Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SCO0208 | SCO0546 | gene:17757792 | gene:17758129 | SCJ12.20, pyruvate phosphate dikinase, len: 898 aa. Highly similar to many pyruvate phosphate dikinases e.g. Clostridium symbiosum SW:PODK_CLOSY (EMBL; M60920)(EC 2.7.9.1) (873 aa), fasta scores opt: 1626 z-score: 1761.3 E():0 48.7% identity in 895 aa overlap and Microbispora rosea SW:BAA76347 (EMBL; AB025020) (878 aa), fasta scores opt: 3060 z-score: 3317.5 E(): 0 67.5% identity in 898 aa overlap. Contains a PS00370 PEP-utilizing enzymes phosphorylation site signature, Pfam match to entry PF01326 PPDK_N_term, Pyruvate phosphate dikinase, PEP/pyruvate binding domain and a Pfam match to [...] | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.958 |
| SCO0208 | SCO2014 | gene:17757792 | gene:17759612 | SCJ12.20, pyruvate phosphate dikinase, len: 898 aa. Highly similar to many pyruvate phosphate dikinases e.g. Clostridium symbiosum SW:PODK_CLOSY (EMBL; M60920)(EC 2.7.9.1) (873 aa), fasta scores opt: 1626 z-score: 1761.3 E():0 48.7% identity in 895 aa overlap and Microbispora rosea SW:BAA76347 (EMBL; AB025020) (878 aa), fasta scores opt: 3060 z-score: 3317.5 E(): 0 67.5% identity in 898 aa overlap. Contains a PS00370 PEP-utilizing enzymes phosphorylation site signature, Pfam match to entry PF01326 PPDK_N_term, Pyruvate phosphate dikinase, PEP/pyruvate binding domain and a Pfam match to [...] | SC7H2.28c, pyk1, pyruvate kinase, len: 478 aa; strongly similar to many e.g. SW:KPYK_CORGL pyruvate kinase from Corynebacterium glutamicum (475 aa) fasta scores; opt: 1800, z-score: 2008.1, E(): 0, (59.6% identity in 473 aa overlap). Contains Pfam match to entry PF00224 PK, Pyruvate kinase and Prosite match to PS00110 Pyruvate kinase active site signature. | 0.911 |
| SCO0208 | SCO3096 | gene:17757792 | gene:17760712 | SCJ12.20, pyruvate phosphate dikinase, len: 898 aa. Highly similar to many pyruvate phosphate dikinases e.g. Clostridium symbiosum SW:PODK_CLOSY (EMBL; M60920)(EC 2.7.9.1) (873 aa), fasta scores opt: 1626 z-score: 1761.3 E():0 48.7% identity in 895 aa overlap and Microbispora rosea SW:BAA76347 (EMBL; AB025020) (878 aa), fasta scores opt: 3060 z-score: 3317.5 E(): 0 67.5% identity in 898 aa overlap. Contains a PS00370 PEP-utilizing enzymes phosphorylation site signature, Pfam match to entry PF01326 PPDK_N_term, Pyruvate phosphate dikinase, PEP/pyruvate binding domain and a Pfam match to [...] | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.915 |
| SCO0208 | SCO3127 | gene:17757792 | gene:17760744 | SCJ12.20, pyruvate phosphate dikinase, len: 898 aa. Highly similar to many pyruvate phosphate dikinases e.g. Clostridium symbiosum SW:PODK_CLOSY (EMBL; M60920)(EC 2.7.9.1) (873 aa), fasta scores opt: 1626 z-score: 1761.3 E():0 48.7% identity in 895 aa overlap and Microbispora rosea SW:BAA76347 (EMBL; AB025020) (878 aa), fasta scores opt: 3060 z-score: 3317.5 E(): 0 67.5% identity in 898 aa overlap. Contains a PS00370 PEP-utilizing enzymes phosphorylation site signature, Pfam match to entry PF01326 PPDK_N_term, Pyruvate phosphate dikinase, PEP/pyruvate binding domain and a Pfam match to [...] | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.930 |
| SCO0208 | SCO4827 | gene:17757792 | gene:17762476 | SCJ12.20, pyruvate phosphate dikinase, len: 898 aa. Highly similar to many pyruvate phosphate dikinases e.g. Clostridium symbiosum SW:PODK_CLOSY (EMBL; M60920)(EC 2.7.9.1) (873 aa), fasta scores opt: 1626 z-score: 1761.3 E():0 48.7% identity in 895 aa overlap and Microbispora rosea SW:BAA76347 (EMBL; AB025020) (878 aa), fasta scores opt: 3060 z-score: 3317.5 E(): 0 67.5% identity in 898 aa overlap. Contains a PS00370 PEP-utilizing enzymes phosphorylation site signature, Pfam match to entry PF01326 PPDK_N_term, Pyruvate phosphate dikinase, PEP/pyruvate binding domain and a Pfam match to [...] | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Exhibits remarkably higher catalytic efficiency for oxaloacetate reduction than for malate oxidation in vitro. Shows a high specificity for NAD(H), being almost inactive with NADP(H). | 0.615 |
