSR, 6x degenerate repeat: NPLA(A/G), 7x degenerate repeat: G(A/G)A(G/Q/N) and 7x degenerate repeat: Q(G/V/L)(L/T).
       0.585
SCO1276
2SCG18.23, sigJ, RNA polymerase ECF sigma factor, len: 198 aa; identical to previously sequenced TR:AAF35371 (EMBL:AF225460) Streptomyces coelicolor RNA polymerase ECF sigma factor SigJ, 198 aa. Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily).
       0.461
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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