node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCO2993 | SCO3236 | gene:17760605 | gene:17760854 | Hypothetical protein SCE50.21; SCE50.21, unknown, len: 184 aa. | Putative oxygenase; Catalyzes the 3-hydroxylation of L-asparagine to (2S,3S)-3- hydroxyasparagine. The 3-hydroxylated asparagine produced is incorporated at position 9 during the biosynthesis of the non- ribosomally synthesized calcium-dependent antibiotic (CDA), a 11- residue acidic lipopeptide lactone. Is able to hydroxylate only free L- asparagine, since it hydroxylates neither a CDA analog with unmodified Asn at position 9 nor a peptidyl-carrier-protein (PCP)-bound asparagine. Is not active toward D-asparagine. Belongs to the clavaminate synthase family. | 0.528 |
SCO3235 | SCO3236 | gene:17760853 | gene:17760854 | SCE29.04c, probable ABC transporter, len: 615aa; similar to many eg. TR:D1035364 (EMBL:AB019513) ABC transporter from Streptomyces coelicolor fasta scores; opt: 783, z-score: 794.3, E(): 0, (42.8% identity in 596 aa overlap). C-terminal half contains Pfam match to entry PF00005 ABC_tran, ABC transporter (score 184.50, E-value 1.7e-51) which itself contains Prosite matches to PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop). N-terminal half contains Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region., score 129.80, E [...] | Putative oxygenase; Catalyzes the 3-hydroxylation of L-asparagine to (2S,3S)-3- hydroxyasparagine. The 3-hydroxylated asparagine produced is incorporated at position 9 during the biosynthesis of the non- ribosomally synthesized calcium-dependent antibiotic (CDA), a 11- residue acidic lipopeptide lactone. Is able to hydroxylate only free L- asparagine, since it hydroxylates neither a CDA analog with unmodified Asn at position 9 nor a peptidyl-carrier-protein (PCP)-bound asparagine. Is not active toward D-asparagine. Belongs to the clavaminate synthase family. | 0.648 |
SCO3235 | SCO3237 | gene:17760853 | gene:17760855 | SCE29.04c, probable ABC transporter, len: 615aa; similar to many eg. TR:D1035364 (EMBL:AB019513) ABC transporter from Streptomyces coelicolor fasta scores; opt: 783, z-score: 794.3, E(): 0, (42.8% identity in 596 aa overlap). C-terminal half contains Pfam match to entry PF00005 ABC_tran, ABC transporter (score 184.50, E-value 1.7e-51) which itself contains Prosite matches to PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop). N-terminal half contains Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region., score 129.80, E [...] | Conserved hypothetical protein; SCE29.06c, unknown, len: 462 aa; similar to TR:O69954 (EMBL:AL023862) hypothetical protein from Streptomyces coelicolor (465 aa) fasta scores; opt: 2210, z-score: 2646.8, E(): 0, (70.8% identity in 452 aa overlap). | 0.545 |
SCO3235 | SCO3238 | gene:17760853 | gene:17760856 | SCE29.04c, probable ABC transporter, len: 615aa; similar to many eg. TR:D1035364 (EMBL:AB019513) ABC transporter from Streptomyces coelicolor fasta scores; opt: 783, z-score: 794.3, E(): 0, (42.8% identity in 596 aa overlap). C-terminal half contains Pfam match to entry PF00005 ABC_tran, ABC transporter (score 184.50, E-value 1.7e-51) which itself contains Prosite matches to PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop). N-terminal half contains Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region., score 129.80, E [...] | Hypothetical protein; SCE29.07c, unknown, len: 386 aa; similar to TR:O69953 (EMBL:AL023862) hypothetical protein from Streptomyces coelicolor (391 aa) fasta scores; opt: 1396, z-score: 1559.7, E(): 0, (58.6% identity in 389 aa overlap). Contains PS00730 AP endonucleases family 2 signature 2. | 0.503 |
