STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO3263Conserved hypothetical protein; SCE39.13c, unknown, len: 99 aa; similar to TR:CAC44711 (EMBL:AL596251) Streptomyces coelicolor conserved hypothetical protein SCBAC25E3.24, 101 aa; fasta scores: opt: 441 Z-score: 540.6 E(): 1.8e-22; 67.742% identity in 93 aa overlap. Contains possible coiled-coil region. (99 aa)    
Predicted Functional Partners:
SCO3265
Conserved hypothetical protein; SCE39.15c, unknown, len: 74aa; similar to TR:CAC44709 (EMBL:AL596251) conserved hypothetical protein SCBAC25E3.22 from Streptomyces coelicolor (74 aa) fasta scores; opt: 356, Z-score: 489.1, E(): 1.3e-19, 77.465% identity (77.465% ungapped) in 71 aa overlap.
       0.796
SCO3266
Hypothetical protein; SCE39.16c, unknown, len: 67aa.
       0.796
SCO3264
SCE39.14c, possible gntR-family regulator, len: 243aa; weak similarity to many egs. SW:FARR_ECOLI fatty acyl responsive regulator from Escherichia coli (240 aa) fasta scores; opt: 196, z-score: 243.9, E(): 2.8e-06, (24.3% identity in 243 aa overlap) and SW:KORA_STRLI KorA protein found to control plasmid transfer in the Streptomyces lividans plasmid pIJ101 (241 aa) fasta scores; opt: 158, z-score: 198.3, E(): 0.00098, (22.0% identity in 227 aa overlap). Contains Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family and Prosite match to PS00043 Bacterial regulator [...]
       0.794
SCO3268
SCE39.18c, putative secreted protein, len: 92 aa; similar to TR:CAC44706 (EMBL:AL596251) Streptomyces coelicolor conserved hypothetical protein SCBAC25E3.19, 92 aa; fasta scores: opt: 471 Z-score: 603.7 E(): 5.4e-26l; 81.522% identity in 92 aa overlap. Contains possible N-terminal region signal peptide sequence.
     
 0.682
SCO3982
SCBAC25E3.19, conserved hypothetical protein, len: 92 aa: strongly similar to TR:Q9X8E1 (EMBL:AL049573) hypothetical protein SCE39.18c from Streptomyces coelicolor (92 aa) fasta scores; opt: 471, Z-score: 618.1, 81.522% identity in 92 aa overlap. Contains TTA leucine codon, possible target for bldA regulation.
     
 0.682
SCO3988
Hypothetical protein; SCBAC25E3.25, unknown, len: 115 aa: no significant database matches.
      
 0.642
SCO3267
Hypothetical protein; SCE39.17, unknown, len: 66aa.
       0.563
SCO3986
SCBAC25E3.23, possible GntR-family transcriptional regulator, len: 243 aa: similar to TR:Q9X8D7 (EMBL:AL049573) putative GntR-family regulator from Streptomyces coelicolor (243 aa) fasta scores; opt: 1025, Z-score: 1169.6, 67.083% identity (67.083% ungapped) in 240 aa overlap. Contains Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family and Prosite match to PS00043 Bacterial regulatory proteins, gntR family signature.
     
 0.554
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.