node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCO1488 | SCO1489 | gene:17759074 | gene:17759075 | Pyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | SC9C5.13, bldD, putative DNA-binding protein, len: 167 aa; identical to previously sequenced TR:O52732 (EMBL:AF045549) Streptomyces coelicolor putative DNA binding protein BldD, 167 aa. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. | 0.875 |
SCO1489 | SCO1488 | gene:17759075 | gene:17759074 | SC9C5.13, bldD, putative DNA-binding protein, len: 167 aa; identical to previously sequenced TR:O52732 (EMBL:AF045549) Streptomyces coelicolor putative DNA binding protein BldD, 167 aa. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. | Pyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.875 |
SCO1489 | SCO1541 | gene:17759075 | gene:17759129 | SC9C5.13, bldD, putative DNA-binding protein, len: 167 aa; identical to previously sequenced TR:O52732 (EMBL:AF045549) Streptomyces coelicolor putative DNA binding protein BldD, 167 aa. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. | Putative regulator; Involved in sporulation-specific cell division. Required for early stages of sporulation. Important in the process of growth cessation prior to sporulation-specific cell division. Recruits cell division protein FtsZ to the future septum sites and tethers the contractile ring structure (Z ring) to the cytoplasmic membrane during sporulation. Stimulates polymerization and filament length of FtsZ in vitro (By similarity). Belongs to the SsgA family. | 0.870 |
SCO1489 | SCO1839 | gene:17759075 | gene:17759436 | SC9C5.13, bldD, putative DNA-binding protein, len: 167 aa; identical to previously sequenced TR:O52732 (EMBL:AF045549) Streptomyces coelicolor putative DNA binding protein BldD, 167 aa. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. | SCI8.24c, possible transcriptional regulator, len: 73 aa. Contains a possible helix-turn-helix motif between residues 32..53 (+3.35 SD). | 0.726 |
SCO1489 | SCO1950 | gene:17759075 | gene:17759547 | SC9C5.13, bldD, putative DNA-binding protein, len: 167 aa; identical to previously sequenced TR:O52732 (EMBL:AF045549) Streptomyces coelicolor putative DNA binding protein BldD, 167 aa. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. | Hypothetical protein; Involved in cell division and chromosome segregation (By similarity). Involved in sporulation. May coordinate the cessation of aerial hyphae growth and subsequent chromosome segregation and/or septation. Required for expression of the ParB partioning protein during sporogenesis. Activates its own transcription and represses WhiB. Binds with low affinity to its own promoter and to the Parp2 sporulation-specific promoter. Also binds directly to the RNA polymerase sigma factor WhiG, leading to inhibition of WhiG-dependent transcription in a dose-dependent manner ; Be [...] | 0.894 |
SCO1489 | SCO2792 | gene:17759075 | gene:17760399 | SC9C5.13, bldD, putative DNA-binding protein, len: 167 aa; identical to previously sequenced TR:O52732 (EMBL:AF045549) Streptomyces coelicolor putative DNA binding protein BldD, 167 aa. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. | SCC105.23, adpA, araC-family transcriptional regulator, len: 398 aa; highly similar to TR:BAA86265 (EMBL:AB023785) Streptomyces griseus AdpA, 405 aa; fasta scores: opt: 2219 z-score: 2270.5 E(): 0; 84.4% identity in 410 aa overlap and to TR:Q9XA73 (EMBL:AL096822) Streptomyces coelicolor putative araC-family transcriptional regulator SCGD3.05, 334 aa; fasta scores: opt: 878 z-score: 904.2 E(): 0; 45.7% identity in 313 aa overlap. Contains Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family and match to Prosite entry PS00041 Bacterial regulat [...] | 0.865 |
SCO1489 | SCO2924 | gene:17759075 | gene:17760535 | SC9C5.13, bldD, putative DNA-binding protein, len: 167 aa; identical to previously sequenced TR:O52732 (EMBL:AF045549) Streptomyces coelicolor putative DNA binding protein BldD, 167 aa. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. | SCE19A.24, possible regulator, len: 142 aa; similar to TR:P95753 (EMBL:D50051), SsgA, Streptomyces griseus gene involved in regulation of sporulation and cell division (136 aa), fasta scores; opt: 291 z-score: 368.2 E(): 3.6e-13, 37.3% identity in 126 aa overlap and to SC5F2A.05C (EMBL:AL049587) S. coelicolor putative regulator (138 aa) (38.5% identity in 135 aa overlap). | 0.748 |
