node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCO0196 | SCO2690 | gene:17757780 | gene:17760297 | Hypothetical protein SCJ12.08; SCJ12.08, unknown, len:134 aa. Shares a low level of similarity with Mycobacterium tuberculosis TR:O53597 (EMBL; AL021426) hypothetical 24.0 KD protein MTV028.10C (224 aa), fasta scores opt: 119 z-score: 159.2 E(): 0.1 32.8% identity in 116 aa overlap. | SCC61A.11, possible membrane transport protein, len: 454aa; similar to eg. TR:Q54309 (EMBL:X86780) membrane transport protein from rapamycin biosynthetic gene cluster of Streptomyces hygroscopicus (453 aa) fasta scores; opt: 546, z-score: 566.6, E(): 4.2e-24, 27.7% identity in 452 aa overlap. Contains possible membrane-spanning hydrophobic regions. | 0.463 |
SCO2686 | SCO2690 | gene:17760293 | gene:17760297 | SCC61A.07c, possible luxR-family transcriptional regulator, len: 338aa; similar to many eg. TR:Q56084 (EMBL:D63904) erythropoiesis-stimulating protein from Streptomyces thermoviolaceus (334 aa) fasta scores; opt: 393, z-score: 460.3, E(): 3.5e-18, 32.5% identity in 295 aa overlap and SW:Q01108 (BRPA_STRHY) bialaphos biosynthetic pathway regulatory protein from Streptomyces hygroscopicus (256 aa) fasta scores; opt: 178, z-score: 213.5, E(): 0.0002, 25.1% identity in 255 aa overlap. Contains Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family and helix-turn-helix [...] | SCC61A.11, possible membrane transport protein, len: 454aa; similar to eg. TR:Q54309 (EMBL:X86780) membrane transport protein from rapamycin biosynthetic gene cluster of Streptomyces hygroscopicus (453 aa) fasta scores; opt: 546, z-score: 566.6, E(): 4.2e-24, 27.7% identity in 452 aa overlap. Contains possible membrane-spanning hydrophobic regions. | 0.429 |
SCO2687 | SCO2688 | gene:17760294 | gene:17760295 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.997 |
SCO2687 | SCO2689 | gene:17760294 | gene:17760296 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | SCC61A.10, possible membrane protein, len: 375aa; contains possible membrane-spanning hydrophobic regions. | 0.636 |
SCO2687 | SCO2690 | gene:17760294 | gene:17760297 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | SCC61A.11, possible membrane transport protein, len: 454aa; similar to eg. TR:Q54309 (EMBL:X86780) membrane transport protein from rapamycin biosynthetic gene cluster of Streptomyces hygroscopicus (453 aa) fasta scores; opt: 546, z-score: 566.6, E(): 4.2e-24, 27.7% identity in 452 aa overlap. Contains possible membrane-spanning hydrophobic regions. | 0.682 |
SCO2687 | SCO2691 | gene:17760294 | gene:17760298 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | Hypothetical protein; SCC61A.12, unknown, len: 385aa. | 0.670 |
SCO2687 | SCO2692 | gene:17760294 | gene:17760299 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | Putative repetative protein; SCC61A.13, possible repetetive protein, len: 626 aa; contains eleven (weak) Pfam matches to entry PF00400 WD40, WD domain, G-beta repeat and three Prosite matches to PS00678 Trp-Asp (WD) repeats signature. | 0.498 |
SCO2688 | SCO2687 | gene:17760295 | gene:17760294 | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.997 |
SCO2688 | SCO2689 | gene:17760295 | gene:17760296 | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | SCC61A.10, possible membrane protein, len: 375aa; contains possible membrane-spanning hydrophobic regions. | 0.776 |
SCO2688 | SCO2690 | gene:17760295 | gene:17760297 | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | SCC61A.11, possible membrane transport protein, len: 454aa; similar to eg. TR:Q54309 (EMBL:X86780) membrane transport protein from rapamycin biosynthetic gene cluster of Streptomyces hygroscopicus (453 aa) fasta scores; opt: 546, z-score: 566.6, E(): 4.2e-24, 27.7% identity in 452 aa overlap. Contains possible membrane-spanning hydrophobic regions. | 0.774 |