SCO3235 | SCO3239 | gene:17760853 | gene:17760857 | SCE29.04c, probable ABC transporter, len: 615aa; similar to many eg. TR:D1035364 (EMBL:AB019513) ABC transporter from Streptomyces coelicolor fasta scores; opt: 783, z-score: 794.3, E(): 0, (42.8% identity in 596 aa overlap). C-terminal half contains Pfam match to entry PF00005 ABC_tran, ABC transporter (score 184.50, E-value 1.7e-51) which itself contains Prosite matches to PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop). N-terminal half contains Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region., score 129.80, E [...] | Conserved hypothetical protein; SCE29.08c, unknown, len: 289 aa; similar to TR:O69952 (EMBL:AL023862) hypothetical protein from Streptomyces coelicolor (282 aa) fasta scores; opt: 1391, z-score: 1679.9, E(): 0, (72.3% identity in 285 aa overlap). | 0.503 |
SCO3235 | SCO3240 | gene:17760853 | gene:17760858 | SCE29.04c, probable ABC transporter, len: 615aa; similar to many eg. TR:D1035364 (EMBL:AB019513) ABC transporter from Streptomyces coelicolor fasta scores; opt: 783, z-score: 794.3, E(): 0, (42.8% identity in 596 aa overlap). C-terminal half contains Pfam match to entry PF00005 ABC_tran, ABC transporter (score 184.50, E-value 1.7e-51) which itself contains Prosite matches to PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop). N-terminal half contains Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region., score 129.80, E [...] | Conserved hypothetical protein; SCE29.09c, unknown, len: 236 aa; similar to TR:O69951 (EMBL:AL023862) hypothetical protein from Streptomyces coelicolor (245 aa) fasta scores; opt: 416, z-score: 464.9, E(): 1.4e-18, (45.5% identity in 220 aa overlap). | 0.503 |
SCO3235 | SCO3241 | gene:17760853 | gene:17760859 | SCE29.04c, probable ABC transporter, len: 615aa; similar to many eg. TR:D1035364 (EMBL:AB019513) ABC transporter from Streptomyces coelicolor fasta scores; opt: 783, z-score: 794.3, E(): 0, (42.8% identity in 596 aa overlap). C-terminal half contains Pfam match to entry PF00005 ABC_tran, ABC transporter (score 184.50, E-value 1.7e-51) which itself contains Prosite matches to PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop). N-terminal half contains Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region., score 129.80, E [...] | SCE29.10c, possible isomerase, len: 290 aa; similar to TR:O69950 (EMBL:AL023862) hypothetical protein from Streptomyces coelicolor (315 aa) fasta scores; opt: 1116, z-score: 1331.4, E(): 0, (62.5% identity in 283 aa overlap). Also similar to SW:XYLA_STRDI xylose isomerase from Streptomyces diastaticus (388 aa) fasta scores; opt: 122, z-score: 148.8, E(): 0.56,25.0% identity in 296 aa overlap. | 0.503 |
SCO3235 | SCO3242 | gene:17760853 | gene:17760860 | SCE29.04c, probable ABC transporter, len: 615aa; similar to many eg. TR:D1035364 (EMBL:AB019513) ABC transporter from Streptomyces coelicolor fasta scores; opt: 783, z-score: 794.3, E(): 0, (42.8% identity in 596 aa overlap). C-terminal half contains Pfam match to entry PF00005 ABC_tran, ABC transporter (score 184.50, E-value 1.7e-51) which itself contains Prosite matches to PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop). N-terminal half contains Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region., score 129.80, E [...] | SCE29.11c, possible transferase, len: 291 aa; similar to TR:O69949 (EMBL:AL023862) hypothetical protein from Streptomyces coelicolor (363 aa) fasta scores; opt: 666, z-score: 682.9, E(): 9.9e-31, (51.3% identity in 312 aa overlap). Also similar to SW:UBIA_ECOLI 4-hydroxybenzoate octaprenyl transferase from Escherichia coli (290 aa) fasta scores; opt: 137, z-score: 150.2, E(): 0.47, (31.8% identity in 110 aa overlap). | 0.536 |