| SCO0208 | SCO4979 | gene:17757792 | gene:17762628 | SCJ12.20, pyruvate phosphate dikinase, len: 898 aa. Highly similar to many pyruvate phosphate dikinases e.g. Clostridium symbiosum SW:PODK_CLOSY (EMBL; M60920)(EC 2.7.9.1) (873 aa), fasta scores opt: 1626 z-score: 1761.3 E():0 48.7% identity in 895 aa overlap and Microbispora rosea SW:BAA76347 (EMBL; AB025020) (878 aa), fasta scores opt: 3060 z-score: 3317.5 E(): 0 67.5% identity in 898 aa overlap. Contains a PS00370 PEP-utilizing enzymes phosphorylation site signature, Pfam match to entry PF01326 PPDK_N_term, Pyruvate phosphate dikinase, PEP/pyruvate binding domain and a Pfam match to [...] | Putative phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.953 |
| SCO0208 | SCO5423 | gene:17757792 | gene:17763075 | SCJ12.20, pyruvate phosphate dikinase, len: 898 aa. Highly similar to many pyruvate phosphate dikinases e.g. Clostridium symbiosum SW:PODK_CLOSY (EMBL; M60920)(EC 2.7.9.1) (873 aa), fasta scores opt: 1626 z-score: 1761.3 E():0 48.7% identity in 895 aa overlap and Microbispora rosea SW:BAA76347 (EMBL; AB025020) (878 aa), fasta scores opt: 3060 z-score: 3317.5 E(): 0 67.5% identity in 898 aa overlap. Contains a PS00370 PEP-utilizing enzymes phosphorylation site signature, Pfam match to entry PF01326 PPDK_N_term, Pyruvate phosphate dikinase, PEP/pyruvate binding domain and a Pfam match to [...] | SC8F4.27c, pyk2, pyruvate kinase, len: 476 aa; strongly similar to many e.g. SW:Q46078 (KPYK_CORGL) pyruvate kinase from Corynebacterium glutamicum (Brevibacterium flavum) (475 aa) fasta scores; opt: 1693, z-score: 1907.7, E(): 0, 55.3% identity in 474 aa overlap and TRNEW:CAB52070 (EMBL:AL109732) pyruvate kinase from Streptomyces coelicolor (478 aa) fasta scores; opt: 2185, z-score: 2461.2, E(): 0, 69.3% identity in 473 aa overlap. Contains Pfam match to entry PF00224 PK, Pyruvate kinase and Prosite match to PS00110 Pyruvate kinase active site signature. | 0.911 |
| SCO0208 | SCO7638 | gene:17757792 | gene:17765298 | SCJ12.20, pyruvate phosphate dikinase, len: 898 aa. Highly similar to many pyruvate phosphate dikinases e.g. Clostridium symbiosum SW:PODK_CLOSY (EMBL; M60920)(EC 2.7.9.1) (873 aa), fasta scores opt: 1626 z-score: 1761.3 E():0 48.7% identity in 895 aa overlap and Microbispora rosea SW:BAA76347 (EMBL; AB025020) (878 aa), fasta scores opt: 3060 z-score: 3317.5 E(): 0 67.5% identity in 898 aa overlap. Contains a PS00370 PEP-utilizing enzymes phosphorylation site signature, Pfam match to entry PF01326 PPDK_N_term, Pyruvate phosphate dikinase, PEP/pyruvate binding domain and a Pfam match to [...] | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.915 |
| SCO0546 | SCO0208 | gene:17758129 | gene:17757792 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | SCJ12.20, pyruvate phosphate dikinase, len: 898 aa. Highly similar to many pyruvate phosphate dikinases e.g. Clostridium symbiosum SW:PODK_CLOSY (EMBL; M60920)(EC 2.7.9.1) (873 aa), fasta scores opt: 1626 z-score: 1761.3 E():0 48.7% identity in 895 aa overlap and Microbispora rosea SW:BAA76347 (EMBL; AB025020) (878 aa), fasta scores opt: 3060 z-score: 3317.5 E(): 0 67.5% identity in 898 aa overlap. Contains a PS00370 PEP-utilizing enzymes phosphorylation site signature, Pfam match to entry PF01326 PPDK_N_term, Pyruvate phosphate dikinase, PEP/pyruvate binding domain and a Pfam match to [...] | 0.958 |
| SCO0546 | SCO2014 | gene:17758129 | gene:17759612 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | SC7H2.28c, pyk1, pyruvate kinase, len: 478 aa; strongly similar to many e.g. SW:KPYK_CORGL pyruvate kinase from Corynebacterium glutamicum (475 aa) fasta scores; opt: 1800, z-score: 2008.1, E(): 0, (59.6% identity in 473 aa overlap). Contains Pfam match to entry PF00224 PK, Pyruvate kinase and Prosite match to PS00110 Pyruvate kinase active site signature. | 0.953 |