SCO2688 | SCO2691 | gene:17760295 | gene:17760298 | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; SCC61A.12, unknown, len: 385aa. | 0.817 |
SCO2688 | SCO2692 | gene:17760295 | gene:17760299 | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Putative repetative protein; SCC61A.13, possible repetetive protein, len: 626 aa; contains eleven (weak) Pfam matches to entry PF00400 WD40, WD domain, G-beta repeat and three Prosite matches to PS00678 Trp-Asp (WD) repeats signature. | 0.546 |
SCO2688 | SCO2693 | gene:17760295 | gene:17760300 | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | SCC61A.14, possible oxygenase (putative secreted protein), len: 333 aa; similar to others from Streptomyces spp. e.g. TR:Q05582 (EMBL:L06214) clavaminate synthase 2 from Streptomyces clavuligerus (325 aa) fasta scores; opt: 582, z-score: 633.2, E(): 8.2e-28, 37.5% identity in 317 aa overlap and TR:Q9Z4Z5 (EMBL:AL035707) putative oxygenase from Streptomyces coelicolor (333 aa) opt: 1205, z-score: 1302.5, E(): 0, 59.4% identity in 320 aa overlap. Contains possible N-terminal region signal peptide sequence. | 0.455 |
SCO2688 | SCO2694 | gene:17760295 | gene:17760301 | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; SCC61A.15, unknown, len: 180aa. | 0.899 |
SCO2689 | SCO2687 | gene:17760296 | gene:17760294 | SCC61A.10, possible membrane protein, len: 375aa; contains possible membrane-spanning hydrophobic regions. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.636 |
SCO2689 | SCO2688 | gene:17760296 | gene:17760295 | SCC61A.10, possible membrane protein, len: 375aa; contains possible membrane-spanning hydrophobic regions. | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.776 |
SCO2689 | SCO2690 | gene:17760296 | gene:17760297 | SCC61A.10, possible membrane protein, len: 375aa; contains possible membrane-spanning hydrophobic regions. | SCC61A.11, possible membrane transport protein, len: 454aa; similar to eg. TR:Q54309 (EMBL:X86780) membrane transport protein from rapamycin biosynthetic gene cluster of Streptomyces hygroscopicus (453 aa) fasta scores; opt: 546, z-score: 566.6, E(): 4.2e-24, 27.7% identity in 452 aa overlap. Contains possible membrane-spanning hydrophobic regions. | 0.788 |
SCO2689 | SCO2691 | gene:17760296 | gene:17760298 | SCC61A.10, possible membrane protein, len: 375aa; contains possible membrane-spanning hydrophobic regions. | Hypothetical protein; SCC61A.12, unknown, len: 385aa. | 0.802 |
SCO2689 | SCO2692 | gene:17760296 | gene:17760299 | SCC61A.10, possible membrane protein, len: 375aa; contains possible membrane-spanning hydrophobic regions. | Putative repetative protein; SCC61A.13, possible repetetive protein, len: 626 aa; contains eleven (weak) Pfam matches to entry PF00400 WD40, WD domain, G-beta repeat and three Prosite matches to PS00678 Trp-Asp (WD) repeats signature. | 0.466 |
SCO2689 | SCO2693 | gene:17760296 | gene:17760300 | SCC61A.10, possible membrane protein, len: 375aa; contains possible membrane-spanning hydrophobic regions. | SCC61A.14, possible oxygenase (putative secreted protein), len: 333 aa; similar to others from Streptomyces spp. e.g. TR:Q05582 (EMBL:L06214) clavaminate synthase 2 from Streptomyces clavuligerus (325 aa) fasta scores; opt: 582, z-score: 633.2, E(): 8.2e-28, 37.5% identity in 317 aa overlap and TR:Q9Z4Z5 (EMBL:AL035707) putative oxygenase from Streptomyces coelicolor (333 aa) opt: 1205, z-score: 1302.5, E(): 0, 59.4% identity in 320 aa overlap. Contains possible N-terminal region signal peptide sequence. | 0.455 |