SCO3235 | SCO3243 | gene:17760853 | gene:17760861 | SCE29.04c, probable ABC transporter, len: 615aa; similar to many eg. TR:D1035364 (EMBL:AB019513) ABC transporter from Streptomyces coelicolor fasta scores; opt: 783, z-score: 794.3, E(): 0, (42.8% identity in 596 aa overlap). C-terminal half contains Pfam match to entry PF00005 ABC_tran, ABC transporter (score 184.50, E-value 1.7e-51) which itself contains Prosite matches to PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop). N-terminal half contains Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region., score 129.80, E [...] | SCE29.12c, possible myo-inositol phosphate synthase, len: 388 aa; similar to many e.g. TR:O69948 (EMBL:AL023862) from Streptomyces coelicolor (417 aa) fasta scores; opt: 955, z-score: 1034.1, E(): 0, (60.3% identity in 380 aa overlap) and SW:INO1_CITPA myo-inositol phosphate synthase from Citrus paradisi (grapefruit) fasta scores; opt: 323, z-score: 352.1, E(): 2.6e-12, (26.9% identity in 364 aa overlap). | 0.503 |
SCO3236 | SCO2993 | gene:17760854 | gene:17760605 | Putative oxygenase; Catalyzes the 3-hydroxylation of L-asparagine to (2S,3S)-3- hydroxyasparagine. The 3-hydroxylated asparagine produced is incorporated at position 9 during the biosynthesis of the non- ribosomally synthesized calcium-dependent antibiotic (CDA), a 11- residue acidic lipopeptide lactone. Is able to hydroxylate only free L- asparagine, since it hydroxylates neither a CDA analog with unmodified Asn at position 9 nor a peptidyl-carrier-protein (PCP)-bound asparagine. Is not active toward D-asparagine. Belongs to the clavaminate synthase family. | Hypothetical protein SCE50.21; SCE50.21, unknown, len: 184 aa. | 0.528 |
SCO3236 | SCO3235 | gene:17760854 | gene:17760853 | Putative oxygenase; Catalyzes the 3-hydroxylation of L-asparagine to (2S,3S)-3- hydroxyasparagine. The 3-hydroxylated asparagine produced is incorporated at position 9 during the biosynthesis of the non- ribosomally synthesized calcium-dependent antibiotic (CDA), a 11- residue acidic lipopeptide lactone. Is able to hydroxylate only free L- asparagine, since it hydroxylates neither a CDA analog with unmodified Asn at position 9 nor a peptidyl-carrier-protein (PCP)-bound asparagine. Is not active toward D-asparagine. Belongs to the clavaminate synthase family. | SCE29.04c, probable ABC transporter, len: 615aa; similar to many eg. TR:D1035364 (EMBL:AB019513) ABC transporter from Streptomyces coelicolor fasta scores; opt: 783, z-score: 794.3, E(): 0, (42.8% identity in 596 aa overlap). C-terminal half contains Pfam match to entry PF00005 ABC_tran, ABC transporter (score 184.50, E-value 1.7e-51) which itself contains Prosite matches to PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop). N-terminal half contains Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region., score 129.80, E [...] | 0.648 |
SCO3236 | SCO3237 | gene:17760854 | gene:17760855 | Putative oxygenase; Catalyzes the 3-hydroxylation of L-asparagine to (2S,3S)-3- hydroxyasparagine. The 3-hydroxylated asparagine produced is incorporated at position 9 during the biosynthesis of the non- ribosomally synthesized calcium-dependent antibiotic (CDA), a 11- residue acidic lipopeptide lactone. Is able to hydroxylate only free L- asparagine, since it hydroxylates neither a CDA analog with unmodified Asn at position 9 nor a peptidyl-carrier-protein (PCP)-bound asparagine. Is not active toward D-asparagine. Belongs to the clavaminate synthase family. | Conserved hypothetical protein; SCE29.06c, unknown, len: 462 aa; similar to TR:O69954 (EMBL:AL023862) hypothetical protein from Streptomyces coelicolor (465 aa) fasta scores; opt: 2210, z-score: 2646.8, E(): 0, (70.8% identity in 452 aa overlap). | 0.601 |