SCO1489 | SCO3926 | gene:17759075 | gene:17761553 | SC9C5.13, bldD, putative DNA-binding protein, len: 167 aa; identical to previously sequenced TR:O52732 (EMBL:AF045549) Streptomyces coelicolor putative DNA binding protein BldD, 167 aa. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. | SCQ11.09, ssgA, probable regulator, len: 136 aa; highly similar to TR:P95753 (EMBL:D50051), SsgA, Streptomyces griseus protein associated with sporulation and cell division (136 aa), fasta scores; opt: 715 z-score: 896.6 E(): 0, 77.9% identity in 136 aa overlap and similar to others from S.coelicolor e.g. SC5F2A.05c (EMBL:AL049587) possible regulator (138 aa) (35.7% identity in 115 aa overlap) and SC5H1.03 (EMBL:AL049863) possible regulator (142 aa) (2.5% identity in 114 aa overlap), both annotated by similarity to Streptomyces griseus SsgA. The start codon was selected by similarity t [...] | 0.914 |
SCO1489 | SCO4184 | gene:17759075 | gene:17761828 | SC9C5.13, bldD, putative DNA-binding protein, len: 167 aa; identical to previously sequenced TR:O52732 (EMBL:AF045549) Streptomyces coelicolor putative DNA binding protein BldD, 167 aa. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. | SCD66.21, amfC, aerial mycelium formation, len: 222 aa; identical to previously sequenced TR:Q54191 (EMBL:D63677) Streptomyces coelicolor aerial micelium formation AmfC, 222 aa. | 0.770 |
SCO1489 | SCO5621 | gene:17759075 | gene:17763279 | SC9C5.13, bldD, putative DNA-binding protein, len: 167 aa; identical to previously sequenced TR:O52732 (EMBL:AF045549) Streptomyces coelicolor putative DNA binding protein BldD, 167 aa. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. | RNA polymerase sigma factor WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.946 |
SCO1489 | SCO5723 | gene:17759075 | gene:17763379 | SC9C5.13, bldD, putative DNA-binding protein, len: 167 aa; identical to previously sequenced TR:O52732 (EMBL:AF045549) Streptomyces coelicolor putative DNA binding protein BldD, 167 aa. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. | SC3C3.09c, possible regulator, BldB, len: 98 aa; identical to TR:Q53842 (EMBL:U28930) bldB (98 aa) and similar to S. coelicolor TR:Q53896 (EMBL:X60316) AbaA ORFD (75 aa), fasta scores; opt: 150 z-score: 201.9 E(): 0.00055, 47.4% identity in 57 aa overlap. | 0.848 |
SCO1541 | SCO1489 | gene:17759129 | gene:17759075 | Putative regulator; Involved in sporulation-specific cell division. Required for early stages of sporulation. Important in the process of growth cessation prior to sporulation-specific cell division. Recruits cell division protein FtsZ to the future septum sites and tethers the contractile ring structure (Z ring) to the cytoplasmic membrane during sporulation. Stimulates polymerization and filament length of FtsZ in vitro (By similarity). Belongs to the SsgA family. | SC9C5.13, bldD, putative DNA-binding protein, len: 167 aa; identical to previously sequenced TR:O52732 (EMBL:AF045549) Streptomyces coelicolor putative DNA binding protein BldD, 167 aa. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. | 0.870 |
SCO1541 | SCO1839 | gene:17759129 | gene:17759436 | Putative regulator; Involved in sporulation-specific cell division. Required for early stages of sporulation. Important in the process of growth cessation prior to sporulation-specific cell division. Recruits cell division protein FtsZ to the future septum sites and tethers the contractile ring structure (Z ring) to the cytoplasmic membrane during sporulation. Stimulates polymerization and filament length of FtsZ in vitro (By similarity). Belongs to the SsgA family. | SCI8.24c, possible transcriptional regulator, len: 73 aa. Contains a possible helix-turn-helix motif between residues 32..53 (+3.35 SD). | 0.767 |