| SCO0546 | SCO2736 | gene:17758129 | gene:17760343 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | SCC57A.07c, citA, citrate synthase, len: 429 aa. Previously sequenced and characterised: Streptomyces coelicolor TR:AAF14286(EMBL:AF181118) citrate synthase (citA). Contains a Prosite hit to PS00480 Citrate synthase signature and a Pfam match to entry PF00285 citrate_synt, Citrate synthase. | 0.977 |
| SCO0546 | SCO3096 | gene:17758129 | gene:17760712 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.546 |
| SCO0546 | SCO3127 | gene:17758129 | gene:17760744 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.987 |
| SCO0546 | SCO4388 | gene:17758129 | gene:17762033 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | SCD10.20, probable citrate synthase, len: 387 aa; similar to SW:CISY_BACSU (EMBL:U05256) Bacillus subtilis citrate synthase I (EC 4.1.3.7) CitA, 366 aa; fasta scores: opt: 615 z-score: 685.9 E(): 9.9e-31; 36.7% identity in 360 aa overlap and to TR:O70008 (EMBL:AL022374) Streptomyces coelicolor citrate synthase (EC 4.1.3.7) SC5B8.22, 390 aa; fasta scores: opt: 780 z-score: 867.9 E(): 0; 41.0% identity in 371 aa overlap. Contains 2 Pfam matches to entry PF00285 citrate_synt, Citrate synthase and match to Prosite entry PS00480 Citrate synthase signature. | 0.958 |
| SCO0546 | SCO4827 | gene:17758129 | gene:17762476 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Exhibits remarkably higher catalytic efficiency for oxaloacetate reduction than for malate oxidation in vitro. Shows a high specificity for NAD(H), being almost inactive with NADP(H). | 0.970 |
| SCO0546 | SCO4979 | gene:17758129 | gene:17762628 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Putative phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.981 |
| SCO0546 | SCO5423 | gene:17758129 | gene:17763075 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | SC8F4.27c, pyk2, pyruvate kinase, len: 476 aa; strongly similar to many e.g. SW:Q46078 (KPYK_CORGL) pyruvate kinase from Corynebacterium glutamicum (Brevibacterium flavum) (475 aa) fasta scores; opt: 1693, z-score: 1907.7, E(): 0, 55.3% identity in 474 aa overlap and TRNEW:CAB52070 (EMBL:AL109732) pyruvate kinase from Streptomyces coelicolor (478 aa) fasta scores; opt: 2185, z-score: 2461.2, E(): 0, 69.3% identity in 473 aa overlap. Contains Pfam match to entry PF00224 PK, Pyruvate kinase and Prosite match to PS00110 Pyruvate kinase active site signature. | 0.953 |
| SCO0546 | SCO7638 | gene:17758129 | gene:17765298 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.535 |
| SCO2014 | SCO0208 | gene:17759612 | gene:17757792 | SC7H2.28c, pyk1, pyruvate kinase, len: 478 aa; strongly similar to many e.g. SW:KPYK_CORGL pyruvate kinase from Corynebacterium glutamicum (475 aa) fasta scores; opt: 1800, z-score: 2008.1, E(): 0, (59.6% identity in 473 aa overlap). Contains Pfam match to entry PF00224 PK, Pyruvate kinase and Prosite match to PS00110 Pyruvate kinase active site signature. | SCJ12.20, pyruvate phosphate dikinase, len: 898 aa. Highly similar to many pyruvate phosphate dikinases e.g. Clostridium symbiosum SW:PODK_CLOSY (EMBL; M60920)(EC 2.7.9.1) (873 aa), fasta scores opt: 1626 z-score: 1761.3 E():0 48.7% identity in 895 aa overlap and Microbispora rosea SW:BAA76347 (EMBL; AB025020) (878 aa), fasta scores opt: 3060 z-score: 3317.5 E(): 0 67.5% identity in 898 aa overlap. Contains a PS00370 PEP-utilizing enzymes phosphorylation site signature, Pfam match to entry PF01326 PPDK_N_term, Pyruvate phosphate dikinase, PEP/pyruvate binding domain and a Pfam match to [...] | 0.911 |
| SCO2014 | SCO0546 | gene:17759612 | gene:17758129 | SC7H2.28c, pyk1, pyruvate kinase, len: 478 aa; strongly similar to many e.g. SW:KPYK_CORGL pyruvate kinase from Corynebacterium glutamicum (475 aa) fasta scores; opt: 1800, z-score: 2008.1, E(): 0, (59.6% identity in 473 aa overlap). Contains Pfam match to entry PF00224 PK, Pyruvate kinase and Prosite match to PS00110 Pyruvate kinase active site signature. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.953 |
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