SCO3236 | SCO3238 | gene:17760854 | gene:17760856 | Putative oxygenase; Catalyzes the 3-hydroxylation of L-asparagine to (2S,3S)-3- hydroxyasparagine. The 3-hydroxylated asparagine produced is incorporated at position 9 during the biosynthesis of the non- ribosomally synthesized calcium-dependent antibiotic (CDA), a 11- residue acidic lipopeptide lactone. Is able to hydroxylate only free L- asparagine, since it hydroxylates neither a CDA analog with unmodified Asn at position 9 nor a peptidyl-carrier-protein (PCP)-bound asparagine. Is not active toward D-asparagine. Belongs to the clavaminate synthase family. | Hypothetical protein; SCE29.07c, unknown, len: 386 aa; similar to TR:O69953 (EMBL:AL023862) hypothetical protein from Streptomyces coelicolor (391 aa) fasta scores; opt: 1396, z-score: 1559.7, E(): 0, (58.6% identity in 389 aa overlap). Contains PS00730 AP endonucleases family 2 signature 2. | 0.593 |
SCO3236 | SCO3239 | gene:17760854 | gene:17760857 | Putative oxygenase; Catalyzes the 3-hydroxylation of L-asparagine to (2S,3S)-3- hydroxyasparagine. The 3-hydroxylated asparagine produced is incorporated at position 9 during the biosynthesis of the non- ribosomally synthesized calcium-dependent antibiotic (CDA), a 11- residue acidic lipopeptide lactone. Is able to hydroxylate only free L- asparagine, since it hydroxylates neither a CDA analog with unmodified Asn at position 9 nor a peptidyl-carrier-protein (PCP)-bound asparagine. Is not active toward D-asparagine. Belongs to the clavaminate synthase family. | Conserved hypothetical protein; SCE29.08c, unknown, len: 289 aa; similar to TR:O69952 (EMBL:AL023862) hypothetical protein from Streptomyces coelicolor (282 aa) fasta scores; opt: 1391, z-score: 1679.9, E(): 0, (72.3% identity in 285 aa overlap). | 0.593 |
SCO3236 | SCO3240 | gene:17760854 | gene:17760858 | Putative oxygenase; Catalyzes the 3-hydroxylation of L-asparagine to (2S,3S)-3- hydroxyasparagine. The 3-hydroxylated asparagine produced is incorporated at position 9 during the biosynthesis of the non- ribosomally synthesized calcium-dependent antibiotic (CDA), a 11- residue acidic lipopeptide lactone. Is able to hydroxylate only free L- asparagine, since it hydroxylates neither a CDA analog with unmodified Asn at position 9 nor a peptidyl-carrier-protein (PCP)-bound asparagine. Is not active toward D-asparagine. Belongs to the clavaminate synthase family. | Conserved hypothetical protein; SCE29.09c, unknown, len: 236 aa; similar to TR:O69951 (EMBL:AL023862) hypothetical protein from Streptomyces coelicolor (245 aa) fasta scores; opt: 416, z-score: 464.9, E(): 1.4e-18, (45.5% identity in 220 aa overlap). | 0.593 |
SCO3236 | SCO3241 | gene:17760854 | gene:17760859 | Putative oxygenase; Catalyzes the 3-hydroxylation of L-asparagine to (2S,3S)-3- hydroxyasparagine. The 3-hydroxylated asparagine produced is incorporated at position 9 during the biosynthesis of the non- ribosomally synthesized calcium-dependent antibiotic (CDA), a 11- residue acidic lipopeptide lactone. Is able to hydroxylate only free L- asparagine, since it hydroxylates neither a CDA analog with unmodified Asn at position 9 nor a peptidyl-carrier-protein (PCP)-bound asparagine. Is not active toward D-asparagine. Belongs to the clavaminate synthase family. | SCE29.10c, possible isomerase, len: 290 aa; similar to TR:O69950 (EMBL:AL023862) hypothetical protein from Streptomyces coelicolor (315 aa) fasta scores; opt: 1116, z-score: 1331.4, E(): 0, (62.5% identity in 283 aa overlap). Also similar to SW:XYLA_STRDI xylose isomerase from Streptomyces diastaticus (388 aa) fasta scores; opt: 122, z-score: 148.8, E(): 0.56,25.0% identity in 296 aa overlap. | 0.593 |