SCO1541 | SCO1950 | gene:17759129 | gene:17759547 | Putative regulator; Involved in sporulation-specific cell division. Required for early stages of sporulation. Important in the process of growth cessation prior to sporulation-specific cell division. Recruits cell division protein FtsZ to the future septum sites and tethers the contractile ring structure (Z ring) to the cytoplasmic membrane during sporulation. Stimulates polymerization and filament length of FtsZ in vitro (By similarity). Belongs to the SsgA family. | Hypothetical protein; Involved in cell division and chromosome segregation (By similarity). Involved in sporulation. May coordinate the cessation of aerial hyphae growth and subsequent chromosome segregation and/or septation. Required for expression of the ParB partioning protein during sporogenesis. Activates its own transcription and represses WhiB. Binds with low affinity to its own promoter and to the Parp2 sporulation-specific promoter. Also binds directly to the RNA polymerase sigma factor WhiG, leading to inhibition of WhiG-dependent transcription in a dose-dependent manner ; Be [...] | 0.560 |
SCO1541 | SCO4184 | gene:17759129 | gene:17761828 | Putative regulator; Involved in sporulation-specific cell division. Required for early stages of sporulation. Important in the process of growth cessation prior to sporulation-specific cell division. Recruits cell division protein FtsZ to the future septum sites and tethers the contractile ring structure (Z ring) to the cytoplasmic membrane during sporulation. Stimulates polymerization and filament length of FtsZ in vitro (By similarity). Belongs to the SsgA family. | SCD66.21, amfC, aerial mycelium formation, len: 222 aa; identical to previously sequenced TR:Q54191 (EMBL:D63677) Streptomyces coelicolor aerial micelium formation AmfC, 222 aa. | 0.700 |
SCO1541 | SCO5621 | gene:17759129 | gene:17763279 | Putative regulator; Involved in sporulation-specific cell division. Required for early stages of sporulation. Important in the process of growth cessation prior to sporulation-specific cell division. Recruits cell division protein FtsZ to the future septum sites and tethers the contractile ring structure (Z ring) to the cytoplasmic membrane during sporulation. Stimulates polymerization and filament length of FtsZ in vitro (By similarity). Belongs to the SsgA family. | RNA polymerase sigma factor WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.684 |
SCO1839 | SCO1489 | gene:17759436 | gene:17759075 | SCI8.24c, possible transcriptional regulator, len: 73 aa. Contains a possible helix-turn-helix motif between residues 32..53 (+3.35 SD). | SC9C5.13, bldD, putative DNA-binding protein, len: 167 aa; identical to previously sequenced TR:O52732 (EMBL:AF045549) Streptomyces coelicolor putative DNA binding protein BldD, 167 aa. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix. | 0.726 |
SCO1839 | SCO1541 | gene:17759436 | gene:17759129 | SCI8.24c, possible transcriptional regulator, len: 73 aa. Contains a possible helix-turn-helix motif between residues 32..53 (+3.35 SD). | Putative regulator; Involved in sporulation-specific cell division. Required for early stages of sporulation. Important in the process of growth cessation prior to sporulation-specific cell division. Recruits cell division protein FtsZ to the future septum sites and tethers the contractile ring structure (Z ring) to the cytoplasmic membrane during sporulation. Stimulates polymerization and filament length of FtsZ in vitro (By similarity). Belongs to the SsgA family. | 0.767 |
SCO1839 | SCO2924 | gene:17759436 | gene:17760535 | SCI8.24c, possible transcriptional regulator, len: 73 aa. Contains a possible helix-turn-helix motif between residues 32..53 (+3.35 SD). | SCE19A.24, possible regulator, len: 142 aa; similar to TR:P95753 (EMBL:D50051), SsgA, Streptomyces griseus gene involved in regulation of sporulation and cell division (136 aa), fasta scores; opt: 291 z-score: 368.2 E(): 3.6e-13, 37.3% identity in 126 aa overlap and to SC5F2A.05C (EMBL:AL049587) S. coelicolor putative regulator (138 aa) (38.5% identity in 135 aa overlap). | 0.670 |
SCO1839 | SCO3926 | gene:17759436 | gene:17761553 | SCI8.24c, possible transcriptional regulator, len: 73 aa. Contains a possible helix-turn-helix motif between residues 32..53 (+3.35 SD). | SCQ11.09, ssgA, probable regulator, len: 136 aa; highly similar to TR:P95753 (EMBL:D50051), SsgA, Streptomyces griseus protein associated with sporulation and cell division (136 aa), fasta scores; opt: 715 z-score: 896.6 E(): 0, 77.9% identity in 136 aa overlap and similar to others from S.coelicolor e.g. SC5F2A.05c (EMBL:AL049587) possible regulator (138 aa) (35.7% identity in 115 aa overlap) and SC5H1.03 (EMBL:AL049863) possible regulator (142 aa) (2.5% identity in 114 aa overlap), both annotated by similarity to Streptomyces griseus SsgA. The start codon was selected by similarity t [...] | 0.735 |