SCO3236 | SCO3242 | gene:17760854 | gene:17760860 | Putative oxygenase; Catalyzes the 3-hydroxylation of L-asparagine to (2S,3S)-3- hydroxyasparagine. The 3-hydroxylated asparagine produced is incorporated at position 9 during the biosynthesis of the non- ribosomally synthesized calcium-dependent antibiotic (CDA), a 11- residue acidic lipopeptide lactone. Is able to hydroxylate only free L- asparagine, since it hydroxylates neither a CDA analog with unmodified Asn at position 9 nor a peptidyl-carrier-protein (PCP)-bound asparagine. Is not active toward D-asparagine. Belongs to the clavaminate synthase family. | SCE29.11c, possible transferase, len: 291 aa; similar to TR:O69949 (EMBL:AL023862) hypothetical protein from Streptomyces coelicolor (363 aa) fasta scores; opt: 666, z-score: 682.9, E(): 9.9e-31, (51.3% identity in 312 aa overlap). Also similar to SW:UBIA_ECOLI 4-hydroxybenzoate octaprenyl transferase from Escherichia coli (290 aa) fasta scores; opt: 137, z-score: 150.2, E(): 0.47, (31.8% identity in 110 aa overlap). | 0.593 |
SCO3236 | SCO3243 | gene:17760854 | gene:17760861 | Putative oxygenase; Catalyzes the 3-hydroxylation of L-asparagine to (2S,3S)-3- hydroxyasparagine. The 3-hydroxylated asparagine produced is incorporated at position 9 during the biosynthesis of the non- ribosomally synthesized calcium-dependent antibiotic (CDA), a 11- residue acidic lipopeptide lactone. Is able to hydroxylate only free L- asparagine, since it hydroxylates neither a CDA analog with unmodified Asn at position 9 nor a peptidyl-carrier-protein (PCP)-bound asparagine. Is not active toward D-asparagine. Belongs to the clavaminate synthase family. | SCE29.12c, possible myo-inositol phosphate synthase, len: 388 aa; similar to many e.g. TR:O69948 (EMBL:AL023862) from Streptomyces coelicolor (417 aa) fasta scores; opt: 955, z-score: 1034.1, E(): 0, (60.3% identity in 380 aa overlap) and SW:INO1_CITPA myo-inositol phosphate synthase from Citrus paradisi (grapefruit) fasta scores; opt: 323, z-score: 352.1, E(): 2.6e-12, (26.9% identity in 364 aa overlap). | 0.593 |
SCO3236 | SCO3646 | gene:17760854 | gene:17761269 | Putative oxygenase; Catalyzes the 3-hydroxylation of L-asparagine to (2S,3S)-3- hydroxyasparagine. The 3-hydroxylated asparagine produced is incorporated at position 9 during the biosynthesis of the non- ribosomally synthesized calcium-dependent antibiotic (CDA), a 11- residue acidic lipopeptide lactone. Is able to hydroxylate only free L- asparagine, since it hydroxylates neither a CDA analog with unmodified Asn at position 9 nor a peptidyl-carrier-protein (PCP)-bound asparagine. Is not active toward D-asparagine. Belongs to the clavaminate synthase family. | Putative oxidoreductase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.575 |
SCO3237 | SCO3235 | gene:17760855 | gene:17760853 | Conserved hypothetical protein; SCE29.06c, unknown, len: 462 aa; similar to TR:O69954 (EMBL:AL023862) hypothetical protein from Streptomyces coelicolor (465 aa) fasta scores; opt: 2210, z-score: 2646.8, E(): 0, (70.8% identity in 452 aa overlap). | SCE29.04c, probable ABC transporter, len: 615aa; similar to many eg. TR:D1035364 (EMBL:AB019513) ABC transporter from Streptomyces coelicolor fasta scores; opt: 783, z-score: 794.3, E(): 0, (42.8% identity in 596 aa overlap). C-terminal half contains Pfam match to entry PF00005 ABC_tran, ABC transporter (score 184.50, E-value 1.7e-51) which itself contains Prosite matches to PS00211 ABC transporters family signature and PS00017 ATP/GTP-binding site motif A (P-loop). N-terminal half contains Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region., score 129.80, E [...] | 0.545 |